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TRPC6

Transient receptor potential cation channel, subfamily C, member 6 or Transient receptor potential canonical 6, also known as TRPC6, is a protein encoded in the human by the TRPC6 gene. TRPC6 is a transient receptor potential channel of the classical TRPC subfamily.

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Aliases
TRPC6, FSGS2, TRP6, transient receptor potential cation channel subfamily C member 6
Band
11q22.1 · 9 A1|9 2.46 cM
Bgee
right lung · upper lobe of left lung · right uterine tube · testicle · left lobe of thyroid gland
BioGPS
n/a
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

Interactions

Ligands

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Map overview Semantic statistics

TRPC6

Nodes80
Edges79
Triples127
Avg. degree1.98
Density0.025
Components1

How this topic connects Entity context

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TRPC6

Top relations

Gene ontology · 37
TRPC6 → actin binding, actinin binding, ageing, ATPase binding, calcium channel activity, calcium ion transmembrane transport, calcium ion transport, cation channel activity, cation channel complex, cation transport, cellular response to hydrogen peroxide, cellular response to hypoxia, clathrin binding, cytoplasm, inositol 1,4,5 trisphosphate binding, integral component of membrane, integral component of plasma membrane, ion channel activity, ion transport, manganese ion transport
Bgee · 20
TRPC6 → Achilles tendon, body of femur, cumulus cell, dentate gyrus of hippocampal formation granule cell, embryo, hippocampus proper, left lobe of thyroid gland, left lung lobe, lens, lumbar spinal ganglion, right lobe of liver, right lobe of thyroid gland, right lung, right uterine tube, stromal cell of endometrium, subcutaneous adipose tissue, substantia nigra, testicle, upper lobe of left lung, visceral pleura
RNA expression pattern · 20
TRPC6 → Achilles tendon, body of femur, cumulus cell, dentate gyrus of hippocampal formation granule cell, embryo, hippocampus proper, left lobe of thyroid gland, left lung lobe, lens, lumbar spinal ganglion, right lobe of liver, right lobe of thyroid gland, right lung, right uterine tube, stromal cell of endometrium, subcutaneous adipose tissue, substantia nigra, testicle, upper lobe of left lung, visceral pleura
related to Ligands · 7
TRPC6 → Hyperforin, Hypericum, John's Wort, Recent, St, These, Two
related to In blood vessels · 6
TRPC6 → Conversely, However, Small, This, TPRC6-mediated, When
related to In the central nervous system · 4
TRPC6 → NMDA, NMDAR, PSD-95, Research
related to In the kidneys · 4
TRPC6 → Despite, Nevertheless, Podocytes, Within
related to External links · 3
TRPC6 → Medicine Medical Subject Headings, MeSH, National Library
related to Interactions · 3
TRPC6 → APP, FYN, TRPC2
Band · 2
TRPC6 → 11q22.1, 9 A1|9 2.46 cM

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Important terminology

channels calcium human channel bp blood chr band cation gene activity receptor function pressure chromosome 11 ions trpc3 protein transient

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TRPC6AliasesTRPC6, FSGS2, TRP6, transient receptor potential cation channel subfamily C member 61.00infobox
TRPC6Band11q22.11.00infobox
TRPC6Band9 A1|9 2.46 cM1.00infobox
TRPC6Bgeeright lung1.00infobox
TRPC6Bgeeupper lobe of left lung1.00infobox
TRPC6Bgeeright uterine tube1.00infobox
TRPC6Bgeetesticle1.00infobox
TRPC6Bgeeleft lobe of thyroid gland1.00infobox
TRPC6Bgeeright lobe of thyroid gland1.00infobox
TRPC6BgeeAchilles tendon1.00infobox
TRPC6Bgeestromal cell of endometrium1.00infobox
TRPC6Bgeevisceral pleura1.00infobox
TRPC6Bgeesubcutaneous adipose tissue1.00infobox
TRPC6Bgeelumbar spinal ganglion1.00infobox
TRPC6Bgeeright lobe of liver1.00infobox
TRPC6Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
TRPC6Bgeelens1.00infobox
TRPC6Bgeecumulus cell1.00infobox
TRPC6Bgeesubstantia nigra1.00infobox
TRPC6Bgeeembryo1.00infobox
TRPC6Bgeehippocampus proper1.00infobox
TRPC6Bgeeleft lung lobe1.00infobox
TRPC6Bgeebody of femur1.00infobox
TRPC6BioGPSn/a1.00infobox
TRPC6Chr.Chromosome 11 (human)1.00infobox
TRPC6Chr.Chromosome 9 (mouse)1.00infobox
TRPC6DatabasesNCBI: entry; OMA: entry1.00infobox
TRPC6End101,872,562 bp1.00infobox
TRPC6End8,680,742 bp1.00infobox
TRPC6EnsemblENSG000001376721.00infobox

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