TBX3

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Structure and function

DNA-binding domain Palindromic Phosphorylation Kinases Mitogen-activated protein

13 related topics

Transcript splicing

Alternative processing Isoforms Intron

3 related topics

Role in development

BCL9

1 related topics

Role in stem cells

Embryonic stem cells

1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TBX3, TBX3-ISO, UMS, XHL, T-box 3, T-box transcription factor 3
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H6F
Band: 12q24.21 · 5 F|5 60.34 cM
Bgee: right adrenal cortex · left adrenal cortex · urethra · stromal cell of endometrium · seminal vesicula
BioGPS: More reference expression data
Chr.: Chromosome 12 (human) · Chromosome 5 (mouse)

Topics to explore

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Overview

Protein
Gene
Transcription factors Transcription factor
T-box
Tbx2
Tbx5 TBX5 (gene)
Chromosome
Exons Exon

Transcript splicing

Alternative processing Alternative splicing
Isoforms Protein isoform
Intron

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes32

Edges31

Triples189

Avg. degree1.94

Density0.0625

Components1

How this topic connects Entity context

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TBX3

Top relations

Gene ontology · 54

TBX3 → animal organ morphogenesis, anterior/posterior axis specification, embryo, atrioventricular bundle cell differentiation, blood vessel development, branching involved in mammary gland duct morphogenesis, cardiac muscle cell differentiation, cardiac muscle cell fate commitment, cellular senescence, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic heart tube development, embryonic hindlimb morphogenesis, female genitalia development, follicle-stimulating hormone secretion, forelimb morphogenesis, heart looping

related to Structure and function · 29

TBX3 → A-CDK2, ACACCT AGGTGTGAAATT, AKT3, DBD, DNA, DNA-binding, E-cadherin, Eomes, Furthermore, G/C, Gata6, Indeed, MAP, PTEN, R1, R2, S720, Sox17, SP190, SP354

Bgee · 19

TBX3 → adrenal gland, coelomic epithelium, genital tubercle, left adrenal cortex, left lobe of thyroid gland, lobe of prostate, lumbar spinal ganglion, medullary collecting duct, pelvic ganglion, placenta, prostate, right adrenal cortex, right lobe of thyroid gland, right lung, seminal vesicula, stromal cell of endometrium, transitional epithelium of ureter, transitional epithelium of urinary bladder, urethra

RNA expression pattern · 19

related to Role in stem cells · 13

TBX3 → Adult, C-MYC, Embryonic, ESC-like, ESCs, Firstly, In, Induced, KLF4, LIN-28A, Nanog, OCT4, SOX2

related to External links · 9

TBX3 → Medicine Medical Subject Headings, MeSH, National Library, O15119, Overview, PDB, PDBe-KB, T-box, UniProt

related to Clinical significance · 8

TBX3 → DNA, In, Missense, RD1, Several UMS, T-domain, These, UMS

related to Role in development · 5

TBX3 → BCL9, During, E16, These, Wnt

is a · 3

TBX3 → important factor that, member of the Tbx2 subfamily which includes Tbx2, protein that in humans is encoded by the TBX3 gene.T-box 3

related to Transcript splicing · 3

TBX3 → Alternative, T-box DNA, The

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein t-box human transcription mouse function cells cell bp binding chromosome stem cancer factor 12 embryonic chr band development

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
TBX3	Aliases	TBX3, TBX3-ISO, UMS, XHL, T-box 3, T-box transcription factor 3	1.00	infobox
TBX3	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H6F	1.00	infobox
TBX3	Band	12q24.21	1.00	infobox
TBX3	Band	5 F\|5 60.34 cM	1.00	infobox
TBX3	Bgee	right adrenal cortex	1.00	infobox
TBX3	Bgee	left adrenal cortex	1.00	infobox
TBX3	Bgee	urethra	1.00	infobox
TBX3	Bgee	stromal cell of endometrium	1.00	infobox
TBX3	Bgee	seminal vesicula	1.00	infobox
TBX3	Bgee	prostate	1.00	infobox
TBX3	Bgee	right lobe of thyroid gland	1.00	infobox
TBX3	Bgee	right lung	1.00	infobox
TBX3	Bgee	left lobe of thyroid gland	1.00	infobox
TBX3	Bgee	placenta	1.00	infobox
TBX3	Bgee	genital tubercle	1.00	infobox
TBX3	Bgee	medullary collecting duct	1.00	infobox
TBX3	Bgee	transitional epithelium of ureter	1.00	infobox
TBX3	Bgee	lobe of prostate	1.00	infobox
TBX3	Bgee	adrenal gland	1.00	infobox
TBX3	Bgee	transitional epithelium of urinary bladder	1.00	infobox
TBX3	Bgee	pelvic ganglion	1.00	infobox
TBX3	Bgee	lumbar spinal ganglion	1.00	infobox
TBX3	Bgee	coelomic epithelium	1.00	infobox
TBX3	BioGPS	More reference expression data	1.00	infobox
TBX3	Chr.	Chromosome 12 (human)	1.00	infobox
TBX3	Chr.	Chromosome 5 (mouse)	1.00	infobox
TBX3	Databases	NCBI: entry; OMA: entry	1.00	infobox
TBX3	End	114,684,175 bp	1.00	infobox
TBX3	End	119,822,789 bp	1.00	infobox
TBX3	Ensembl	ENSG00000135111	1.00	infobox

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Connections between topic areas Semantic bridges

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Min side: 3