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BCL9: Clinical significance, Function & Related gene problems

B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene.

Language: English [EN]
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BCL9 topic overview

The analysis highlights Clinical significance, Function and Related gene problems as prominent areas in the source structure around BCL9.

Related topics
22
Source areas
4
Connected nodes
26
Extracted relationships
95
Concept neighborhoods
13
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 14 topics
Function · 4 topics
Overview · 2 topics
Related gene problems · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GL7, 2VP7, 2VPB, 2VPD, 2VPE, 2VPG, 3SL9
Band
1q21.2 · 3|3 F2.1
Bgee
ganglionic eminence · ventricular zone · islet of Langerhans · right uterine tube · smooth muscle tissue
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Related gene problems

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BCL9 connects Entity context

The extracted context around BCL9 shows recurring relationship patterns in the source. For example, BCL9 → body of uterus, cardia, cerebellar cortex, cerebellar hemisphere, ganglionic eminence, genital tubercle, islet of Langerhans, left uterine tube, neural layer of retina, neural tube, Paneth cell, right uterine tube, Rostral migratory stream, secondary oocyte, smooth muscle tissue, tail of embryo, ventricular zone, zygote Another extracted example is BCL9 → beta-catenin binding, beta-catenin-TCF complex, beta-catenin-TCF complex assembly, canonical Wnt signaling pathway, cis-Golgi network, cytoplasm, Golgi apparatus, myotube differentiation involved in skeletal muscle regeneration, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, protein binding, regulation of transforming growth factor beta receptor signaling pathway, skeletal muscle cell differentiation, somatic stem cell population maintenance, transcription coactivator activity, Wnt signaling pathway. Use these groups to spot repeated connection types before inspecting the individual relationships.

BCL9

Top relations

Bgee · 18
BCL9 → body of uterus, cardia, cerebellar cortex, cerebellar hemisphere, ganglionic eminence, genital tubercle, islet of Langerhans, left uterine tube, neural layer of retina, neural tube, Paneth cell, right uterine tube, Rostral migratory stream, secondary oocyte, smooth muscle tissue, tail of embryo, ventricular zone, zygote
RNA expression pattern · 18
BCL9 → body of uterus, cardia, cerebellar cortex, cerebellar hemisphere, ganglionic eminence, genital tubercle, islet of Langerhans, left uterine tube, neural layer of retina, neural tube, Paneth cell, right uterine tube, Rostral migratory stream, secondary oocyte, smooth muscle tissue, tail of embryo, ventricular zone, zygote
Gene ontology · 17
BCL9 → beta-catenin binding, beta-catenin-TCF complex, beta-catenin-TCF complex assembly, canonical Wnt signaling pathway, cis-Golgi network, cytoplasm, Golgi apparatus, myotube differentiation involved in skeletal muscle regeneration, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, protein binding, regulation of transforming growth factor beta receptor signaling pathway, skeletal muscle cell differentiation, somatic stem cell population maintenance, transcription coactivator activity, Wnt signaling pathway
related to External links · 8
BCL9 → B-cell CLL/lymphoma, Human BCL9, O00512, Overview, PDB, PDBe-KB, UCSC Genome Browser, UniProt
related to Function · 7
BCL9 → BCL9L, Danio, Mus, Recent, This, Wnt, Wnt/β-catenin
related to Clinical significance · 4
BCL9 → B-cell, BCL9L, It, The
Band · 2
BCL9 → 1q21.2, 3|3 F2.1
Chr. · 2
BCL9 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
BCL9 → 147,626,216 bp, 97,205,233 bp
Aliases · 1
BCL9 → BCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bcl9l human bp b-cell chr band protein wnt lymphoma chromosome location pygo2 mouse cll function enamel transcription clinical significance

BCL9 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around BCL9. Examples in this analysis include BCL9 → Aliases → BCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator and BCL9 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GL7, 2VP7, 2VPB, 2VPD, 2VPE, 2VPG, 3SL9. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BCL9AliasesBCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator1.00infobox
BCL9Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GL7, 2VP7, 2VPB, 2VPD, 2VPE, 2VPG, 3SL91.00infobox
BCL9Band1q21.21.00infobox
BCL9Band3|3 F2.11.00infobox
BCL9Bgeeganglionic eminence1.00infobox
BCL9Bgeeventricular zone1.00infobox
BCL9Bgeeislet of Langerhans1.00infobox
BCL9Bgeeright uterine tube1.00infobox
BCL9Bgeesmooth muscle tissue1.00infobox
BCL9Bgeeleft uterine tube1.00infobox
BCL9Bgeebody of uterus1.00infobox
BCL9Bgeecerebellar cortex1.00infobox
BCL9Bgeecerebellar hemisphere1.00infobox
BCL9Bgeecardia1.00infobox
BCL9Bgeegenital tubercle1.00infobox
BCL9Bgeetail of embryo1.00infobox
BCL9Bgeezygote1.00infobox
BCL9BgeeRostral migratory stream1.00infobox
BCL9Bgeeneural layer of retina1.00infobox
BCL9Bgeesecondary oocyte1.00infobox
BCL9Bgeeneural tube1.00infobox
BCL9BgeePaneth cell1.00infobox
BCL9BioGPSMore reference expression data1.00infobox
BCL9Chr.Chromosome 1 (human)1.00infobox
BCL9Chr.Chromosome 3 (mouse)1.00infobox
BCL9DatabasesNCBI: entry; OMA: entry1.00infobox
BCL9End147,626,216 bp1.00infobox
BCL9End97,205,233 bp1.00infobox
BCL9EnsemblENSG000001161281.00infobox
BCL9Entrez6071.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BCL9 bring nearby vocabulary together. In this analysis, examples include Bcl9l, Gene and Wnt. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BCL9
    • Bcl9l
    • Gene
    • Wnt
    • Human
    • Enamel
    • Pygo2
    • Protein
    • Associated
    • Function
    • Functions
    • Role
    • Signaling
  • bcl9
    • Bcl9l
    • Gene
    • Wnt
    • Human
    • Enamel
    • Pygo2
    • Protein
    • Associated
    • Function
    • Functions
    • Role
    • Signaling
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Cell
    • Coactivator
    • Humans
    • Search
    • Transcription
    • 1q21
    • Associated
  • bcl9l
    • Wnt
    • Pygo2
    • Functions
    • Role
    • Signaling
    • Tissue-specific
    • Transcriptional
    • Enamel
    • Protein
    • Gene
    • Human
    • Mouse
  • b-cell acute lymphoblastic leukemia
    • Cll
    • Lymphoma
    • Pdb
    • May
    • Significance
    • Protein
    • Bcl9
    • External
    • Gene
    • Cell
    • Coactivator
    • Encoded
  • function
    • Cell
    • Coactivator
    • Search
    • Transcription
    • Chromosome
    • Location
    • Bp
    • Chr
    • External
    • O00512
    • Pdb
    • Uniprot
  • related gene problems
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Cell
    • Coactivator
    • Humans
    • Search
    • Transcription
    • 1q21
    • Associated
  • lymphoma
    • Pdb
    • Clinical
    • Significance
    • Protein
    • External
    • Cell
    • Coactivator
    • Encoded
    • Gene
    • Humans
    • O00512
    • Search

Connections between topic areas Semantic bridges

For BCL9, one of the stronger structural bridges in this analysis connects BCL9 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BCL9Clinical significance · splits 12 ⟂ 15
BCL9Function · splits 22 ⟂ 5
BCL9Overview · splits 24 ⟂ 3
BCL9Related gene problems · splits 24 ⟂ 3

Map overview Semantic statistics

BCL9

Nodes27
Edges26
Triples95
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around BCL9 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Related gene problems, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BCL9 · EN edition · Analysis: TopicsToTalkAbout

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