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Beta-actin

Beta-actin, or Actin beta (HUGO Gene Nomenclature Committee abbreviation ACTB/ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the…

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3 related topics

Interactions

4 related topics

Clinical relevance

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Overview

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Aliases
ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE
Band
7p22.1 · 5 G2|5 81.8 cM
Bgee
saphenous vein · urethra · postcentral gyrus · synovial joint · orbitofrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

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Overview

Interactions

Clinical relevance

Applications

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Map overview Semantic statistics

Beta-actin

Nodes18
Edges17
Triples99
Avg. degree1.89
Density0.111111
Components1

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Beta-actin

Top relations

Gene ontology · 36
Beta-actin → ATP binding, blood microparticle, cell junction assembly, cortical cytoskeleton, cytoplasm, cytoplasmic ribonucleoprotein granule, cytoskeleton, cytoskeleton organization, cytosol, dense body, ephrin receptor signaling pathway, epigenetic maintenance of chromatin in transcription-competent conformation, extracellular exosome, extracellular space, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, identical protein binding, kinesin binding, membrane, membrane organization
Bgee · 20
Beta-actin → abdominal wall, Brodmann area 46, Gonadal ridge, human fetus, lateral septal nucleus, mandibular prominence, maxillary prominence, medial ganglionic eminence, migratory enteric neural crest cell, mucosa of ileum, nipple, olfactory bulb, orbitofrontal cortex, postcentral gyrus, saphenous vein, synovial joint, urethra, vas deferens, vena cava, ventromedial nucleus
RNA expression pattern · 20
Beta-actin → abdominal wall, Brodmann area 46, Gonadal ridge, human fetus, lateral septal nucleus, mandibular prominence, maxillary prominence, medial ganglionic eminence, migratory enteric neural crest cell, mucosa of ileum, nipple, olfactory bulb, orbitofrontal cortex, postcentral gyrus, saphenous vein, synovial joint, urethra, vas deferens, vena cava, ventromedial nucleus
Band · 2
Beta-actin → 5 G2|5 81.8 cM, 7p22.1
Chr. · 2
Beta-actin → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
Beta-actin → 142,892,509 bp, 5,563,902 bp
Aliases · 1
Beta-actin → ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta
Available structures · 1
Beta-actin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE
BioGPS · 1
Beta-actin → More reference expression data
Databases · 1
Beta-actin → NCBI: entry; OMA: entry

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Important terminology

actin gene bp human beta chr actb band chromosome actins location one mouse protein involved cell constituent cytoskeletal external pdb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Beta-actinAliasesACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta1.00infobox
Beta-actinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BYH, 3D2U, 3J82, 3LUE1.00infobox
Beta-actinBand7p22.11.00infobox
Beta-actinBand5 G2|5 81.8 cM1.00infobox
Beta-actinBgeesaphenous vein1.00infobox
Beta-actinBgeeurethra1.00infobox
Beta-actinBgeepostcentral gyrus1.00infobox
Beta-actinBgeesynovial joint1.00infobox
Beta-actinBgeeorbitofrontal cortex1.00infobox
Beta-actinBgeemucosa of ileum1.00infobox
Beta-actinBgeeBrodmann area 461.00infobox
Beta-actinBgeenipple1.00infobox
Beta-actinBgeevena cava1.00infobox
Beta-actinBgeeolfactory bulb1.00infobox
Beta-actinBgeehuman fetus1.00infobox
Beta-actinBgeevas deferens1.00infobox
Beta-actinBgeelateral septal nucleus1.00infobox
Beta-actinBgeeGonadal ridge1.00infobox
Beta-actinBgeemandibular prominence1.00infobox
Beta-actinBgeemigratory enteric neural crest cell1.00infobox
Beta-actinBgeemaxillary prominence1.00infobox
Beta-actinBgeeventromedial nucleus1.00infobox
Beta-actinBgeeabdominal wall1.00infobox
Beta-actinBgeemedial ganglionic eminence1.00infobox
Beta-actinBioGPSMore reference expression data1.00infobox
Beta-actinChr.Chromosome 7 (human)1.00infobox
Beta-actinChr.Chromosome 5 (mouse)1.00infobox
Beta-actinDatabasesNCBI: entry; OMA: entry1.00infobox
Beta-actinEnd5,563,902 bp1.00infobox
Beta-actinEnd142,892,509 bp1.00infobox

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