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Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth.
History, Community, Culture & Applications
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Sofosbuvir | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Sofosbuvir | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Sofosbuvir | ATC code | J05AP08 (WHO) J05AP51 (WHO) J05AP55 (WHO) J05AP56 (WHO) | 1.00 | infobox |
| Sofosbuvir | Bioavailability | 92% | 1.00 | infobox |
| Sofosbuvir | CAS Number | 1190307-88-0 | 1.00 | infobox |
| Sofosbuvir | ChEBI | CHEBI:85083 Y | 1.00 | infobox |
| Sofosbuvir | ChEMBL | ChEMBL1259059 | 1.00 | infobox |
| Sofosbuvir | ChemSpider | 26286922 | 1.00 | infobox |
| Sofosbuvir | CompTox Dashboard (EPA) | DTXSID701027632 | 1.00 | infobox |
| Sofosbuvir | Drug class | HCV polymerase inhibitor | 1.00 | infobox |
| Sofosbuvir | DrugBank | DB08934 | 1.00 | infobox |
| Sofosbuvir | ECHA InfoCard | 100.224.393 | 1.00 | infobox |
| Sofosbuvir | Elimination half-life | 0.4 hrs (sofosbuvir) 27 hrs (inactive metabolite GS-331007) | 1.00 | infobox |
| Sofosbuvir | Excretion | 80% urine, 14% feces (mostly as GS-331007) | 1.00 | infobox |
| Sofosbuvir | Formula | C22H29FN3O9P | 1.00 | infobox |
| Sofosbuvir | IUPHAR/BPS | 7368 | 1.00 | infobox |
| Sofosbuvir | KEGG | D10366 | 1.00 | infobox |
| Sofosbuvir | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Sofosbuvir | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Sofosbuvir | Legal status | US: ℞-only | 1.00 | infobox |
| Sofosbuvir | Legal status | EU: Rx-only | 1.00 | infobox |
| Sofosbuvir | License data | EU EMA: by INN | 1.00 | infobox |
| Sofosbuvir | License data | US DailyMed: Sofosbuvir | 1.00 | infobox |
| Sofosbuvir | License data | US FDA: Sofosbuvir | 1.00 | infobox |
| Sofosbuvir | MedlinePlus | a614014 | 1.00 | infobox |
| Sofosbuvir | Metabolism | Quickly activated to triphosphate (CatA/CES1, HIST1, phosphorylation) | 1.00 | infobox |
| Sofosbuvir | Molar mass | 529.458 g·mol−1 | 1.00 | infobox |
| Sofosbuvir | Other names | PSI-7977; GS-7977 | 1.00 | infobox |
| Sofosbuvir | Pregnancy category | AU: B1 | 1.00 | infobox |
| Sofosbuvir | Protein binding | 61–65% | 1.00 | infobox |
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