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The ProTide technology is a prodrug approach used in molecular biology and drug design. It is designed to deliver nucleotide analogues (as monophosphate) into the cell (ProTide: PROdrug + nucleoTIDE). This technology was invented by Professor Chris McGuigan from the School of Pharmacy and Pharmaceutical Sciences at Cardiff University in the early 1990s.…
Applications, Technology & Science
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cell azt d4t phosphoramidates nucleoside nucleotide activity sofosbuvir parent jm active cem technology prodrug alanine first effective tk- thus approach
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| sofosbuvir | instance of | ProTides form a critical part of antiviral drugs | 0.80 | text |
| tenofovir alafenamide | instance of | ProTides form a critical part of antiviral drugs | 0.80 | text |
| and remdesivir | instance of | ProTides form a critical part of antiviral drugs | 0.80 | text |
| Protide | has application | The ProTide | 0.60 | section |
| Protide | has application | CTSA | 0.60 | section |
| Protide | has application | CES1 | 0.60 | section |
| Protide | has application | Tenofovir | 0.60 | section |
| Protide | has application | ProTides | 0.60 | section |
| Protide | has application | For | 0.60 | section |
| Protide | has application | GS-334750 | 0.60 | section |
| Protide | has application | Hepatitis | 0.60 | section |
| Protide | has application | Sofosbuvir | 0.60 | section |
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