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SKAP1: Interactions & Overview

Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene.

Language: English [EN]
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SKAP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around SKAP1.

Related topics
15
Source areas
2
Connected nodes
17
Extracted relationships
100
Concept neighborhoods
13
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 11 topics
Interactions · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D
Band
17q21.32 · 11|11 D
Bgee
granulocyte · right lobe of liver · right uterine tube · lymph node · blood
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SKAP1 connects Entity context

The extracted context around SKAP1 shows recurring relationship patterns in the source. For example, SKAP1 → adaptive immune response, cell migration, cell-cell junction, cellular response to epidermal growth factor stimulus, cytoplasm, cytosol, immune system process, immunological synapse, membrane, microtubule cytoskeleton organization, microtubule plus-end, microtubule plus-end binding, nucleus, plasma membrane, plasma membrane raft, positive regulation of adaptive immune response, positive regulation of cell adhesion, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of cell-matrix adhesion, positive regulation of heterotypic cell-cell adhesion Another extracted example is SKAP1 → anterior pituitary, blood, embryo, granulocyte, islet of Langerhans, left testis, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, pituitary gland, primary oocyte, right adrenal cortex, right lobe of liver, right testis, right uterine tube, secondary oocyte, seminal vesicula, thymus, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

SKAP1

Top relations

Gene ontology · 36
SKAP1 → adaptive immune response, cell migration, cell-cell junction, cellular response to epidermal growth factor stimulus, cytoplasm, cytosol, immune system process, immunological synapse, membrane, microtubule cytoskeleton organization, microtubule plus-end, microtubule plus-end binding, nucleus, plasma membrane, plasma membrane raft, positive regulation of adaptive immune response, positive regulation of cell adhesion, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of cell-matrix adhesion, positive regulation of heterotypic cell-cell adhesion
Bgee · 19
SKAP1 → anterior pituitary, blood, embryo, granulocyte, islet of Langerhans, left testis, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, pituitary gland, primary oocyte, right adrenal cortex, right lobe of liver, right testis, right uterine tube, secondary oocyte, seminal vesicula, thymus, zygote
RNA expression pattern · 19
SKAP1 → anterior pituitary, blood, embryo, granulocyte, islet of Langerhans, left testis, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, pituitary gland, primary oocyte, right adrenal cortex, right lobe of liver, right testis, right uterine tube, secondary oocyte, seminal vesicula, thymus, zygote
related to Interactions · 3
SKAP1 → FYB, FYN, PTPRC
Band · 2
SKAP1 → 11|11 D, 17q21.32
Chr. · 2
SKAP1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
SKAP1 → 48,430,275 bp, 96,649,956 bp
Aliases · 1
SKAP1 → SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1
Available structures · 1
SKAP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D
BioGPS · 1
SKAP1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene bp chr human band chromosome 17 adapter encoded mouse adhesion activation location additional src phosphoprotein cell activity domain

SKAP1 relationships Subject–Predicate–Object triples

TTTA extracted 100 structured relationships around SKAP1. Examples in this analysis include SKAP1 → Aliases → SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1 and SKAP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SKAP1AliasesSKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 11.00infobox
SKAP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D1.00infobox
SKAP1Band17q21.321.00infobox
SKAP1Band11|11 D1.00infobox
SKAP1Bgeegranulocyte1.00infobox
SKAP1Bgeeright lobe of liver1.00infobox
SKAP1Bgeeright uterine tube1.00infobox
SKAP1Bgeelymph node1.00infobox
SKAP1Bgeeblood1.00infobox
SKAP1Bgeepituitary gland1.00infobox
SKAP1Bgeeright testis1.00infobox
SKAP1Bgeeleft testis1.00infobox
SKAP1Bgeeanterior pituitary1.00infobox
SKAP1Bgeeright adrenal cortex1.00infobox
SKAP1Bgeethymus1.00infobox
SKAP1Bgeezygote1.00infobox
SKAP1Bgeesecondary oocyte1.00infobox
SKAP1Bgeeprimary oocyte1.00infobox
SKAP1Bgeemesenteric lymph nodes1.00infobox
SKAP1Bgeeislet of Langerhans1.00infobox
SKAP1Bgeeseminal vesicula1.00infobox
SKAP1Bgeeembryo1.00infobox
SKAP1Bgeelumbar subsegment of spinal cord1.00infobox
SKAP1BioGPSMore reference expression data1.00infobox
SKAP1Chr.Chromosome 17 (human)1.00infobox
SKAP1Chr.Chromosome 11 (mouse)1.00infobox
SKAP1DatabasesNCBI: entry; OMA: entry1.00infobox
SKAP1End48,430,275 bp1.00infobox
SKAP1End96,649,956 bp1.00infobox
SKAP1EnsemblENSG000001412931.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SKAP1 bring nearby vocabulary together. In this analysis, examples include Gene, Binding and Factor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SKAP1
    • Gene
    • Binding
    • Factor
    • Kinase
    • Search
    • Src
    • Activation
    • Adhesion
    • Location
    • Mouse
    • Chromosome
    • Human
  • skap1
    • Gene
    • Binding
    • Factor
    • Kinase
    • Search
    • Src
    • Activation
    • Adhesion
    • Location
    • Mouse
    • Chromosome
    • Human
  • adapter protein
    • Encoded
    • Protein
    • Gene
    • Activity
    • Cell
    • Domain
    • Receptor
    • Sh3
    • Signaling
    • Activation
    • Adhesion
    • Integrins
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Protein
    • Skap1
    • Activity
    • Cell
    • End
    • Kinase
    • Phosphoprotein
  • t cell
    • Activity
    • Gene
    • Protein
    • Additional
    • Binding
    • Domain
    • End
    • Factor
    • Kinase
    • Receptor
    • Search
    • Sh3
  • ph domain
    • Sh3
    • Protein
    • Binding
    • End
    • Factor
    • Kinase
    • Receptor
    • Search
    • Signaling
    • Activation
    • Adhesion
    • Encoded
  • sh3 domain
    • Sh3
    • Protein
    • Binding
    • End
    • Factor
    • Kinase
    • Receptor
    • Search
    • Signaling
    • Activation
    • Adhesion
    • Encoded
  • exchange factor
    • Erk
    • Rasgrp1
    • Skap1
    • End
    • Kinase
    • Receptor
    • Search
    • Sh3
    • Signaling
    • Location
    • Mouse
    • Band

Connections between topic areas Semantic bridges

For SKAP1, one of the stronger structural bridges in this analysis connects SKAP1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SKAP1Overview · splits 6 ⟂ 12
SKAP1Interactions · splits 13 ⟂ 5

Map overview Semantic statistics

SKAP1

Nodes18
Edges17
Triples100
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around SKAP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SKAP1 · EN edition · Analysis: TopicsToTalkAbout

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