SKAP1

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Interactions

Interact FYN PTPRC FYB

4 related topics

Overview

Adapter protein Gene T cell PH domain SH3 domain

11 related topics

Key facts & relationships

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Aliases: SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D
Band: 17q21.32 · 11|11 D
Bgee: granulocyte · right lobe of liver · right uterine tube · lymph node · blood
BioGPS: More reference expression data
Chr.: Chromosome 17 (human) · Chromosome 11 (mouse)

Topics to explore

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Overview

Adapter protein Signal transducing adaptor protein
Gene
T cell
PH domain
SH3 domain
Inside-out signaling Inside-out signaling?action=edit&redlink=1
Integrins Integrin
LFA-1
Exchange factor Guanine nucleotide exchange factor
RasGRP1
ERK Extracellular signal-regulated kinases

Interactions

Interact Protein-protein interaction
FYN
PTPRC
FYB

Advanced semantic analysis

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Map overview Semantic statistics

Nodes18

Edges17

Triples100

Avg. degree1.89

Density0.111111

Components1

How this topic connects Entity context

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SKAP1

Top relations

Gene ontology · 36

SKAP1 → adaptive immune response, cell migration, cell-cell junction, cellular response to epidermal growth factor stimulus, cytoplasm, cytosol, immune system process, immunological synapse, membrane, microtubule cytoskeleton organization, microtubule plus-end, microtubule plus-end binding, nucleus, plasma membrane, plasma membrane raft, positive regulation of adaptive immune response, positive regulation of cell adhesion, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of cell-matrix adhesion, positive regulation of heterotypic cell-cell adhesion

Bgee · 19

SKAP1 → anterior pituitary, blood, embryo, granulocyte, islet of Langerhans, left testis, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, pituitary gland, primary oocyte, right adrenal cortex, right lobe of liver, right testis, right uterine tube, secondary oocyte, seminal vesicula, thymus, zygote

RNA expression pattern · 19

related to Interactions · 3

SKAP1 → FYB, FYN, PTPRC

Band · 2

SKAP1 → 11|11 D, 17q21.32

Chr. · 2

SKAP1 → Chromosome 11 (mouse), Chromosome 17 (human)

End · 2

SKAP1 → 48,430,275 bp, 96,649,956 bp

Aliases · 1

SKAP1 → SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1

Available structures · 1

SKAP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D

BioGPS · 1

SKAP1 → More reference expression data

Important terminology Word statistics

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Important terminology

protein gene bp chr human band chromosome 17 adapter encoded mouse adhesion activation location additional src phosphoprotein cell activity domain

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
SKAP1	Aliases	SKAP1, HEL-S-81p, SCAP1, SKAP55, src kinase associated phosphoprotein 1	1.00	infobox
SKAP1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5D	1.00	infobox
SKAP1	Band	17q21.32	1.00	infobox
SKAP1	Band	11\|11 D	1.00	infobox
SKAP1	Bgee	granulocyte	1.00	infobox
SKAP1	Bgee	right lobe of liver	1.00	infobox
SKAP1	Bgee	right uterine tube	1.00	infobox
SKAP1	Bgee	lymph node	1.00	infobox
SKAP1	Bgee	blood	1.00	infobox
SKAP1	Bgee	pituitary gland	1.00	infobox
SKAP1	Bgee	right testis	1.00	infobox
SKAP1	Bgee	left testis	1.00	infobox
SKAP1	Bgee	anterior pituitary	1.00	infobox
SKAP1	Bgee	right adrenal cortex	1.00	infobox
SKAP1	Bgee	thymus	1.00	infobox
SKAP1	Bgee	zygote	1.00	infobox
SKAP1	Bgee	secondary oocyte	1.00	infobox
SKAP1	Bgee	primary oocyte	1.00	infobox
SKAP1	Bgee	mesenteric lymph nodes	1.00	infobox
SKAP1	Bgee	islet of Langerhans	1.00	infobox
SKAP1	Bgee	seminal vesicula	1.00	infobox
SKAP1	Bgee	embryo	1.00	infobox
SKAP1	Bgee	lumbar subsegment of spinal cord	1.00	infobox
SKAP1	BioGPS	More reference expression data	1.00	infobox
SKAP1	Chr.	Chromosome 17 (human)	1.00	infobox
SKAP1	Chr.	Chromosome 11 (mouse)	1.00	infobox
SKAP1	Databases	NCBI: entry; OMA: entry	1.00	infobox
SKAP1	End	48,430,275 bp	1.00	infobox
SKAP1	End	96,649,956 bp	1.00	infobox
SKAP1	Ensembl	ENSG00000141293	1.00	infobox

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