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FYB: Function, Structure & Overview

FYN binding protein (FYB-120/130), also known as FYB, ADAP (Adhesion and degranulation-promoting adapter protein), and SLAP-130 (SLP-76-associated phosphoprotein) is a protein that is encoded by the FYB1 gene in humans (previously FYB). The protein is expressed in T cells, monocytes, mast cells, macrophages, NK cells, but not B cells. FYB is a…

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FYB topic overview

The analysis highlights Function, Structure and Overview as prominent areas in the source structure around FYB.

Related topics
20
Source areas
3
Connected nodes
23
Extracted relationships
96
Concept neighborhoods
14
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 10 topics
Overview · 6 topics
Structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO
Band
5p13.1 · 15|15 A1
Bgee
monocyte · blood · lymph node · bone marrow cell · trabecular bone
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FYB connects Entity context

The extracted context around FYB shows recurring relationship patterns in the source. For example, FYB → actin cytoskeleton, biological process, cell junction, cytoplasm, cytosol, immune response, integrin-mediated signaling pathway, intracellular signal transduction, lipid binding, NLS-bearing protein import into nucleus, nucleus, plasma membrane, protein binding, protein localization to plasma membrane, protein phosphorylation, protein-containing complex binding, signal transduction, signaling receptor binding, T cell receptor signaling pathway Another extracted example is FYB → appendix, blood, bone marrow cell, epithelium of colon, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, monocyte, morula, spermatid, spleen, stroma of bone marrow, thymus, tibiofemoral joint, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.

FYB

Top relations

Gene ontology · 19
FYB → actin cytoskeleton, biological process, cell junction, cytoplasm, cytosol, immune response, integrin-mediated signaling pathway, intracellular signal transduction, lipid binding, NLS-bearing protein import into nucleus, nucleus, plasma membrane, protein binding, protein localization to plasma membrane, protein phosphorylation, protein-containing complex binding, signal transduction, signaling receptor binding, T cell receptor signaling pathway
Bgee · 16
FYB → appendix, blood, bone marrow cell, epithelium of colon, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, monocyte, morula, spermatid, spleen, stroma of bone marrow, thymus, tibiofemoral joint, trabecular bone
RNA expression pattern · 16
FYB → appendix, blood, bone marrow cell, epithelium of colon, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, monocyte, morula, spermatid, spleen, stroma of bone marrow, thymus, tibiofemoral joint, trabecular bone
related to Function · 12
FYB → ADAP, After, Carma1, CD4, CD8, FYN, FYN-ADAP, In, NF-κB, NK, T-helper, TCR
related to Structure · 9
FYB → ENA/VASP, FPPP-motif, FYB-120, FYB-130, N-terminal, SH3, The, The FYB, Two
Band · 2
FYB → 15|15 A1, 5p13.1
Chr. · 2
FYB → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
FYB → 39,274,528 bp, 6,692,794 bp
Aliases · 1
FYB → FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB
Available structures · 1
FYB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein cells bp binding chr human band adhesion gene cell fyn chromosome fyb1 signaling cytokine fyb-120 130 adap expressed actin

FYB relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around FYB. Examples in this analysis include FYB → Aliases → FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB and FYB → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FYBAliasesFYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB1.00infobox
FYBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO1.00infobox
FYBBand5p13.11.00infobox
FYBBand15|15 A11.00infobox
FYBBgeemonocyte1.00infobox
FYBBgeeblood1.00infobox
FYBBgeelymph node1.00infobox
FYBBgeebone marrow cell1.00infobox
FYBBgeetrabecular bone1.00infobox
FYBBgeeappendix1.00infobox
FYBBgeegranulocyte1.00infobox
FYBBgeespleen1.00infobox
FYBBgeeepithelium of colon1.00infobox
FYBBgeeepithelium of nasopharynx1.00infobox
FYBBgeethymus1.00infobox
FYBBgeespermatid1.00infobox
FYBBgeemesenteric lymph nodes1.00infobox
FYBBgeestroma of bone marrow1.00infobox
FYBBgeetibiofemoral joint1.00infobox
FYBBgeemorula1.00infobox
FYBBioGPSMore reference expression data1.00infobox
FYBChr.Chromosome 5 (human)1.00infobox
FYBChr.Chromosome 15 (mouse)1.00infobox
FYBDatabasesNCBI: entry; OMA: entry1.00infobox
FYBEnd39,274,528 bp1.00infobox
FYBEnd6,692,794 bp1.00infobox
FYBEnsemblENSG000000820741.00infobox
FYBEntrez25331.00infobox
FYBExternal IDsOMIM: 602731; MGI: 1346327; GeneCards: FYB11.00infobox
FYBGene location (Human)Gene location (Human)Chr.Chromosome 5 (human)Band5p13.1Start39,105,252 bpEnd39,274,528 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around FYB bring nearby vocabulary together. In this analysis, examples include Protein, Cells and Adhesion. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • FYB
    • Protein
    • Cells
    • Adhesion
    • Cell
    • Fyn
    • Signaling
    • Actin
    • Allows
    • Fyb-120
    • Fyb1
    • Integrin
    • Regulates
  • fyb
    • Protein
    • Cells
    • Adhesion
    • Cell
    • Fyn
    • Signaling
    • Actin
    • Allows
    • Fyb-120
    • Fyb1
    • Integrin
    • Regulates
  • protein
    • Actin
    • Gene
    • Signaling
    • Cells
    • Function
    • Macrophages
    • Remodeling
    • Search
    • Slap-130
    • Expressed
    • Location
    • Chromosome
  • cell adhesion
    • Signaling
    • Cell
    • Actin
    • Regulates
    • Fyb
    • Protein
    • Cells
    • End
    • Function
    • Macrophages
    • Mast
    • Mouse
  • actin remodeling
    • Remodeling
    • Signaling
    • Cell
    • Protein
    • End
    • Function
    • Mouse
    • Search
    • Also
    • Cytokine
    • Expressed
    • Fyb-120
  • ena/vasp protein family
    • Actin
    • Gene
    • Signaling
    • Cells
    • Function
    • Macrophages
    • Remodeling
    • Search
    • Slap-130
    • Expressed
    • Location
    • Chromosome
  • tyrosine-based signaling motifs
    • Cell
    • Binding
    • Actin
    • Protein
    • Fyb
    • End
    • Function
    • Mouse
    • Remodeling
    • Search
    • Cytokine
    • Expressed
  • fyn
    • Slap-130
    • Adap
    • Fyb-120
    • Fyb1
    • Gene
    • Protein
    • Fyb
    • Function
    • Search
    • Allows
    • Also
    • Bind

Connections between topic areas Semantic bridges

For FYB, one of the stronger structural bridges in this analysis connects FYB with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FYBFunction · splits 13 ⟂ 11
FYBOverview · splits 17 ⟂ 7
FYBStructure · splits 19 ⟂ 5

Map overview Semantic statistics

FYB

Nodes24
Edges23
Triples96
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around FYB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FYB · EN edition · Analysis: TopicsToTalkAbout

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