FYB

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Explore the main themes, entities and connections around FYB. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

T-helper cells Chemokine Cytotoxic T cells FYN Carma1

10 related topics

Structure

Isoforms SH3 domains ENA/VASP protein family Tyrosine-based signaling motifs

4 related topics

Overview

SLP-76 Protein Gene Cytokine Cell adhesion

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO
Band: 5p13.1 · 15|15 A1
Bgee: monocyte · blood · lymph node · bone marrow cell · trabecular bone
BioGPS: More reference expression data
Chr.: Chromosome 5 (human) · Chromosome 15 (mouse)

Topics to explore

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Overview

SLP-76 Lymphocyte cytosolic protein 2
Protein
Gene
Cytokine
Cell adhesion
Actin remodeling

Structure

Isoforms Protein isoform
SH3 domains SH3 domain
ENA/VASP protein family Ena/Vasp homology proteins
Tyrosine-based signaling motifs Immunoreceptor tyrosine-based activation motif

Function

Advanced semantic analysis

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Map overview Semantic statistics

Nodes24

Edges23

Triples96

Avg. degree1.92

Density0.083333

Components1

How this topic connects Entity context

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FYB

Top relations

Gene ontology · 19

FYB → actin cytoskeleton, biological process, cell junction, cytoplasm, cytosol, immune response, integrin-mediated signaling pathway, intracellular signal transduction, lipid binding, NLS-bearing protein import into nucleus, nucleus, plasma membrane, protein binding, protein localization to plasma membrane, protein phosphorylation, protein-containing complex binding, signal transduction, signaling receptor binding, T cell receptor signaling pathway

Bgee · 16

FYB → appendix, blood, bone marrow cell, epithelium of colon, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, monocyte, morula, spermatid, spleen, stroma of bone marrow, thymus, tibiofemoral joint, trabecular bone

RNA expression pattern · 16

related to Function · 12

FYB → ADAP, After, Carma1, CD4, CD8, FYN, FYN-ADAP, In, NF-κB, NK, T-helper, TCR

related to Structure · 9

FYB → ENA/VASP, FPPP-motif, FYB-120, FYB-130, N-terminal, SH3, The, The FYB, Two

Band · 2

FYB → 15|15 A1, 5p13.1

Chr. · 2

FYB → Chromosome 15 (mouse), Chromosome 5 (human)

End · 2

FYB → 39,274,528 bp, 6,692,794 bp

Aliases · 1

FYB → FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB

Available structures · 1

FYB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO

Important terminology Word statistics

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Important terminology

protein cells bp binding chr human band adhesion gene cell fyn chromosome fyb1 signaling cytokine fyb-120 130 adap expressed actin

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
FYB	Aliases	FYB1, FYN Binding Protein 1, ADAP, FYB-120/130, SLAP-130, FYB	1.00	infobox
FYB	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RI9, 2GTJ, 2GTO	1.00	infobox
FYB	Band	5p13.1	1.00	infobox
FYB	Band	15\|15 A1	1.00	infobox
FYB	Bgee	monocyte	1.00	infobox
FYB	Bgee	blood	1.00	infobox
FYB	Bgee	lymph node	1.00	infobox
FYB	Bgee	bone marrow cell	1.00	infobox
FYB	Bgee	trabecular bone	1.00	infobox
FYB	Bgee	appendix	1.00	infobox
FYB	Bgee	granulocyte	1.00	infobox
FYB	Bgee	spleen	1.00	infobox
FYB	Bgee	epithelium of colon	1.00	infobox
FYB	Bgee	epithelium of nasopharynx	1.00	infobox
FYB	Bgee	thymus	1.00	infobox
FYB	Bgee	spermatid	1.00	infobox
FYB	Bgee	mesenteric lymph nodes	1.00	infobox
FYB	Bgee	stroma of bone marrow	1.00	infobox
FYB	Bgee	tibiofemoral joint	1.00	infobox
FYB	Bgee	morula	1.00	infobox
FYB	BioGPS	More reference expression data	1.00	infobox
FYB	Chr.	Chromosome 5 (human)	1.00	infobox
FYB	Chr.	Chromosome 15 (mouse)	1.00	infobox
FYB	Databases	NCBI: entry; OMA: entry	1.00	infobox
FYB	End	39,274,528 bp	1.00	infobox
FYB	End	6,692,794 bp	1.00	infobox
FYB	Ensembl	ENSG00000082074	1.00	infobox
FYB	Entrez	2533	1.00	infobox
FYB	External IDs	OMIM: 602731; MGI: 1346327; GeneCards: FYB1	1.00	infobox
FYB	Gene location (Human)	Gene location (Human)Chr.Chromosome 5 (human)Band5p13.1Start39,105,252 bpEnd39,274,528 bp	1.00	infobox

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