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Pleckstrin homology domain

Pleckstrin homology domain (PH domain) or (PHIP) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.

Proteins containing PH domain, Examples & Lipid binding specificity

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Key facts & relationships

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AlphaFold
IPR001849 · PF00169
Available protein structures:
IPR001849 · PF00169
CDD
cd00821
ECOD
220.1.1
InterPro
IPR001849
OPM protein
1pls

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Overview

Lipid binding specificity

Structure

Proteins containing PH domain

Subfamilies

Examples

Advanced semantic analysis

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Map overview Semantic statistics

Pleckstrin homology domain

Nodes295
Edges294
Triples21
Avg. degree1.99
Density0.00678
Components1

How this topic connects Entity context

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Pleckstrin homology domain

Top relations

AlphaFold · 2
Pleckstrin homology domain → IPR001849, PF00169
Available protein structures: · 2
Pleckstrin homology domain → IPR001849, PF00169
CDD · 1
Pleckstrin homology domain → cd00821
ECOD · 1
Pleckstrin homology domain → 220.1.1
InterPro · 1
Pleckstrin homology domain → IPR001849
OPM protein · 1
Pleckstrin homology domain → 1pls
OPM superfamily · 1
Pleckstrin homology domain → 49
PDB · 1
Pleckstrin homology domain → IPR001849 PF00169 (ECOD; PDBsum)
Pfam · 1
Pleckstrin homology domain → PF00169
Pfam clan · 1
Pleckstrin homology domain → CL0266

Important terminology Word statistics

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Important terminology

ph proteins domain domains protein kinase pleckstrin membranes different binding phosphatidylinositol btk interpro within osbp structure containing phosphoinositides function cerevisiae

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Pleckstrin homology domainAlphaFoldIPR0018491.00infobox
Pleckstrin homology domainAlphaFoldPF001691.00infobox
Pleckstrin homology domainAvailable protein structures:IPR0018491.00infobox
Pleckstrin homology domainAvailable protein structures:PF001691.00infobox
Pleckstrin homology domainCDDcd008211.00infobox
Pleckstrin homology domainECOD220.1.11.00infobox
Pleckstrin homology domainInterProIPR0018491.00infobox
Pleckstrin homology domainOPM protein1pls1.00infobox
Pleckstrin homology domainOPM superfamily491.00infobox
Pleckstrin homology domainPDBIPR001849 PF00169 (ECOD; PDBsum)1.00infobox
Pleckstrin homology domainPfamPF001691.00infobox
Pleckstrin homology domainPfam clanCL02661.00infobox
Pleckstrin homology domainPROSITEPDOC500031.00infobox
Pleckstrin homology domainSCOP21dyn / SCOPe / SUPFAM1.00infobox
Pleckstrin homology domainSMARTPH1.00infobox
Pleckstrin homology domainSymbolPH1.00infobox

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