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Septin

Septins are a group of GTP-binding proteins expressed in all eukaryotic cells except plants. Different septins form protein complexes with each other. These complexes can further assemble into filaments, rings and gauzes. Assembled as such, septins function in cells by localizing other proteins, either by providing a scaffold to which proteins can…

History, In filamentous fungi & In animals

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Key facts & relationships

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AlphaFold
IPR000038 · PF00735
Available protein structures:
IPR000038 · PF00735
InterPro
IPR000038
PDB
IPR000038 PF00735 (ECOD; PDBsum)
Pfam
PF00735
Pfam clan
CL0023

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Overview

Structure

Occurrence

In yeast

In filamentous fungi

In animals

In mitochondria

History

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Map overview Semantic statistics

Septin

Nodes142
Edges141
Triples158
Avg. degree1.99
Density0.014085
Components1

How this topic connects Entity context

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Septin

Top relations

related to Human · 29
Septin → Alzheimer's, As, Disruptions, For, In, Microbes, Parkinson's, Potential, SEPT1, SEPT10, SEPT11, SEPT12, SEPT14, SEPT2, SEPT3, SEPT4, SEPT5, SEPT6, SEPT7, SEPT8
related to history · 25
Septin → Despite, DNA, Drosophila, Hartwell, How, Immunofluorescence, In, Instead, Leland, Micrographs, Mutant, Purified, Saccharomyces, ScCDC10, ScCDC11, ScCDC12, ScCDC3, ScCLA4, ScGIN4, ScNAP1
related to Structure · 17
Septin → C-terminal, C-termini, Cdc11-Cdc12-Cdc3-Cdc10-Cdc10-Cdc3-Cdc12-Cdc11, Different, For, GTP-binding, In, Initially, N-terminus, P-Loop-NTPase, Sept2-Sept6-Sept7-Sept3-Sept3-Sept7-Sept6-Sept2, Sept2-Sept6-Sept7-Sept7-Sept6-Sept2, Sept7-Sept6-Sept2-Sept2-Sept6-Sept7, Septin Unique Element, Septins, These, They
related to Ashbya gossypii · 15
Septin → AgCDC10, Agcdc10Δ, AgCDC11A, AgCDC11B, AgCDC12, Agcdc12Δ, AgCDC3, Agcdc3Δ, AgSEP7, AgSep7p-GFP, Due, During, In, Rings, The
related to In yeast · 13
Septin → Cdc10, Cdc11, Cdc12, Cdc3, Five, Mitotic, Saccharomyces, Shs1, Spr28, Spr3, The, There, They
related to Aspergillus nidulans · 10
Septin → Additionally, AnAspAp, AnAspBp, AnAspCp, AnAspDp, AnAspEp, Aspergillus, Five, In, Like
related to Organization · 8
Septin → After, During, FRAP, How, Septins, Structural, The, This
related to Candida albicans · 7
Septin → Candida, Cdc12, Double, Elongated, Newly, The, Without Cdc3
related to Caenorhabditis elegans · 4
Septin → Caenorhabditis, In, Septins, UNC59-UNC61-UNC61-UNC59
related to In mitochondria · 4
Septin → CRMP/CRAM-interacting, It, M-septin, The

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Important terminology

septins cell cells filaments ring form proteins cytokinesis mutants yeast cortex different rings protein bud complexes division structures neck genes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SeptinAlphaFoldIPR0000381.00infobox
SeptinAlphaFoldPF007351.00infobox
SeptinAvailable protein structures:IPR0000381.00infobox
SeptinAvailable protein structures:PF007351.00infobox
SeptinInterProIPR0000381.00infobox
SeptinPDBIPR000038 PF00735 (ECOD; PDBsum)1.00infobox
SeptinPfamPF007351.00infobox
SeptinPfam clanCL00231.00infobox
SeptinSymbolCell_Div_GTP_bd1.00infobox
filamentsinstance ofThese hetero-oligomers in turn form higher-order structures0.80text
rings.Septins form cage-like structures around bacterial pathogensinstance ofThese hetero-oligomers in turn form higher-order structures0.80text
immobilizing harmful microbesinstance ofThese hetero-oligomers in turn form higher-order structures0.80text

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