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PTPRT

Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene.

Regions, Substrates & Expression and function in the developing nervous system

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Substrates

14 related topics

Expression and function in the developing nervous system

9 related topics

Interacting proteins

4 related topics

Function

3 related topics

Key facts & relationships

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3.1.3.48
Aliases
PTPRT, RPTPrho, protein tyrosine phosphatase, receptor type T, protein tyrosine phosphatase receptor type T, RPTP-rho, R-PTP-T
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OOQ
Band
20q12-q13.11 · 2 H2|2 81.91 cM
Bgee
Brodmann area 10 · middle temporal gyrus · Brodmann area 23 · frontal pole · superior frontal gyrus
BioGPS
More reference expression data

Topics to explore

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Overview

Function

Structure

Homophilic binding

Regulation of gene expression

Expression and function in the developing nervous system

Substrates

Interacting proteins

Advanced semantic analysis

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Map overview Semantic statistics

PTPRT

Nodes49
Edges48
Triples152
Avg. degree1.96
Density0.040816
Components1

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PTPRT

Top relations

Gene ontology · 30
PTPRT → alpha-catenin binding, beta-catenin binding, cadherin binding, cell adhesion, cell surface, cellular response to interleukin-6, delta-catenin binding, dephosphorylation, gamma-catenin binding, homophilic cell adhesion via plasma membrane adhesion molecules, hydrolase activity, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of cell migration, negative regulation of receptor signaling pathway via STAT, peptidyl-tyrosine dephosphorylation, peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity, phosphatase activity, phosphoprotein phosphatase activity
related to Regulation of gene expression · 26
PTPRT → AP-2, C/EBP, CdxA, DNA, En-1, Evaluation, GATA-1, GATA-2, GKLF, HoxA3, Ik-2, Msx-1, Myb, NF-1, Oct-1, Pax-4, PTPrho, RE-1, RE1-silencing, REST
related to Structure · 22
PTPRT → A5, Alternative, Comparison, FNIII, Ig-like, III-like, MAM, PCP-2, PTP, PTPkappa, PTPmu, PTPrho, PTPRK, PTPRM, PTPRU, R2B, RPTP, RPTPs, RPTPs PTPmu, The
Bgee · 18
PTPRT → Brodmann area 10, Brodmann area 23, Brodmann area 46, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, dorsal tegmental nucleus, dorsolateral prefrontal cortex, frontal pole, lumbar spinal ganglion, middle temporal gyrus, nucleus of stria terminalis, olfactory bulb, orbitofrontal cortex, piriform cortex, postcentral gyrus, primary visual cortex, superior colliculus, superior frontal gyrus
RNA expression pattern · 18
PTPRT → Brodmann area 10, Brodmann area 23, Brodmann area 46, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, dorsal tegmental nucleus, dorsolateral prefrontal cortex, frontal pole, lumbar spinal ganglion, middle temporal gyrus, nucleus of stria terminalis, olfactory bulb, orbitofrontal cortex, piriform cortex, postcentral gyrus, primary visual cortex, superior colliculus, superior frontal gyrus
related to Expression and function in the developing nervous system · 7
PTPRT → At, INL, Its, PTPrho, Specifically, The, Xenopus
related to Expression and function in cancer · 6
PTPRT → Evaluation, PTPrho, RPTP, RT-PCR, The, The PTPrho
Band · 2
PTPRT → 2 H2|2 81.91 cM, 20q12-q13.11
Chr. · 2
PTPRT → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
PTPRT → 162,503,067 bp, 43,189,970 bp

Important terminology Word statistics

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Important terminology

ptprho tyrosine protein activity phosphatase domain human also cancer gene region catalytic bp function expression chr band cells observed cell

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PTPRT3.1.3.481.00infobox
PTPRTAliasesPTPRT, RPTPrho, protein tyrosine phosphatase, receptor type T, protein tyrosine phosphatase receptor type T, RPTP-rho, R-PTP-T1.00infobox
PTPRTAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OOQ1.00infobox
PTPRTBand20q12-q13.111.00infobox
PTPRTBand2 H2|2 81.91 cM1.00infobox
PTPRTBgeeBrodmann area 101.00infobox
PTPRTBgeemiddle temporal gyrus1.00infobox
PTPRTBgeeBrodmann area 231.00infobox
PTPRTBgeefrontal pole1.00infobox
PTPRTBgeesuperior frontal gyrus1.00infobox
PTPRTBgeeBrodmann area 461.00infobox
PTPRTBgeeprimary visual cortex1.00infobox
PTPRTBgeeorbitofrontal cortex1.00infobox
PTPRTBgeepostcentral gyrus1.00infobox
PTPRTBgeedorsolateral prefrontal cortex1.00infobox
PTPRTBgeepiriform cortex1.00infobox
PTPRTBgeenucleus of stria terminalis1.00infobox
PTPRTBgeecentral gray substance of midbrain1.00infobox
PTPRTBgeelumbar spinal ganglion1.00infobox
PTPRTBgeesuperior colliculus1.00infobox
PTPRTBgeeolfactory bulb1.00infobox
PTPRTBgeedorsal tegmental nucleus1.00infobox
PTPRTBgeedentate gyrus of hippocampal formation granule cell1.00infobox
PTPRTBioGPSMore reference expression data1.00infobox
PTPRTChr.Chromosome 20 (human)1.00infobox
PTPRTChr.Chromosome 2 (mouse)1.00infobox
PTPRTDatabasesNCBI: entry; OMA: entry1.00infobox
PTPRTEnd43,189,970 bp1.00infobox
PTPRTEnd162,503,067 bp1.00infobox
PTPRTEnsemblENSG000001960901.00infobox

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