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Explore the main themes, entities and connections around PTPRK. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Function
8 related topics
Interactions
7 related topics
Structure
3 related topics
Regulation
3 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 3.1.3.48
- ↗
- Aliases
- PTPRK, R-PTP-kappa, protein tyrosine phosphatase, receptor type K, protein tyrosine phosphatase receptor type K
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2C7S
- Band
- 6q22.33 · 10 A4|10 15.06 cM
- Bgee
- corpus callosum · epithelium of colon · gallbladder · duodenum · Achilles tendon
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Function
- Protein tyrosine phosphatase
- Phosphate
- Tyrosine
- Tyrosine kinases Tyrosine kinase
- Oncogenic Carcinogenesis
- Genome
- Type I transmembrane protein
- THEMIS Protein THEMIS
Structure
Regulation
- Glycosylation
- Keratinocytes Keratinocyte
- HaCaT
Clinical significance
Interactions
- Beta-catenin
- E-cadherin
- CDH-1 CDH-1?action=edit&redlink=1
- Epidermal growth factor receptor
- HER2
- Plakoglobin
- Α-catenin
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.PTPRK
Nodes32
Edges31
Triples138
Avg. degree1.94
Density0.0625
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
PTPRK
Top relations
Gene ontology · 40
PTPRK → adherens junction, axon, beta-catenin binding, cell adhesion, cell junction, cell migration, cell surface, cell-cell junction, cellular response to reactive oxygen species, cellular response to UV, dendrite, dephosphorylation, focal adhesion assembly, gamma-catenin binding, hydrolase activity, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, leading edge membrane, membrane
Bgee · 20
PTPRK → Achilles tendon, barrel cortex, ciliary body, corpus callosum, duodenum, epithelium of colon, epithelium of lens, gallbladder, genital tubercle, iris, islet of Langerhans, Paneth cell, rectum, Region I of hippocampus proper, right kidney, stomach, stromal cell of endometrium, superior frontal gyrus, tail of embryo, vestibular membrane of cochlear duct
RNA expression pattern · 20
PTPRK → Achilles tendon, barrel cortex, ciliary body, corpus callosum, duodenum, epithelium of colon, epithelium of lens, gallbladder, genital tubercle, iris, islet of Langerhans, Paneth cell, rectum, Region I of hippocampus proper, right kidney, stomach, stromal cell of endometrium, superior frontal gyrus, tail of embryo, vestibular membrane of cochlear duct
related to Glioma · 7
PTPRK → Assem, Expression, In, LOH, PTPkappa, U251-MG, U87-MG
related to Interactions · 7
PTPRK → Beta-catenin, CDH-1, E-cadherin, EGFR, Epidermal, HER2, Plakoglobin
related to Expression · 5
PTPRK → HaCaT, HER2, PTPkappa, Stimulation, TGFβ1
related to Function · 5
PTPRK → Protein, PTP, PTPs, The, Tyrosine
related to Alternative splicing · 3
PTPRK → Alternative, PTPkappa, Two
Band · 2
PTPRK → 10 A4|10 15.06 cM, 6q22.33
Chr. · 2
PTPRK → Chromosome 10 (mouse), Chromosome 6 (human)
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
ptpkappa cells cell gene expression phosphatase activity tyrosine human protein observed also development egfr proliferation mrna tumor shown bp membrane
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PTPRK | 3.1.3.48 | ↗ | 1.00 | infobox |
| PTPRK | Aliases | PTPRK, R-PTP-kappa, protein tyrosine phosphatase, receptor type K, protein tyrosine phosphatase receptor type K | 1.00 | infobox |
| PTPRK | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2C7S | 1.00 | infobox |
| PTPRK | Band | 6q22.33 | 1.00 | infobox |
| PTPRK | Band | 10 A4|10 15.06 cM | 1.00 | infobox |
| PTPRK | Bgee | corpus callosum | 1.00 | infobox |
| PTPRK | Bgee | epithelium of colon | 1.00 | infobox |
| PTPRK | Bgee | gallbladder | 1.00 | infobox |
| PTPRK | Bgee | duodenum | 1.00 | infobox |
| PTPRK | Bgee | Achilles tendon | 1.00 | infobox |
| PTPRK | Bgee | superior frontal gyrus | 1.00 | infobox |
| PTPRK | Bgee | islet of Langerhans | 1.00 | infobox |
| PTPRK | Bgee | rectum | 1.00 | infobox |
| PTPRK | Bgee | stromal cell of endometrium | 1.00 | infobox |
| PTPRK | Bgee | stomach | 1.00 | infobox |
| PTPRK | Bgee | tail of embryo | 1.00 | infobox |
| PTPRK | Bgee | genital tubercle | 1.00 | infobox |
| PTPRK | Bgee | barrel cortex | 1.00 | infobox |
| PTPRK | Bgee | Paneth cell | 1.00 | infobox |
| PTPRK | Bgee | ciliary body | 1.00 | infobox |
| PTPRK | Bgee | right kidney | 1.00 | infobox |
| PTPRK | Bgee | iris | 1.00 | infobox |
| PTPRK | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| PTPRK | Bgee | epithelium of lens | 1.00 | infobox |
| PTPRK | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| PTPRK | BioGPS | More reference expression data | 1.00 | infobox |
| PTPRK | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| PTPRK | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| PTPRK | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PTPRK | End | 128,520,616 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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