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Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known as PTPkappa and PTPκ.
The analysis highlights Function, Interactions and Regulation as prominent areas in the source structure around PTPRK.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around PTPRK shows recurring relationship patterns in the source. For example, PTPRK → adherens junction, axon, beta-catenin binding, cell adhesion, cell junction, cell migration, cell surface, cell-cell junction, cellular response to reactive oxygen species, cellular response to UV, dendrite, dephosphorylation, focal adhesion assembly, gamma-catenin binding, hydrolase activity, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, leading edge membrane, membrane Another extracted example is PTPRK → Achilles tendon, barrel cortex, ciliary body, corpus callosum, duodenum, epithelium of colon, epithelium of lens, gallbladder, genital tubercle, iris, islet of Langerhans, Paneth cell, rectum, Region I of hippocampus proper, right kidney, stomach, stromal cell of endometrium, superior frontal gyrus, tail of embryo, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.
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ptpkappa cells cell gene expression phosphatase activity tyrosine human protein observed also development egfr proliferation mrna tumor shown bp membrane
TTTA extracted 134 structured relationships around PTPRK. Examples in this analysis include PTPRK → 3.1.3.48 → ↗ and PTPRK → Aliases → PTPRK, R-PTP-kappa, protein tyrosine phosphatase, receptor type K, protein tyrosine phosphatase receptor type K. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PTPRK | 3.1.3.48 | ↗ | 1.00 | infobox |
| PTPRK | Aliases | PTPRK, R-PTP-kappa, protein tyrosine phosphatase, receptor type K, protein tyrosine phosphatase receptor type K | 1.00 | infobox |
| PTPRK | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2C7S | 1.00 | infobox |
| PTPRK | Band | 6q22.33 | 1.00 | infobox |
| PTPRK | Band | 10 A4|10 15.06 cM | 1.00 | infobox |
| PTPRK | Bgee | corpus callosum | 1.00 | infobox |
| PTPRK | Bgee | epithelium of colon | 1.00 | infobox |
| PTPRK | Bgee | gallbladder | 1.00 | infobox |
| PTPRK | Bgee | duodenum | 1.00 | infobox |
| PTPRK | Bgee | Achilles tendon | 1.00 | infobox |
| PTPRK | Bgee | superior frontal gyrus | 1.00 | infobox |
| PTPRK | Bgee | islet of Langerhans | 1.00 | infobox |
| PTPRK | Bgee | rectum | 1.00 | infobox |
| PTPRK | Bgee | stromal cell of endometrium | 1.00 | infobox |
| PTPRK | Bgee | stomach | 1.00 | infobox |
| PTPRK | Bgee | tail of embryo | 1.00 | infobox |
| PTPRK | Bgee | genital tubercle | 1.00 | infobox |
| PTPRK | Bgee | barrel cortex | 1.00 | infobox |
| PTPRK | Bgee | Paneth cell | 1.00 | infobox |
| PTPRK | Bgee | ciliary body | 1.00 | infobox |
| PTPRK | Bgee | right kidney | 1.00 | infobox |
| PTPRK | Bgee | iris | 1.00 | infobox |
| PTPRK | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| PTPRK | Bgee | epithelium of lens | 1.00 | infobox |
| PTPRK | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| PTPRK | BioGPS | More reference expression data | 1.00 | infobox |
| PTPRK | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| PTPRK | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| PTPRK | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PTPRK | End | 128,520,616 bp | 1.00 | infobox |
The concept neighborhoods around PTPRK bring nearby vocabulary together. In this analysis, examples include Observed, Cell and Growth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PTPRK, one of the stronger structural bridges in this analysis connects PTPRK with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PTPRK to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PTPRK · EN edition · Analysis: TopicsToTalkAbout
