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PSMC6: Measurement, Overview & Complex assembly

26S protease regulatory subunit S10B, also known as 26S proteasome AAA-ATPase subunit Rpt4, is an enzyme that in humans is encoded by the PSMC6 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4 (this protein), Rpt5, and Rpt6) together with…

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PSMC6 topic overview

The analysis highlights Measurement, Overview and Complex assembly as prominent areas in the source structure around PSMC6.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
113
Concept neighborhoods
13
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Complex assembly · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PSMC6, CADP44, HEL-S-73, P44, SUG2, p42, proteasome 26S subunit, ATPase 6, RPT5
Band
14q22.1 · 14|14 C1
Bgee
buccal mucosa cell · palpebral conjunctiva · epithelium of nasopharynx · amniotic fluid · tibia
BioGPS
More reference expression data
Chr.
Chromosome 14 (human) · Chromosome 14 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Complex assembly

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PSMC6 connects Entity context

The extracted context around PSMC6 shows recurring relationship patterns in the source. For example, PSMC6 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, cytoplasm, cytosol, cytosolic proteasome complex, extracellular exosome, Fc-epsilon receptor signaling pathway, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nuclear proteasome complex, nucleoplasm, nucleotide binding Another extracted example is PSMC6 → abdominal wall, amniotic fluid, atrioventricular valve, buccal mucosa cell, epiblast, epithelium of nasopharynx, extensor digitorum longus muscle, germinal epithelium, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, olfactory epithelium, oral cavity, otic placode, palpebral conjunctiva, parietal pleura, plantaris muscle, tibia, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

PSMC6

Top relations

Gene ontology · 49
PSMC6 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, cytoplasm, cytosol, cytosolic proteasome complex, extracellular exosome, Fc-epsilon receptor signaling pathway, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nuclear proteasome complex, nucleoplasm, nucleotide binding
Bgee · 20
PSMC6 → abdominal wall, amniotic fluid, atrioventricular valve, buccal mucosa cell, epiblast, epithelium of nasopharynx, extensor digitorum longus muscle, germinal epithelium, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, olfactory epithelium, oral cavity, otic placode, palpebral conjunctiva, parietal pleura, plantaris muscle, tibia, visceral pleura
RNA expression pattern · 20
PSMC6 → abdominal wall, amniotic fluid, atrioventricular valve, buccal mucosa cell, epiblast, epithelium of nasopharynx, extensor digitorum longus muscle, germinal epithelium, mandibular prominence, maxillary prominence, medial ganglionic eminence, mucosa of paranasal sinus, olfactory epithelium, oral cavity, otic placode, palpebral conjunctiva, parietal pleura, plantaris muscle, tibia, visceral pleura
related to Gene · 4
PSMC6 → ATPase, ATPases, Pseudogenes, The
Band · 2
PSMC6 → 14q22.1, 14|14 C1
Chr. · 2
PSMC6 → Chromosome 14 (human), Chromosome 14 (mouse)
End · 2
PSMC6 → 45,587,162 bp, 52,728,590 bp
Aliases · 1
PSMC6 → PSMC6, CADP44, HEL-S-73, P44, SUG2, p42, proteasome 26S subunit, ATPase 6, RPT5
BioGPS · 1
PSMC6 → More reference expression data
Databases · 1
PSMC6 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

19s regulatory protein subunits complex proteasome particle gene subunit 26s human bp base band rpt5 chr chromosome rpn13 assembly 20s

PSMC6 relationships Subject–Predicate–Object triples

TTTA extracted 113 structured relationships around PSMC6. Examples in this analysis include PSMC6 → Aliases → PSMC6, CADP44, HEL-S-73, P44, SUG2, p42, proteasome 26S subunit, ATPase 6, RPT5 and PSMC6 → Band → 14q22.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PSMC6AliasesPSMC6, CADP44, HEL-S-73, P44, SUG2, p42, proteasome 26S subunit, ATPase 6, RPT51.00infobox
PSMC6Band14q22.11.00infobox
PSMC6Band14|14 C11.00infobox
PSMC6Bgeebuccal mucosa cell1.00infobox
PSMC6Bgeepalpebral conjunctiva1.00infobox
PSMC6Bgeeepithelium of nasopharynx1.00infobox
PSMC6Bgeeamniotic fluid1.00infobox
PSMC6Bgeetibia1.00infobox
PSMC6Bgeegerminal epithelium1.00infobox
PSMC6Bgeevisceral pleura1.00infobox
PSMC6Bgeeparietal pleura1.00infobox
PSMC6Bgeemucosa of paranasal sinus1.00infobox
PSMC6Bgeeoral cavity1.00infobox
PSMC6Bgeeatrioventricular valve1.00infobox
PSMC6Bgeemandibular prominence1.00infobox
PSMC6Bgeemaxillary prominence1.00infobox
PSMC6Bgeeabdominal wall1.00infobox
PSMC6Bgeeotic placode1.00infobox
PSMC6Bgeeolfactory epithelium1.00infobox
PSMC6Bgeeextensor digitorum longus muscle1.00infobox
PSMC6Bgeeplantaris muscle1.00infobox
PSMC6Bgeemedial ganglionic eminence1.00infobox
PSMC6Bgeeepiblast1.00infobox
PSMC6BioGPSMore reference expression data1.00infobox
PSMC6Chr.Chromosome 14 (human)1.00infobox
PSMC6Chr.Chromosome 14 (mouse)1.00infobox
PSMC6DatabasesNCBI: entry; OMA: entry1.00infobox
PSMC6End52,728,590 bp1.00infobox
PSMC6End45,587,162 bp1.00infobox
PSMC6EnsemblENSG000001005191.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PSMC6 bring nearby vocabulary together. In this analysis, examples include Chromosome, Human and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • proteasome
    • One
    • Complex
    • Atpase
    • Psmc6
    • Rpt5
    • Regulatory
    • Subunits
    • Subunit
    • Location
    • Rpn10
    • Rpt4
    • Particle
  • complex assembly
    • Base
    • Sub
    • Proteasome
    • Assembly
    • Complex
    • Location
    • Atpase
    • Psmc6
    • Protein
    • One
    • Bp
    • Chr
  • gene
    • Psmc6
    • Chromosome
    • Location
    • Human
    • Band
    • Bp
    • Chr
    • Proteasome
    • Atpase
    • Assembly
    • Subunit
    • Complex
  • PSMC6
    • Chromosome
    • Human
    • Location
    • Atpase
    • Assembly
    • Band
    • Bp
    • Chr
    • Subunit
    • One
    • Rpt4
    • Complex
  • psmc6
    • Chromosome
    • Human
    • Location
    • Atpase
    • Assembly
    • Band
    • Bp
    • Chr
    • Subunit
    • One
    • Rpt4
    • Complex
  • rpt5
    • Rpt6
    • Rpn10
    • Subunit
    • Atpase
    • Rpn13
    • Subunits
    • Location
    • Rpn1
    • Atpases
    • Cp
    • Ring
    • Sub
  • rpt1
    • Rpt3
    • Rpt6
    • Rpt2
    • Rpt5
    • Rpt4
    • Rpn1
    • Rpn10
    • Atpases
    • Cp
    • Ring
    • Rpn13
    • Sub
  • rpt2
    • Rpt3
    • Rpt6
    • Rpt5
    • Rpt4
    • Subunit
    • Rpn1
    • Rpn10
    • Atpases
    • Cp
    • Ring
    • Rpn13
    • Sub

Connections between topic areas Semantic bridges

For PSMC6, one of the stronger structural bridges in this analysis connects PSMC6 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PSMC6Overview · splits 4 ⟂ 13
PSMC6Complex assembly · splits 14 ⟂ 3

Map overview Semantic statistics

PSMC6

Nodes17
Edges16
Triples113
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around PSMC6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Overview & Complex assembly, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PSMC6 · EN edition · Analysis: TopicsToTalkAbout

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