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PSMC3

26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4, Rpt5 (this protein), and Rpt6) together with…

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12 related topics

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2 related topics

Complex assembly

1 related topics

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Aliases
PSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP
Band
11p11.2 · 2 E1|2 50.44 cM
Bgee
apex of heart · gastrocnemius muscle · muscle of thigh · islet of Langerhans · ganglionic eminence
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Complex assembly

  • Rpn13 ARDM1?action=edit&redlink=1

Interactions

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Map overview Semantic statistics

PSMC3

Nodes19
Edges18
Triples123
Avg. degree1.89
Density0.105263
Components1

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PSMC3

Top relations

Gene ontology · 55
PSMC3 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, blastocyst development, cytoplasm, cytosol, cytosolic proteasome complex, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, modulation by host of viral transcription, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation
Bgee · 20
PSMC3 → Achilles tendon, apex of heart, caudate nucleus, dentate gyrus of hippocampal formation granule cell, endocardial cushion, endothelial cell of lymphatic vessel, ganglionic eminence, gastrocnemius muscle, islet of Langerhans, lens, mandibular prominence, maxillary prominence, muscle of thigh, popliteal artery, right auricle of heart, seminiferous tubule, spermatid, spermatocyte, tibial arteries, yolk sac
RNA expression pattern · 20
PSMC3 → Achilles tendon, apex of heart, caudate nucleus, dentate gyrus of hippocampal formation granule cell, endocardial cushion, endothelial cell of lymphatic vessel, ganglionic eminence, gastrocnemius muscle, islet of Langerhans, lens, mandibular prominence, maxillary prominence, muscle of thigh, popliteal artery, right auricle of heart, seminiferous tubule, spermatid, spermatocyte, tibial arteries, yolk sac
related to Gene · 6
PSMC3 → ATPase, ATPases, HIV, PSMC2, The, This
Band · 2
PSMC3 → 11p11.2, 2 E1|2 50.44 cM
Chr. · 2
PSMC3 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
PSMC3 → 47,426,473 bp, 90,896,714 bp
related to Interactions · 2
PSMC3 → PSMC5, Von Hippel-Lindau
Aliases · 1
PSMC3 → PSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP
BioGPS · 1
PSMC3 → More reference expression data

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Important terminology

protein 19s regulatory complex subunits proteasome particle subunit gene 26s human bp base rpt5 band chromosome chr rpn13 assembly 20s

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PSMC3AliasesPSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP1.00infobox
PSMC3Band11p11.21.00infobox
PSMC3Band2 E1|2 50.44 cM1.00infobox
PSMC3Bgeeapex of heart1.00infobox
PSMC3Bgeegastrocnemius muscle1.00infobox
PSMC3Bgeemuscle of thigh1.00infobox
PSMC3Bgeeislet of Langerhans1.00infobox
PSMC3Bgeeganglionic eminence1.00infobox
PSMC3Bgeepopliteal artery1.00infobox
PSMC3Bgeetibial arteries1.00infobox
PSMC3Bgeecaudate nucleus1.00infobox
PSMC3BgeeAchilles tendon1.00infobox
PSMC3Bgeeright auricle of heart1.00infobox
PSMC3Bgeespermatid1.00infobox
PSMC3Bgeespermatocyte1.00infobox
PSMC3Bgeeseminiferous tubule1.00infobox
PSMC3Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PSMC3Bgeeendocardial cushion1.00infobox
PSMC3Bgeemandibular prominence1.00infobox
PSMC3Bgeeyolk sac1.00infobox
PSMC3Bgeemaxillary prominence1.00infobox
PSMC3Bgeelens1.00infobox
PSMC3Bgeeendothelial cell of lymphatic vessel1.00infobox
PSMC3BioGPSMore reference expression data1.00infobox
PSMC3Chr.Chromosome 11 (human)1.00infobox
PSMC3Chr.Chromosome 2 (mouse)1.00infobox
PSMC3DatabasesNCBI: entry; OMA: entry1.00infobox
PSMC3End47,426,473 bp1.00infobox
PSMC3End90,896,714 bp1.00infobox
PSMC3EnsemblENSG000001659161.00infobox

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