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PSMC3: Measurement, Overview & Interactions

26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4, Rpt5 (this protein), and Rpt6) together with…

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PSMC3 topic overview

The analysis highlights Measurement, Overview and Interactions as prominent areas in the source structure around PSMC3.

Related topics
15
Source areas
3
Connected nodes
18
Extracted relationships
123
Concept neighborhoods
12
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Interactions · 2 topics
Complex assembly · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP
Band
11p11.2 · 2 E1|2 50.44 cM
Bgee
apex of heart · gastrocnemius muscle · muscle of thigh · islet of Langerhans · ganglionic eminence
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Complex assembly

  • Rpn13 ARDM1?action=edit&redlink=1

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PSMC3 connects Entity context

The extracted context around PSMC3 shows recurring relationship patterns in the source. For example, PSMC3 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, blastocyst development, cytoplasm, cytosol, cytosolic proteasome complex, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, modulation by host of viral transcription, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation Another extracted example is PSMC3 → Achilles tendon, apex of heart, caudate nucleus, dentate gyrus of hippocampal formation granule cell, endocardial cushion, endothelial cell of lymphatic vessel, ganglionic eminence, gastrocnemius muscle, islet of Langerhans, lens, mandibular prominence, maxillary prominence, muscle of thigh, popliteal artery, right auricle of heart, seminiferous tubule, spermatid, spermatocyte, tibial arteries, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

PSMC3

Top relations

Gene ontology · 55
PSMC3 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, blastocyst development, cytoplasm, cytosol, cytosolic proteasome complex, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, modulation by host of viral transcription, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation
Bgee · 20
PSMC3 → Achilles tendon, apex of heart, caudate nucleus, dentate gyrus of hippocampal formation granule cell, endocardial cushion, endothelial cell of lymphatic vessel, ganglionic eminence, gastrocnemius muscle, islet of Langerhans, lens, mandibular prominence, maxillary prominence, muscle of thigh, popliteal artery, right auricle of heart, seminiferous tubule, spermatid, spermatocyte, tibial arteries, yolk sac
RNA expression pattern · 20
PSMC3 → Achilles tendon, apex of heart, caudate nucleus, dentate gyrus of hippocampal formation granule cell, endocardial cushion, endothelial cell of lymphatic vessel, ganglionic eminence, gastrocnemius muscle, islet of Langerhans, lens, mandibular prominence, maxillary prominence, muscle of thigh, popliteal artery, right auricle of heart, seminiferous tubule, spermatid, spermatocyte, tibial arteries, yolk sac
related to Gene · 6
PSMC3 → ATPase, ATPases, HIV, PSMC2, The, This
Band · 2
PSMC3 → 11p11.2, 2 E1|2 50.44 cM
Chr. · 2
PSMC3 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
PSMC3 → 47,426,473 bp, 90,896,714 bp
related to Interactions · 2
PSMC3 → PSMC5, Von Hippel-Lindau
Aliases · 1
PSMC3 → PSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP
BioGPS · 1
PSMC3 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein 19s regulatory complex subunits proteasome particle subunit gene 26s human bp base rpt5 band chromosome chr rpn13 assembly 20s

PSMC3 relationships Subject–Predicate–Object triples

TTTA extracted 123 structured relationships around PSMC3. Examples in this analysis include PSMC3 → Aliases → PSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP and PSMC3 → Band → 11p11.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PSMC3AliasesPSMC3, TBP1, proteasome 26S subunit, ATPase 3, RPT5, DCIDP1.00infobox
PSMC3Band11p11.21.00infobox
PSMC3Band2 E1|2 50.44 cM1.00infobox
PSMC3Bgeeapex of heart1.00infobox
PSMC3Bgeegastrocnemius muscle1.00infobox
PSMC3Bgeemuscle of thigh1.00infobox
PSMC3Bgeeislet of Langerhans1.00infobox
PSMC3Bgeeganglionic eminence1.00infobox
PSMC3Bgeepopliteal artery1.00infobox
PSMC3Bgeetibial arteries1.00infobox
PSMC3Bgeecaudate nucleus1.00infobox
PSMC3BgeeAchilles tendon1.00infobox
PSMC3Bgeeright auricle of heart1.00infobox
PSMC3Bgeespermatid1.00infobox
PSMC3Bgeespermatocyte1.00infobox
PSMC3Bgeeseminiferous tubule1.00infobox
PSMC3Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PSMC3Bgeeendocardial cushion1.00infobox
PSMC3Bgeemandibular prominence1.00infobox
PSMC3Bgeeyolk sac1.00infobox
PSMC3Bgeemaxillary prominence1.00infobox
PSMC3Bgeelens1.00infobox
PSMC3Bgeeendothelial cell of lymphatic vessel1.00infobox
PSMC3BioGPSMore reference expression data1.00infobox
PSMC3Chr.Chromosome 11 (human)1.00infobox
PSMC3Chr.Chromosome 2 (mouse)1.00infobox
PSMC3DatabasesNCBI: entry; OMA: entry1.00infobox
PSMC3End47,426,473 bp1.00infobox
PSMC3End90,896,714 bp1.00infobox
PSMC3EnsemblENSG000001659161.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PSMC3 bring nearby vocabulary together. In this analysis, examples include Chromosome, Human and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • proteasome
    • Rpt5
    • One
    • Atpase
    • Complex
    • Psmc3
    • Regulatory
    • Subunits
    • Location
    • Rpn10
    • Subunit
    • Particle
    • Rpn13
  • complex assembly
    • Base
    • Location
    • Proteasome
    • Sub
    • Protein
    • Assembly
    • Complex
    • Atpase
    • Bp
    • Chr
    • Gene
    • One
  • gene
    • Psmc3
    • Location
    • Chromosome
    • Human
    • Band
    • Bp
    • Chr
    • Proteasome
    • Atpase
    • Assembly
    • Rpt5
    • Subunit
  • PSMC3
    • Chromosome
    • Human
    • Location
    • Atpase
    • Assembly
    • Band
    • Bp
    • Chr
    • Rpt5
    • Subunit
    • One
    • Complex
  • psmc3
    • Chromosome
    • Human
    • Location
    • Atpase
    • Assembly
    • Band
    • Bp
    • Chr
    • Rpt5
    • Subunit
    • One
    • Complex
  • rpt1
    • Rpt3
    • Rpt6
    • Rpt2
    • Rpt5
    • Rpn1
    • Rpn10
    • Atpases
    • Cp
    • Ring
    • Rpn13
    • Sub
    • Subunits
  • rpt2
    • Rpt3
    • Rpt6
    • Rpt5
    • Subunit
    • Rpn1
    • Rpn10
    • Atpases
    • Cp
    • Ring
    • Rpn13
    • Sub
    • Subunits
  • rpn1
    • Rpn10
    • Ring
    • Rpn13
    • Rpt1
    • Rpt3
    • Rpt6
    • Atpases
    • Rpt2
    • Sub
    • Three
    • Subunits
    • Rpt5

Connections between topic areas Semantic bridges

For PSMC3, one of the stronger structural bridges in this analysis connects PSMC3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PSMC3Overview · splits 6 ⟂ 13
PSMC3Interactions · splits 16 ⟂ 3

Map overview Semantic statistics

PSMC3

Nodes19
Edges18
Triples123
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around PSMC3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Overview & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PSMC3 · EN edition · Analysis: TopicsToTalkAbout

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