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Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans. It is one of four identified EP receptors, the others being EP1, EP2, and EP3, all of which bind with and mediate cellular responses to PGE2 and also, but generally with lesser affinity and responsiveness, certain other…
The analysis highlights Expression, Mechanism of cell activation and Functions as prominent areas in the source structure around Prostaglandin EP4 receptor.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A focused starting point derived from the topic graph, ranked independently of the source article order.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Prostaglandin EP4 receptor shows recurring relationship patterns in the source. For example, Prostaglandin EP4 receptor → adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, bone development, cellular response to mechanical stimulus, cellular response to prostaglandin E stimulus, ERK1 and ERK2 cascade, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, immune response, inflammatory response, integral component of membrane, intracellular anatomical structure, JNK cascade, membrane, negative regulation of eosinophil extravasation, negative regulation of inflammatory response, negative regulation of integrin activation, plasma membrane, positive regulation of cytosolic calcium ion concentration, positive regulation of inflammatory response Another extracted example is Prostaglandin EP4 receptor → atrioventricular valve, blood, bronchial epithelial cell, conjunctival fornix, germinal epithelium, glomerulus, hair follicle, ileum, jejunal mucosa, left colon, mesenteric lymph nodes, metanephric glomerulus, mucosa of sigmoid colon, palpebral conjunctiva, Paneth cell, parietal pleura, renal corpuscle, synovial joint, uterus, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
ep4 receptor gene mice activation human cells prostaglandin studies also ptger4 pge2 humans ductus development cell selective disease may receptors
TTTA extracted 102 structured relationships around Prostaglandin EP4 receptor. Examples in this analysis include Prostaglandin EP4 receptor → Aliases → PTGER4, EP4, EP4R, EP4 receptor, prostaglandin E receptor 4 and Prostaglandin EP4 receptor → Band → 5p13.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Prostaglandin EP4 receptor | Aliases | PTGER4, EP4, EP4R, EP4 receptor, prostaglandin E receptor 4 | 1.00 | infobox |
| Prostaglandin EP4 receptor | Band | 5p13.1 | 1.00 | infobox |
| Prostaglandin EP4 receptor | Band | 15 A1|15 1.99 cM | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | palpebral conjunctiva | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | jejunal mucosa | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | glomerulus | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | metanephric glomerulus | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | bronchial epithelial cell | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | visceral pleura | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | synovial joint | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | germinal epithelium | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | parietal pleura | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | renal corpuscle | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | hair follicle | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | conjunctival fornix | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | atrioventricular valve | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | blood | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | uterus | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | Paneth cell | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | left colon | 1.00 | infobox |
| Prostaglandin EP4 receptor | Bgee | ileum | 1.00 | infobox |
| Prostaglandin EP4 receptor | BioGPS | n/a | 1.00 | infobox |
| Prostaglandin EP4 receptor | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| Prostaglandin EP4 receptor | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| Prostaglandin EP4 receptor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Prostaglandin EP4 receptor | End | 40,693,735 bp | 1.00 | infobox |
| Prostaglandin EP4 receptor | End | 5,273,668 bp | 1.00 | infobox |
| Prostaglandin EP4 receptor | Ensembl | ENSG00000171522 | 1.00 | infobox |
The concept neighborhoods around Prostaglandin EP4 receptor bring nearby vocabulary together. In this analysis, examples include See, Also and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Prostaglandin EP4 receptor, one of the stronger structural bridges in this analysis connects Prostaglandin EP4 receptor with Functions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Prostaglandin EP4 receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Expression, Mechanism of cell activation & Functions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Prostaglandin EP4 receptor · EN edition · Analysis: TopicsToTalkAbout