Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Prostaglandin EP4 receptor

Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans. It is one of four identified EP receptors, the others being EP1, EP2, and EP3, all of which bind with and mediate cellular responses to PGE2 and also, but generally with lesser affinity and responsiveness, certain other…

Explore topics related to Prostaglandin EP4 receptor — including Expression, Mechanism of cell activation & Functions.

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Prostaglandin EP4 receptor. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PTGER4, EP4, EP4R, EP4 receptor, prostaglandin E receptor 4
Band
5p13.1 · 15 A1|15 1.99 cM
Bgee
palpebral conjunctiva · jejunal mucosa · glomerulus · mucosa of sigmoid colon · metanephric glomerulus
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Gene

Expression

Ligands

Mechanism of cell activation

Functions

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Prostaglandin EP4 receptor

Nodes143
Edges142
Triples102
Avg. degree1.99
Density0.013986
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Prostaglandin EP4 receptor

Top relations

Gene ontology · 30
Prostaglandin EP4 receptor → adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, bone development, cellular response to mechanical stimulus, cellular response to prostaglandin E stimulus, ERK1 and ERK2 cascade, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, immune response, inflammatory response, integral component of membrane, intracellular anatomical structure, JNK cascade, membrane, negative regulation of eosinophil extravasation, negative regulation of inflammatory response, negative regulation of integrin activation, plasma membrane, positive regulation of cytosolic calcium ion concentration, positive regulation of inflammatory response
Bgee · 20
Prostaglandin EP4 receptor → atrioventricular valve, blood, bronchial epithelial cell, conjunctival fornix, germinal epithelium, glomerulus, hair follicle, ileum, jejunal mucosa, left colon, mesenteric lymph nodes, metanephric glomerulus, mucosa of sigmoid colon, palpebral conjunctiva, Paneth cell, parietal pleura, renal corpuscle, synovial joint, uterus, visceral pleura
RNA expression pattern · 20
Prostaglandin EP4 receptor → atrioventricular valve, blood, bronchial epithelial cell, conjunctival fornix, germinal epithelium, glomerulus, hair follicle, ileum, jejunal mucosa, left colon, mesenteric lymph nodes, metanephric glomerulus, mucosa of sigmoid colon, palpebral conjunctiva, Paneth cell, parietal pleura, renal corpuscle, synovial joint, uterus, visceral pleura
Band · 2
Prostaglandin EP4 receptor → 15 A1|15 1.99 cM, 5p13.1
Chr. · 2
Prostaglandin EP4 receptor → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
Prostaglandin EP4 receptor → 40,693,735 bp, 5,273,668 bp
Aliases · 1
Prostaglandin EP4 receptor → PTGER4, EP4, EP4R, EP4 receptor, prostaglandin E receptor 4
BioGPS · 1
Prostaglandin EP4 receptor → n/a
Databases · 1
Prostaglandin EP4 receptor → NCBI: entry; OMA: entry
Ensembl · 1
Prostaglandin EP4 receptor → ENSG00000171522

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ep4 receptor gene mice activation human cells prostaglandin studies also ptger4 pge2 humans ductus development cell selective disease may receptors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Prostaglandin EP4 receptorAliasesPTGER4, EP4, EP4R, EP4 receptor, prostaglandin E receptor 41.00infobox
Prostaglandin EP4 receptorBand5p13.11.00infobox
Prostaglandin EP4 receptorBand15 A1|15 1.99 cM1.00infobox
Prostaglandin EP4 receptorBgeepalpebral conjunctiva1.00infobox
Prostaglandin EP4 receptorBgeejejunal mucosa1.00infobox
Prostaglandin EP4 receptorBgeeglomerulus1.00infobox
Prostaglandin EP4 receptorBgeemucosa of sigmoid colon1.00infobox
Prostaglandin EP4 receptorBgeemetanephric glomerulus1.00infobox
Prostaglandin EP4 receptorBgeebronchial epithelial cell1.00infobox
Prostaglandin EP4 receptorBgeevisceral pleura1.00infobox
Prostaglandin EP4 receptorBgeesynovial joint1.00infobox
Prostaglandin EP4 receptorBgeegerminal epithelium1.00infobox
Prostaglandin EP4 receptorBgeeparietal pleura1.00infobox
Prostaglandin EP4 receptorBgeerenal corpuscle1.00infobox
Prostaglandin EP4 receptorBgeehair follicle1.00infobox
Prostaglandin EP4 receptorBgeeconjunctival fornix1.00infobox
Prostaglandin EP4 receptorBgeeatrioventricular valve1.00infobox
Prostaglandin EP4 receptorBgeeblood1.00infobox
Prostaglandin EP4 receptorBgeemesenteric lymph nodes1.00infobox
Prostaglandin EP4 receptorBgeeuterus1.00infobox
Prostaglandin EP4 receptorBgeePaneth cell1.00infobox
Prostaglandin EP4 receptorBgeeleft colon1.00infobox
Prostaglandin EP4 receptorBgeeileum1.00infobox
Prostaglandin EP4 receptorBioGPSn/a1.00infobox
Prostaglandin EP4 receptorChr.Chromosome 5 (human)1.00infobox
Prostaglandin EP4 receptorChr.Chromosome 15 (mouse)1.00infobox
Prostaglandin EP4 receptorDatabasesNCBI: entry; OMA: entry1.00infobox
Prostaglandin EP4 receptorEnd40,693,735 bp1.00infobox
Prostaglandin EP4 receptorEnd5,273,668 bp1.00infobox
Prostaglandin EP4 receptorEnsemblENSG000001715221.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.

    Researching Prostaglandin EP4 receptor? Use this map to explore Expression, Mechanism of cell activation & Functions and other closely related topics, then follow useful entities and relationships into deeper research. Automatically generated connections are research leads, so verify important facts in reliable sources.