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In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell–cell and cell–matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring…
The analysis highlights Regions, Binding site and Splice variants as prominent areas in the source structure around Vinculin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Vinculin shows recurring relationship patterns in the source. For example, Vinculin → actin binding, actin cytoskeleton, adherens junction, adherens junction assembly, alpha-catenin binding, apical junction assembly, axon extension, beta-catenin binding, brush border, cadherin binding, cell adhesion, cell junction, cell-cell junction, cell-matrix adhesion, cell-substrate junction, costamere, cytoplasm, cytoskeleton, cytosol, dystroglycan binding Another extracted example is Vinculin → ascending aorta, calvaria, carotid body, Descending thoracic aorta, endothelial cell of lymphatic vessel, left lung, left lung lobe, nipple, popliteal artery, right coronary artery, right lung, saphenous vein, seminal vesicula, smooth muscle tissue, tibial arteries, tibiofemoral joint, tunica media of zone of aorta, umbilical cord, urethra, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
binding talin focal actin adhesion protein function bp human cytoskeleton cell chr band tail membrane gene α-actinin domain head metavinculin
TTTA extracted 167 structured relationships around Vinculin. Examples in this analysis include Vinculin → Aliases → VCL, CMD1W, CMH15, HEL114, MV, Mvinculin and Vinculin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RKC, 1RKE, 1SYQ, 1TR2, 2GWW, 2IBF, 3H2U, 3H2V, 3MYI, 3TJ5, 3TJ6, 3VF0, 4DJ9, 4EHP, 1YDI, 2HSQ, 3RF3, 3S90,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Vinculin | Aliases | VCL, CMD1W, CMH15, HEL114, MV, Mvinculin | 1.00 | infobox |
| Vinculin | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RKC, 1RKE, 1SYQ, 1TR2, 2GWW, 2IBF, 3H2U, 3H2V, 3MYI, 3TJ5, 3TJ6, 3VF0, 4DJ9, 4EHP, 1YDI, 2HSQ, 3RF3, 3S90,… | 1.00 | infobox |
| Vinculin | Band | 10q22.2 | 1.00 | infobox |
| Vinculin | Band | 14 A3|14 11.53 cM | 1.00 | infobox |
| Vinculin | Bgee | saphenous vein | 1.00 | infobox |
| Vinculin | Bgee | urethra | 1.00 | infobox |
| Vinculin | Bgee | vena cava | 1.00 | infobox |
| Vinculin | Bgee | smooth muscle tissue | 1.00 | infobox |
| Vinculin | Bgee | right coronary artery | 1.00 | infobox |
| Vinculin | Bgee | popliteal artery | 1.00 | infobox |
| Vinculin | Bgee | tibial arteries | 1.00 | infobox |
| Vinculin | Bgee | nipple | 1.00 | infobox |
| Vinculin | Bgee | seminal vesicula | 1.00 | infobox |
| Vinculin | Bgee | Descending thoracic aorta | 1.00 | infobox |
| Vinculin | Bgee | tunica media of zone of aorta | 1.00 | infobox |
| Vinculin | Bgee | calvaria | 1.00 | infobox |
| Vinculin | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Vinculin | Bgee | tibiofemoral joint | 1.00 | infobox |
| Vinculin | Bgee | umbilical cord | 1.00 | infobox |
| Vinculin | Bgee | ascending aorta | 1.00 | infobox |
| Vinculin | Bgee | right lung | 1.00 | infobox |
| Vinculin | Bgee | left lung | 1.00 | infobox |
| Vinculin | Bgee | carotid body | 1.00 | infobox |
| Vinculin | Bgee | left lung lobe | 1.00 | infobox |
| Vinculin | BioGPS | More reference expression data | 1.00 | infobox |
| Vinculin | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Vinculin | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| Vinculin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Vinculin | End | 74,121,363 bp | 1.00 | infobox |
| Vinculin | End | 21,083,744 bp | 1.00 | infobox |
The concept neighborhoods around Vinculin bring nearby vocabulary together. In this analysis, examples include Α-actinin, State and Tail. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Vinculin, one of the stronger structural bridges in this analysis connects Vinculin with Binding site. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Vinculin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Binding site & Splice variants, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Vinculin · EN edition · Analysis: TopicsToTalkAbout