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Research this topic
Explore the main themes, entities and connections around Vinculin. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Binding site
11 related topics
Splice variants
10 related topics
Structure
8 related topics
Mechanism and function
7 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- VCL, CMD1W, CMH15, HEL114, MV, Mvinculin
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RKC, 1RKE, 1SYQ, 1TR2, 2GWW, 2IBF, 3H2U, 3H2V, 3MYI, 3TJ5, 3TJ6, 3VF0, 4DJ9, 4EHP, 1YDI, 2HSQ, 3RF3, 3S90,…
- Band
- 10q22.2 · 14 A3|14 11.53 cM
- Bgee
- saphenous vein · urethra · vena cava · smooth muscle tissue · right coronary artery
- BioGPS
- More reference expression data
- Chr.
- Chromosome 10 (human) · Chromosome 14 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Structure
- Amino acids
- N-terminal
- C-terminal C-terminus
- Proline
- Talin Talin (protein)
- Α-actinin
- Paxillin
- Lipids
Mechanism and function
Activation
Binding site
- Binding sites Binding site
- Binding Molecular binding
- Integrins
- Consensus sequence
- Binding sites Active site
- Secondary structure
- Amphipathic
- Helices Alpha helix
- Hydrophobic
- Residues Residue (chemistry)
- Helical Helix
Splice variants
- Smooth muscles Smooth muscle
- Skeletal muscles Skeletal muscle
- Cardiac muscle
- Differentiated Cellular differentiation
- Splice variant
- Exon
- Cardiomyopathy
- Intercalated discs Intercalated disc
- Cardiomyocytes Cardiomyocyte
- Costameres Costamere
Interactions
- Interact Protein-protein interaction
- CDH1 CDH1 (gene)
- SORBS1
- Small intestinal bacterial overgrowth
- IBS Irritable bowel syndrome
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.Vinculin
Nodes60
Edges59
Triples167
Avg. degree1.97
Density0.033333
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
Vinculin
Top relations
Gene ontology · 50
Vinculin → actin binding, actin cytoskeleton, adherens junction, adherens junction assembly, alpha-catenin binding, apical junction assembly, axon extension, beta-catenin binding, brush border, cadherin binding, cell adhesion, cell junction, cell-cell junction, cell-matrix adhesion, cell-substrate junction, costamere, cytoplasm, cytoskeleton, cytosol, dystroglycan binding
Bgee · 20
Vinculin → ascending aorta, calvaria, carotid body, Descending thoracic aorta, endothelial cell of lymphatic vessel, left lung, left lung lobe, nipple, popliteal artery, right coronary artery, right lung, saphenous vein, seminal vesicula, smooth muscle tissue, tibial arteries, tibiofemoral joint, tunica media of zone of aorta, umbilical cord, urethra, vena cava
RNA expression pattern · 20
Vinculin → ascending aorta, calvaria, carotid body, Descending thoracic aorta, endothelial cell of lymphatic vessel, left lung, left lung lobe, nipple, popliteal artery, right coronary artery, right lung, saphenous vein, seminal vesicula, smooth muscle tissue, tibial arteries, tibiofemoral joint, tunica media of zone of aorta, umbilical cord, urethra, vena cava
related to Splice variants · 11
Vinculin → Both, C-terminal, Compared, II, In, Metavinculin, Mutations, Smooth, The, Translation, VCL
related to External links · 8
Vinculin → Human Vinculin, Mouse Vinculin, Overview, P18206, PDB, PDBe-KB, Q64727, UniProt
related to Structure · 6
Vinculin → C-terminal, Essentially, F-actin, N-terminal, The, This
related to Activation · 5
Vinculin → PIP2, The, These, This, When
related to Binding site · 4
Vinculin → LxxAAxxVAxxVxxLIxxA, Talin, The, VBS
related to Mechanism and function · 4
Vinculin → Cell, In, The, These
Band · 2
Vinculin → 10q22.2, 14 A3|14 11.53 cM
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
binding talin focal actin adhesion protein function bp human cytoskeleton cell chr band tail membrane gene α-actinin domain head metavinculin
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Vinculin | Aliases | VCL, CMD1W, CMH15, HEL114, MV, Mvinculin | 1.00 | infobox |
| Vinculin | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RKC, 1RKE, 1SYQ, 1TR2, 2GWW, 2IBF, 3H2U, 3H2V, 3MYI, 3TJ5, 3TJ6, 3VF0, 4DJ9, 4EHP, 1YDI, 2HSQ, 3RF3, 3S90,… | 1.00 | infobox |
| Vinculin | Band | 10q22.2 | 1.00 | infobox |
| Vinculin | Band | 14 A3|14 11.53 cM | 1.00 | infobox |
| Vinculin | Bgee | saphenous vein | 1.00 | infobox |
| Vinculin | Bgee | urethra | 1.00 | infobox |
| Vinculin | Bgee | vena cava | 1.00 | infobox |
| Vinculin | Bgee | smooth muscle tissue | 1.00 | infobox |
| Vinculin | Bgee | right coronary artery | 1.00 | infobox |
| Vinculin | Bgee | popliteal artery | 1.00 | infobox |
| Vinculin | Bgee | tibial arteries | 1.00 | infobox |
| Vinculin | Bgee | nipple | 1.00 | infobox |
| Vinculin | Bgee | seminal vesicula | 1.00 | infobox |
| Vinculin | Bgee | Descending thoracic aorta | 1.00 | infobox |
| Vinculin | Bgee | tunica media of zone of aorta | 1.00 | infobox |
| Vinculin | Bgee | calvaria | 1.00 | infobox |
| Vinculin | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Vinculin | Bgee | tibiofemoral joint | 1.00 | infobox |
| Vinculin | Bgee | umbilical cord | 1.00 | infobox |
| Vinculin | Bgee | ascending aorta | 1.00 | infobox |
| Vinculin | Bgee | right lung | 1.00 | infobox |
| Vinculin | Bgee | left lung | 1.00 | infobox |
| Vinculin | Bgee | carotid body | 1.00 | infobox |
| Vinculin | Bgee | left lung lobe | 1.00 | infobox |
| Vinculin | BioGPS | More reference expression data | 1.00 | infobox |
| Vinculin | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Vinculin | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| Vinculin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Vinculin | End | 74,121,363 bp | 1.00 | infobox |
| Vinculin | End | 21,083,744 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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