Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

APPL2: Overview, Related Topics & Entities

DCC-interacting protein 13-beta is a protein that in humans is encoded by the APPL2 gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

APPL2 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around APPL2.

Related topics
2
Source areas
1
Connected nodes
3
Extracted relationships
114
Concept neighborhoods
4
Bridge connections
3

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
APPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H8S, 5C5B
Band
12q23.3 · 10|10 C1
Bgee
skin of leg · skin of abdomen · rectum · mucosa of transverse colon · ventricular zone
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How APPL2 connects Entity context

The extracted context around APPL2 shows recurring relationship patterns in the source. For example, APPL2 → adiponectin-activated signaling pathway, cell cycle, cell population proliferation, cell projection, cellular response to hepatocyte growth factor stimulus, cold acclimation, cytoplasm, cytoplasmic vesicle, diet induced thermogenesis, early endosome membrane, early phagosome, early phagosome membrane, endosome, endosome membrane, extracellular exosome, glucose homeostasis, macropinosome, membrane, negative regulation of cellular response to insulin stimulus, negative regulation of cytokine production involved in inflammatory response Another extracted example is APPL2 → Achilles tendon, bronchial epithelial cell, canal of the cervix, cerebellar cortex, cerebellar vermis, ciliary body, ectocervix, epithelium of stomach, iris, lacrimal gland, lobe of cerebellum, mucosa of transverse colon, neural layer of retina, parotid gland, rectum, retinal pigment epithelium, skin of abdomen, skin of leg, stromal cell of endometrium, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

APPL2

Top relations

Gene ontology · 49
APPL2 → adiponectin-activated signaling pathway, cell cycle, cell population proliferation, cell projection, cellular response to hepatocyte growth factor stimulus, cold acclimation, cytoplasm, cytoplasmic vesicle, diet induced thermogenesis, early endosome membrane, early phagosome, early phagosome membrane, endosome, endosome membrane, extracellular exosome, glucose homeostasis, macropinosome, membrane, negative regulation of cellular response to insulin stimulus, negative regulation of cytokine production involved in inflammatory response
Bgee · 20
APPL2 → Achilles tendon, bronchial epithelial cell, canal of the cervix, cerebellar cortex, cerebellar vermis, ciliary body, ectocervix, epithelium of stomach, iris, lacrimal gland, lobe of cerebellum, mucosa of transverse colon, neural layer of retina, parotid gland, rectum, retinal pigment epithelium, skin of abdomen, skin of leg, stromal cell of endometrium, ventricular zone
RNA expression pattern · 20
APPL2 → Achilles tendon, bronchial epithelial cell, canal of the cervix, cerebellar cortex, cerebellar vermis, ciliary body, ectocervix, epithelium of stomach, iris, lacrimal gland, lobe of cerebellum, mucosa of transverse colon, neural layer of retina, parotid gland, rectum, retinal pigment epithelium, skin of abdomen, skin of leg, stromal cell of endometrium, ventricular zone
Band · 2
APPL2 → 10|10 C1, 12q23.3
Chr. · 2
APPL2 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
APPL2 → 105,236,203 bp, 83,484,602 bp
related to External links · 2
APPL2 → Human APPL2, UCSC Genome Browser
Aliases · 1
APPL2 → APPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
Available structures · 1
APPL2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H8S, 5C5B
BioGPS · 1
APPL2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human gene chr band chromosome 12 location protein mouse external search 236 203 end 105 10 484 602 ucsc

APPL2 relationships Subject–Predicate–Object triples

TTTA extracted 114 structured relationships around APPL2. Examples in this analysis include APPL2 → Aliases → APPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 and APPL2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H8S, 5C5B. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
APPL2AliasesAPPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 21.00infobox
APPL2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H8S, 5C5B1.00infobox
APPL2Band12q23.31.00infobox
APPL2Band10|10 C11.00infobox
APPL2Bgeeskin of leg1.00infobox
APPL2Bgeeskin of abdomen1.00infobox
APPL2Bgeerectum1.00infobox
APPL2Bgeemucosa of transverse colon1.00infobox
APPL2Bgeeventricular zone1.00infobox
APPL2BgeeAchilles tendon1.00infobox
APPL2Bgeestromal cell of endometrium1.00infobox
APPL2Bgeecanal of the cervix1.00infobox
APPL2Bgeeectocervix1.00infobox
APPL2Bgeebronchial epithelial cell1.00infobox
APPL2Bgeeretinal pigment epithelium1.00infobox
APPL2Bgeeciliary body1.00infobox
APPL2Bgeeiris1.00infobox
APPL2Bgeecerebellar cortex1.00infobox
APPL2Bgeeneural layer of retina1.00infobox
APPL2Bgeeparotid gland1.00infobox
APPL2Bgeelobe of cerebellum1.00infobox
APPL2Bgeecerebellar vermis1.00infobox
APPL2Bgeelacrimal gland1.00infobox
APPL2Bgeeepithelium of stomach1.00infobox
APPL2BioGPSMore reference expression data1.00infobox
APPL2Chr.Chromosome 12 (human)1.00infobox
APPL2Chr.Chromosome 10 (mouse)1.00infobox
APPL2DatabasesNCBI: entry; OMA: entry1.00infobox
APPL2End105,236,203 bp1.00infobox
APPL2End83,484,602 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around APPL2 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • APPL2
    • Protein
    • Gene
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Dcc-interacting
    • Encoded
    • External
    • Humans
  • appl2
    • Protein
    • Gene
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Dcc-interacting
    • Encoded
    • External
    • Humans
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Mouse
    • Search
    • Band
    • External
    • Humans
  • protein
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Reading
    • References
    • Ucsc
    • End
    • Mouse
    • Band

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the APPL2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

APPL2

Nodes4
Edges3
Triples114
Avg. degree1.5
Density0.5
Components1

Source & methodology

TTTA analyzes the structure around APPL2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — APPL2 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.