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ARHGAP25

Rho GTPase activating protein 25 is a protein that in humans is encoded by the ARHGAP25 gene. The gene is also known as KAIA0053. ARHGAP25 belongs to a family of Rho GTPase-modulating proteins that are implicated in actin remodeling, cell polarity, and cell migration.

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Aliases
ARHGAP25, HEL-S-308, KAIA0053, Rho GTPase activating protein 25
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V89
Band
2p13.3 · 6|6 D1
Bgee
granulocyte · blood · spleen · lymph node · monocyte
BioGPS
n/a
Chr.
Chromosome 2 (human) · Chromosome 6 (mouse)

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Map overview Semantic statistics

ARHGAP25

Nodes8
Edges7
Triples66
Avg. degree1.75
Density0.25
Components1

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ARHGAP25

Top relations

Bgee · 17
ARHGAP25 → appendix, blood, bone marrow, bone marrow cell, epithelium of colon, granulocyte, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, middle ear, monocyte, periodontal fiber, spleen, stroma of bone marrow, subcutaneous adipose tissue, thymus, tonsil
RNA expression pattern · 17
ARHGAP25 → appendix, blood, bone marrow, bone marrow cell, epithelium of colon, granulocyte, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, middle ear, monocyte, periodontal fiber, spleen, stroma of bone marrow, subcutaneous adipose tissue, thymus, tonsil
Gene ontology · 9
ARHGAP25 → actin filament organization, cytosol, GTPase activator activity, negative regulation of small GTPase mediated signal transduction, phagocytic cup, phagocytosis, engulfment, positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction
Band · 2
ARHGAP25 → 2p13.3, 6|6 D1
Chr. · 2
ARHGAP25 → Chromosome 2 (human), Chromosome 6 (mouse)
End · 2
ARHGAP25 → 68,826,833 bp, 87,510,241 bp
Aliases · 1
ARHGAP25 → ARHGAP25, HEL-S-308, KAIA0053, Rho GTPase activating protein 25
Available structures · 1
ARHGAP25 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V89
BioGPS · 1
ARHGAP25 → n/a
Databases · 1
ARHGAP25 → NCBI: entry; OMA: entry

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Important terminology

gene bp chr human band chromosome rho protein gtpase location actin mouse activating 25 kaia0053 cell search 826 833 end

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ARHGAP25AliasesARHGAP25, HEL-S-308, KAIA0053, Rho GTPase activating protein 251.00infobox
ARHGAP25Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V891.00infobox
ARHGAP25Band2p13.31.00infobox
ARHGAP25Band6|6 D11.00infobox
ARHGAP25Bgeegranulocyte1.00infobox
ARHGAP25Bgeeblood1.00infobox
ARHGAP25Bgeespleen1.00infobox
ARHGAP25Bgeelymph node1.00infobox
ARHGAP25Bgeemonocyte1.00infobox
ARHGAP25Bgeebone marrow cell1.00infobox
ARHGAP25Bgeeappendix1.00infobox
ARHGAP25Bgeeperiodontal fiber1.00infobox
ARHGAP25Bgeetonsil1.00infobox
ARHGAP25Bgeeepithelium of colon1.00infobox
ARHGAP25Bgeemesenteric lymph nodes1.00infobox
ARHGAP25Bgeethymus1.00infobox
ARHGAP25Bgeebone marrow1.00infobox
ARHGAP25Bgeelumbar spinal ganglion1.00infobox
ARHGAP25Bgeestroma of bone marrow1.00infobox
ARHGAP25Bgeesubcutaneous adipose tissue1.00infobox
ARHGAP25Bgeemiddle ear1.00infobox
ARHGAP25BioGPSn/a1.00infobox
ARHGAP25Chr.Chromosome 2 (human)1.00infobox
ARHGAP25Chr.Chromosome 6 (mouse)1.00infobox
ARHGAP25DatabasesNCBI: entry; OMA: entry1.00infobox
ARHGAP25End68,826,833 bp1.00infobox
ARHGAP25End87,510,241 bp1.00infobox
ARHGAP25EnsemblENSG000001632191.00infobox
ARHGAP25Entrez99381.00infobox
ARHGAP25External IDsOMIM: 610587; MGI: 2443687; GeneCards: ARHGAP251.00infobox

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