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Opiate

An opiate is an alkaloid substance derived from opium (or poppy straw). It differs from the similar term opioid in that the latter is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonists). Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum.…

Applications, Pharmacokinetics & Complications and side effects

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Overview

Synthesis

Pharmacokinetics

Indication

Complications and side effects

Pharmacology in pain

Absolute contraindications

Risk factors for prescription abuse

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Map overview Semantic statistics

Opiate

Nodes93
Edges92
Triples52
Avg. degree1.98
Density0.021505
Components1

How this topic connects Entity context

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Opiate

Top relations

related to overview · 8
Opiate → Alkaloids, Dihydrocodeine, It, Opiates, Papaverine, Possibly, The, Very
related to Indication · 6
Opiate → Another, COPD, GI, Given, In, Opiates
related to Synthesis · 6
Opiate → Gates, In, Once, Papaver, Therefore, While
has effect · 5
Opiate → Common, Of, There, This, While
related to Codeine · 5
Opiate → Codeine, Conversely, CYP2D6, Individuals, It
related to Meperidine · 4
Opiate → CNS, It, Meperidine, Normeperidine
related to Hydromorphone · 3
Opiate → H3G, Hydromorphone, It
related to Risk factors for prescription abuse · 2
Opiate → Past, The
is a · 1
Opiate → alkaloid substance derived from opium

Important terminology Word statistics

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Important terminology

morphine opioid use codeine effects opiates opioids opium used pain abuse may drug also patients receptors side hydromorphone doses high

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Opiateis aalkaloid substance derived from opium0.90text
sedationinstance ofindividuals with rapid or ultra-rapid CYP2D6 activity may metabolize the drug too quickly and experience dose-related side effects0.80text
fatal respiratory depression.FentanylFentanyl is a synthetic piperidine opioid structurally similar to arylpiperidinesinstance ofindividuals with rapid or ultra-rapid CYP2D6 activity may metabolize the drug too quickly and experience dose-related side effects0.80text
hyperalgesiainstance ofare associated with neurotoxic side effects0.80text
allodyniainstance ofare associated with neurotoxic side effects0.80text
myoclonus.OxymorphoneOxymorphone is a congener of morphineinstance ofare associated with neurotoxic side effects0.80text
fatal respiratory depressioninstance ofindividuals with rapid or ultra-rapid CYP2D6 activity may metabolize the drug too quickly and experience dose-related side effects0.80text
myoclonusinstance ofare associated with neurotoxic side effects0.80text
codeineinstance ofopioids0.80text
hydrocodoneinstance ofopioids0.80text
and hydromorphone have been traditionally used for treatment of acute viral coughinstance ofopioids0.80text
suicide.Iatrogenic physiologicalinstance ofmiddle-aged patients with substance use history and psychiatric comorbidities are seen with higher mortality risks0.80text

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