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Noscapine: History, Community, Culture & Applications

Noscapine, also known as narcotine, nectodon, nospen, anarcotine and (archaic) opiane, is a benzylisoquinoline alkaloid of the phthalideisoquinoline structural subgroup, which has been isolated from numerous species of the Papaveraceae (poppy) family. It lacks effects associated with opioids such as sedation, euphoria, or analgesia (pain-relief) and…

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Noscapine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Noscapine.

Related topics
104
Source areas
10
Connected nodes
114
Extracted relationships
144
Concept neighborhoods
23
Bridge connections
114

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Biosynthesis · 25 topics
Research · 21 topics
Side effects · 15 topics
Society and culture · 12 topics
Overview · 8 topics
Structure analysis · 8 topics
History · 5 topics
Interactions · 5 topics
Mechanism of action · 3 topics
Medical uses · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
R05DA07 (WHO)
Bioavailability
~30%
CAS Number
128-62-1 Y
ChEBI
CHEBI:73237 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Interactions

Biosynthesis

Mechanism of action

Structure analysis

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Noscapine connects Entity context

The extracted context around Noscapine shows recurring relationship patterns in the source. For example, Noscapine → An N-methylation, Another, AT1, BBE, C1, C2-C3, C4, C8, Canadine, CAS, Chorismic, CNMT, CoA, CXE1, CYP82X1, CYP82X2, CYP82Y1, DOPA, FAD, Finally Another extracted example is Noscapine → Again, CXCL10, Furthermore, IFN-c, IL-1β, IL-6, In, Khakpour, Moreover, NO, Shiri, The, They, TLR, TNF-α, Various, Zughaier. Use these groups to spot repeated connection types before inspecting the individual relationships.

Noscapine

Top relations

related to Biosynthesis · 53
Noscapine → An N-methylation, Another, AT1, BBE, C1, C2-C3, C4, C8, Canadine, CAS, Chorismic, CNMT, CoA, CXE1, CYP82X1, CYP82X2, CYP82Y1, DOPA, FAD, Finally
has effect · 17
Noscapine → Again, CXCL10, Furthermore, IFN-c, IL-1β, IL-6, In, Khakpour, Moreover, NO, Shiri, The, They, TLR, TNF-α, Various, Zughaier
related to history · 8
Noscapine → Finally, French, He, In, Jean-François Derosne, Narcotine, Paris, Pierre-Jean Robiquet
related to Noscapine in heroin · 8
Noscapine → Belgium, Detection, In, LCMS, Liège, Other, Since, This
related to Structure analysis · 6
Noscapine → C1, C3, HCl, In, The, When
related to Anticancer derivatives · 4
Noscapine → Analogs, N-alkyl, Similarly, Their
related to Noscapine biosynthesis reconstitution · 4
Noscapine → HN1, In, It, Many
related to Recreational use · 4
Noscapine → NMDA, The, There, Unlike
Legal status · 3
Noscapine → AU: S2 (Pharmacy medicine), EU: BE, SE: OTC, In general: ℞ (Prescription only)
related to Mechanism of action · 3
Noscapine → Evidence, Noscapine's, Pretreatment

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects also used anti-inflammatory narcotine antitussive use drugs heroin benzylisoquinoline alcohol inflammation pathway biosynthesis mechanism drug acid alkaloids form catalyzes

Noscapine relationships Subject–Predicate–Object triples

TTTA extracted 144 structured relationships around Noscapine. Examples in this analysis include Noscapine → 3D model (JSmol) → Interactive image and Noscapine → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Noscapine3D model (JSmol)Interactive image1.00infobox
NoscapineAHFS/Drugs.comInternational Drug Names1.00infobox
NoscapineATC codeR05DA07 (WHO)1.00infobox
NoscapineBioavailability~30%1.00infobox
NoscapineCAS Number128-62-1 Y1.00infobox
NoscapineChEBICHEBI:73237 N1.00infobox
NoscapineChEMBLChEMBL364713 Y1.00infobox
NoscapineChemSpider242139 Y1.00infobox
NoscapineCompTox Dashboard (EPA)DTXSID40233851.00infobox
NoscapineECHA InfoCard100.004.4551.00infobox
NoscapineElimination half-life1.5–4 h (mean 2.5 h)1.00infobox
NoscapineFormulaC22H23NO71.00infobox
NoscapineKEGGD01036 Y1.00infobox
NoscapineLegal statusAU: S2 (Pharmacy medicine)1.00infobox
NoscapineLegal statusEU: BE, SE: OTC1.00infobox
NoscapineLegal statusIn general: ℞ (Prescription only)1.00infobox
NoscapineMolar mass413.426 g·mol−11.00infobox
NoscapineOther namesNarcotine, nectodon, nospen, anarcotine1.00infobox
NoscapinePregnancy categoryContraindicated1.00infobox
NoscapinePubChem CID2751961.00infobox
NoscapineUNII8V32U4AOQU1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Noscapine bring nearby vocabulary together. In this analysis, examples include Effects, Anti-inflammatory and Pathway. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Noscapine
    • Effects
    • Anti-inflammatory
    • Pathway
    • Used
    • Drug
    • Inflammation
    • Biosynthetic
    • Derivatives
    • Found
    • Antitussive
    • Biosynthesis
    • Heroin
  • noscapine
    • Effects
    • Anti-inflammatory
    • Pathway
    • Used
    • Drug
    • Inflammation
    • Biosynthetic
    • Derivatives
    • Found
    • Antitussive
    • Biosynthesis
    • Heroin
  • anti-inflammatory
    • Effects
    • Nectodon
    • Nospen
    • Brominated
    • Derivatives
    • Found
    • Noscapine
    • Antitussive
    • Biosynthesis
    • Drug
    • Heroin
    • Inflammation
  • side effects
    • Anti-inflammatory
    • Noscapine
    • Alcohol
    • Drug
    • Used
    • Nectodon
    • Nospen
    • Brominated
    • Derivatives
    • Dextromethorphan
    • Found
    • Biosynthesis
  • biosynthesis
    • Nectodon
    • Nospen
    • Derivatives
    • Hemiacetal
    • Acid
    • Alkaloids
    • Drug
    • Heroin
    • Mechanism
    • Anti-inflammatory
    • Drugs
    • Narcotine
  • benzylisoquinoline alkaloids
    • Alkaloids
    • Benzylisoquinoline
    • Alkaloid
    • Nectodon
    • Nospen
    • Isolated
    • Tyrosine
    • Acid
    • Biosynthesis
    • Catalyzes
    • Drugs
    • Narcotine
  • antitussive
    • Effects
    • Used
    • Nectodon
    • Nospen
    • Derivatives
    • Biosynthesis
    • Drug
    • Heroin
    • Mechanism
    • Anti-inflammatory
    • Drugs
    • Narcotine
  • over-the-counter drugs
    • Use
    • Used
    • Nectodon
    • Nospen
    • Contaminants
    • Alkaloids
    • Drug
    • Heroin
    • Mechanism
    • Without
    • Narcotine
    • Noscapine

Connections between topic areas Semantic bridges

For Noscapine, one of the stronger structural bridges in this analysis connects Noscapine with Biosynthesis. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NoscapineBiosynthesis · splits 89 ⟂ 26
NoscapineResearch · splits 93 ⟂ 22
NoscapineSide effects · splits 99 ⟂ 16
NoscapineSociety and culture · splits 102 ⟂ 13
NoscapineOverview · splits 106 ⟂ 9
NoscapineStructure analysis · splits 106 ⟂ 9
NoscapineInteractions · splits 109 ⟂ 6
NoscapineHistory · splits 109 ⟂ 6
NoscapineMechanism of action · splits 111 ⟂ 4
NoscapineMedical uses · splits 112 ⟂ 3

Map overview Semantic statistics

Noscapine

Nodes115
Edges114
Triples144
Avg. degree1.98
Density0.017391
Components1

Source & methodology

TTTA analyzes the structure around Noscapine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Noscapine · EN edition · Analysis: TopicsToTalkAbout

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