Nuclear receptor 4A1

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Biochemistry

Monomer Homodimer Response element Heterodimerising COUP-TF

10 related topics

Evolution and homology

HUGO Nuclear receptor 4A2 Nuclear receptor 4A3 Conservation Immediate early genes

10 related topics

Interactions

Interact AKT1 Bcl-2 HIF1A Nuclear receptor co-repressor 2

8 related topics

Function

NF-κB H3K27ac Cytosporone B Dexamethasone Celastrol

6 related topics

Key facts & relationships

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Aliases: NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3, nuclear receptor subfamily 4 group A member 1, NH41
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QW4, 3V3E, 3V3Q, 4JGV, 4KZI, 4KZJ, 4KZM, 4RZE, 4RZF, 4RZG, 4RE8, 4REE, 4REF, 4WHF, 4WHG
Band: 12q13.13 · 15|15 F1
Bgee: gastric mucosa · left uterine tube · gallbladder · left ovary · tibial nerve
BioGPS: More reference expression data
Chr.: Chromosome 12 (human) · Chromosome 15 (mouse)

Topics to explore

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Overview

Protein
Gene
NR4A
Nuclear receptor
Intracellular
Transcription factors Transcription factor
Cell cycle
Inflammatory Inflammation
Apoptosis
Macrophages Macrophage
Phytohemagglutinin

Structure

Function

NF-κB
H3K27ac
Cytosporone B Cytosporone B?action=edit&redlink=1
Dexamethasone
Celastrol
Drug-induced gingival overgrowth Gingival enlargement

Biochemistry

Evolution and homology

HUGO Human Genome Organisation
Nuclear receptor 4A2
Nuclear receptor 4A3
Conservation Conserved sequence
Immediate early genes Immediate early gene
Intron
Homologous Homology (biology)
Rats Rat
Mice
Humans Human

Pathology

Metastasis

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

Nodes57

Edges56

Triples142

Avg. degree1.96

Density0.035088

Components1

How this topic connects Entity context

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Nuclear receptor 4A1

Top relations

Gene ontology · 36

Nuclear receptor 4A1 → cell migration involved in sprouting angiogenesis, cellular response to corticotropin-releasing hormone stimulus, cellular response to fibroblast growth factor stimulus, cellular response to vascular endothelial growth factor stimulus, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endothelial cell chemotaxis, fat cell differentiation, glucocorticoid receptor binding, intracellular receptor signaling pathway, metal ion binding, negative regulation of cell cycle, nuclear membrane, nuclear receptor activity, nucleoplasm, nucleus

Bgee · 19

Nuclear receptor 4A1 → adrenal gland, extensor digitorum longus muscle, gallbladder, gastric mucosa, granulocyte, left ovary, left uterine tube, medial head of gastrocnemius muscle, muscle of thigh, parotid gland, plantaris muscle, popliteal artery, right ovary, tibial arteries, tibial nerve, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava

RNA expression pattern · 19

related to Biochemistry · 13

Nuclear receptor 4A1 → COUP-TF, DNA, It, Moreover, NBRE, NR4A, NR4A1, Nuclear, Nur77, Nur77's, NurRE, RXR, The

related to Function · 13

Nuclear receptor 4A1 → Along, AP-1, Besides, H3K27ac, Mechanistically, NF-κB, No, NR4A, NR4A1, Nuclear, Overexpression, These, This

related to Evolution and homology · 11

Nuclear receptor 4A1 → DNA-binding, HUGO, It, N-terminal AB, NR4A, NR4A1, NR4A2, NR4A3, Nuclear, The, The C-terminal

related to Interactions · 8

Nuclear receptor 4A1 → AKT1, Bcl-2, HIF1A, Hippel, Lindau, Nuclear, Promyelocytic, Retinoid

Band · 2

Nuclear receptor 4A1 → 12q13.13, 15|15 F1

Chr. · 2

Nuclear receptor 4A1 → Chromosome 12 (human), Chromosome 15 (mouse)

End · 2

Nuclear receptor 4A1 → 101,172,676 bp, 52,059,507 bp

Important terminology Word statistics

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Important terminology

nr4a1 nuclear receptor 4a1 protein gene human bp nr4a transcription family chr band function members 12 response cell member domain

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Nuclear receptor 4A1	Aliases	NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3, nuclear receptor subfamily 4 group A member 1, NH41	1.00	infobox
Nuclear receptor 4A1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QW4, 3V3E, 3V3Q, 4JGV, 4KZI, 4KZJ, 4KZM, 4RZE, 4RZF, 4RZG, 4RE8, 4REE, 4REF, 4WHF, 4WHG	1.00	infobox
Nuclear receptor 4A1	Band	12q13.13	1.00	infobox
Nuclear receptor 4A1	Band	15\|15 F1	1.00	infobox
Nuclear receptor 4A1	Bgee	gastric mucosa	1.00	infobox
Nuclear receptor 4A1	Bgee	left uterine tube	1.00	infobox
Nuclear receptor 4A1	Bgee	gallbladder	1.00	infobox
Nuclear receptor 4A1	Bgee	left ovary	1.00	infobox
Nuclear receptor 4A1	Bgee	tibial nerve	1.00	infobox
Nuclear receptor 4A1	Bgee	popliteal artery	1.00	infobox
Nuclear receptor 4A1	Bgee	tibial arteries	1.00	infobox
Nuclear receptor 4A1	Bgee	right ovary	1.00	infobox
Nuclear receptor 4A1	Bgee	muscle of thigh	1.00	infobox
Nuclear receptor 4A1	Bgee	vena cava	1.00	infobox
Nuclear receptor 4A1	Bgee	granulocyte	1.00	infobox
Nuclear receptor 4A1	Bgee	adrenal gland	1.00	infobox
Nuclear receptor 4A1	Bgee	plantaris muscle	1.00	infobox
Nuclear receptor 4A1	Bgee	triceps brachii muscle	1.00	infobox
Nuclear receptor 4A1	Bgee	vastus lateralis muscle	1.00	infobox
Nuclear receptor 4A1	Bgee	tibialis anterior muscle	1.00	infobox
Nuclear receptor 4A1	Bgee	extensor digitorum longus muscle	1.00	infobox
Nuclear receptor 4A1	Bgee	parotid gland	1.00	infobox
Nuclear receptor 4A1	Bgee	medial head of gastrocnemius muscle	1.00	infobox
Nuclear receptor 4A1	BioGPS	More reference expression data	1.00	infobox
Nuclear receptor 4A1	Chr.	Chromosome 12 (human)	1.00	infobox
Nuclear receptor 4A1	Chr.	Chromosome 15 (mouse)	1.00	infobox
Nuclear receptor 4A1	Databases	NCBI: entry; OMA: entry	1.00	infobox
Nuclear receptor 4A1	End	52,059,507 bp	1.00	infobox
Nuclear receptor 4A1	End	101,172,676 bp	1.00	infobox
Nuclear receptor 4A1	Ensembl	ENSG00000123358	1.00	infobox

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