NCK1

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around NCK1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Interactions

Interact ABL1 CBL DNM1 DAG1

28 related topics

Function

Cytoplasm Transducing signals Receptor tyrosine kinases RAS Unfolded protein response

5 related topics

Gene

SH3 SH2 domains Chromosome 3

3 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CI8, 2CI9, 2JS0, 2JS2, 2JW4
Band: 3q22.3 · 9|9 E3.3
Bgee: human penis · Achilles tendon · oral cavity · epithelium of nasopharynx · decidua
BioGPS: More reference expression data
Chr.: Chromosome 3 (human) · Chromosome 9 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Gene

SH3 SH3 domain
SH2 domains SH2 domain
Chromosome 3

Function

Cytoplasm
Transducing signals Signal transduction
Receptor tyrosine kinases Receptor tyrosine kinase
RAS Ras superfamily
Unfolded protein response

Interactions

Interact Protein–protein interaction
ABL1 Abl gene
CBL CBL (gene)
DNM1
DAG1 Dystroglycan
EIF2B2
EPHB1 EPH receptor B1
EGFR Epidermal growth factor receptor
KHDRBS1
LCP2 Lymphocyte cytosolic protein 2
MAP4K1
MAP4K4
MINK1
NCKIPSD
NEDD9
PAK1
PDGFRB
PKN2
PTK2
RASA1
RICS RICS (gene)
RRAS
SOCS7
SOS1
TBK1 TANK-binding kinase 1
WASL WASL (gene)
WIPF1
WAS Wiskott-Aldrich syndrome protein

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes43

Edges42

Triples164

Avg. degree1.95

Density0.046512

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

NCK1

Top relations

Gene ontology · 50

NCK1 → actin filament organization, cadherin binding, cell migration, cell-cell junction, cytoplasm, cytoskeletal anchor activity, cytosol, endoplasmic reticulum, ephrin receptor binding, ephrin receptor signaling pathway, eukaryotic initiation factor eIF2 binding, Fc-gamma receptor signaling pathway involved in phagocytosis, lamellipodium assembly, molecular adaptor activity, negative regulation of cell death, negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation, negative regulation of insulin receptor signaling pathway, negative regulation of peptidyl-serine phosphorylation, negative regulation of PERK-mediated unfolded protein response, negative regulation of protein kinase activity

related to Interactions · 26

NCK1 → ABL1, CBL, DAG1, DNM1, EGFR, EIF2B2, EPHB1, KHDRBS1, LCP2, MAP4K1, MAP4K4, MINK1, NCKIPSD, NEDD9, PAK1, PDGFRB, PKN2, PTK2, RASA1, RICS

Bgee · 20

NCK1 → Achilles tendon, atrioventricular valve, decidua, epithelium of nasopharynx, esophagus, granulocyte, gums, human penis, intercostal muscle, masseter muscle, muscle of thigh, oral cavity, palpebral conjunctiva, saccule, skin of thigh, spermatocyte, tail of embryo, tonsil, uterus, vagina

RNA expression pattern · 20

related to Function · 14

NCK1 → ER, IRE1alpha, IRS-1, It, JNK, PKB, RAS, SH2, SH3, Src, The, These, This, UPR

related to External links · 6

NCK1 → Cell Migration Gateway Archived, December, July, Nck1 Archived, Wayback Machine, Wayback Machine Info

Band · 2

NCK1 → 3q22.3, 9|9 E3.3

Chr. · 2

NCK1 → Chromosome 3 (human), Chromosome 9 (mouse)

End · 2

NCK1 → 100,428,187 bp, 136,951,606 bp

Aliases · 1

NCK1 → NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene human bp pathway stress chr band within chromosome signaling involved adaptor expression tyrosine cell also mouse nck receptor

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
NCK1	Aliases	NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1	1.00	infobox
NCK1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CI8, 2CI9, 2JS0, 2JS2, 2JW4	1.00	infobox
NCK1	Band	3q22.3	1.00	infobox
NCK1	Band	9\|9 E3.3	1.00	infobox
NCK1	Bgee	human penis	1.00	infobox
NCK1	Bgee	Achilles tendon	1.00	infobox
NCK1	Bgee	oral cavity	1.00	infobox
NCK1	Bgee	epithelium of nasopharynx	1.00	infobox
NCK1	Bgee	decidua	1.00	infobox
NCK1	Bgee	palpebral conjunctiva	1.00	infobox
NCK1	Bgee	tonsil	1.00	infobox
NCK1	Bgee	vagina	1.00	infobox
NCK1	Bgee	gums	1.00	infobox
NCK1	Bgee	skin of thigh	1.00	infobox
NCK1	Bgee	granulocyte	1.00	infobox
NCK1	Bgee	atrioventricular valve	1.00	infobox
NCK1	Bgee	tail of embryo	1.00	infobox
NCK1	Bgee	esophagus	1.00	infobox
NCK1	Bgee	spermatocyte	1.00	infobox
NCK1	Bgee	masseter muscle	1.00	infobox
NCK1	Bgee	intercostal muscle	1.00	infobox
NCK1	Bgee	uterus	1.00	infobox
NCK1	Bgee	saccule	1.00	infobox
NCK1	Bgee	muscle of thigh	1.00	infobox
NCK1	BioGPS	More reference expression data	1.00	infobox
NCK1	Chr.	Chromosome 3 (human)	1.00	infobox
NCK1	Chr.	Chromosome 9 (mouse)	1.00	infobox
NCK1	Databases	NCBI: entry; OMA: entry	1.00	infobox
NCK1	End	136,951,606 bp	1.00	infobox
NCK1	End	100,428,187 bp	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3