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Myelin basic protein: Overview, Gene expression & Interactions

Myelin basic protein (MBP) is a protein important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintains the correct structure of myelin, interacting with the…

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Myelin basic protein topic overview

The analysis highlights Overview, Gene expression and Interactions as prominent areas in the source structure around Myelin basic protein.

Related topics
59
Source areas
5
Connected nodes
64
Extracted relationships
120
Related term clusters
24
Bridge connections
64

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 25 topics
Gene expression · 9 topics
Interactions · 9 topics
Role in disease · 8 topics
Structure · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MBP, myelin basic protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZGL, 1BX2, 1FV1, 1HQR, 1K2D, 1YMM
Band
18q23 · 18 E3|18 55.84 cM
Bgee
pons · external globus pallidus · inferior ganglion of vagus nerve · superior vestibular nucleus · C1 segment
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene expression

Structure

Role in disease

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Myelin basic protein connects Entity context

The extracted context around Myelin basic protein shows recurring relationship patterns in the source. For example, Myelin basic protein → axon ensheathment, calmodulin binding, cell periphery, cell projection, cell surface, central nervous system development, chemical synaptic transmission, compact myelin, hearing, immune response, internode region of axon, intracellular anatomical structure, maintenance of blood-brain barrier, MAPK cascade, membrane, membrane organization, myelin sheath, myelination, negative regulation of heterotypic cell-cell adhesion, nucleus Another extracted example is Myelin basic protein → C1 segment, deep cerebellar nuclei, dorsal motor nucleus of vagus nerve, dorsal tegmental nucleus, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lateral hypothalamus, medial geniculate nucleus, medial vestibular nucleus, optic nerve, pars reticulata, pons, pontine nuclei, substantia nigra, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.

Myelin basic protein

Top relations

Gene ontology · 29
Myelin basic protein → axon ensheathment, calmodulin binding, cell periphery, cell projection, cell surface, central nervous system development, chemical synaptic transmission, compact myelin, hearing, immune response, internode region of axon, intracellular anatomical structure, maintenance of blood-brain barrier, MAPK cascade, membrane, membrane organization, myelin sheath, myelination, negative regulation of heterotypic cell-cell adhesion, nucleus
Bgee · 20
Myelin basic protein → C1 segment, deep cerebellar nuclei, dorsal motor nucleus of vagus nerve, dorsal tegmental nucleus, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lateral hypothalamus, medial geniculate nucleus, medial vestibular nucleus, optic nerve, pars reticulata, pons, pontine nuclei, substantia nigra, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area
RNA expression pattern · 20
Myelin basic protein → C1 segment, deep cerebellar nuclei, dorsal motor nucleus of vagus nerve, dorsal tegmental nucleus, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lateral hypothalamus, medial geniculate nucleus, medial vestibular nucleus, optic nerve, pars reticulata, pons, pontine nuclei, substantia nigra, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area
related to Structure · 17
Myelin basic protein → ADP-ribosylation, Alternations, C1, C1-C6, C8, Cys-specific, IDP, IDPs, Like, Marburg's, MBP, MS, Myelin, N-terminal, NMR, Notably, Since
related to Gene expression · 10
Myelin basic protein → Alternative, CNS, Golli, Golli-MBP, MBP, MBP-related, MITF, N-terminal Golli, Schwann, The Golli
Band · 2
Myelin basic protein → 18 E3|18 55.84 cM, 18q23
Chr. · 2
Myelin basic protein → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
Myelin basic protein → 77,133,683 bp, 82,603,762 bp
Aliases · 1
Myelin basic protein → MBP, myelin basic protein
Available structures · 1
Myelin basic protein → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZGL, 1BX2, 1FV1, 1HQR, 1K2D, 1YMM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mbp myelin protein gene human system 18 basic structure bp nervous cells chromosome membrane immune chr band myelination citrullination mice

Myelin basic protein relationships Subject–Predicate–Object triples

TTTA extracted 120 structured relationships around Myelin basic protein. Examples in this analysis include Myelin basic protein → Aliases → MBP, myelin basic protein and Myelin basic protein → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZGL, 1BX2, 1FV1, 1HQR, 1K2D, 1YMM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Myelin basic proteinAliasesMBP, myelin basic protein1.00infobox
Myelin basic proteinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZGL, 1BX2, 1FV1, 1HQR, 1K2D, 1YMM1.00infobox
Myelin basic proteinBand18q231.00infobox
Myelin basic proteinBand18 E3|18 55.84 cM1.00infobox
Myelin basic proteinBgeepons1.00infobox
Myelin basic proteinBgeeexternal globus pallidus1.00infobox
Myelin basic proteinBgeeinferior ganglion of vagus nerve1.00infobox
Myelin basic proteinBgeesuperior vestibular nucleus1.00infobox
Myelin basic proteinBgeeC1 segment1.00infobox
Myelin basic proteinBgeesubthalamic nucleus1.00infobox
Myelin basic proteinBgeepars reticulata1.00infobox
Myelin basic proteinBgeeoptic nerve1.00infobox
Myelin basic proteinBgeeinferior olivary nucleus1.00infobox
Myelin basic proteinBgeedorsal motor nucleus of vagus nerve1.00infobox
Myelin basic proteinBgeeglobus pallidus1.00infobox
Myelin basic proteinBgeelateral geniculate nucleus1.00infobox
Myelin basic proteinBgeemedial geniculate nucleus1.00infobox
Myelin basic proteinBgeedeep cerebellar nuclei1.00infobox
Myelin basic proteinBgeedorsal tegmental nucleus1.00infobox
Myelin basic proteinBgeepontine nuclei1.00infobox
Myelin basic proteinBgeelateral hypothalamus1.00infobox
Myelin basic proteinBgeemedial vestibular nucleus1.00infobox
Myelin basic proteinBgeeventral tegmental area1.00infobox
Myelin basic proteinBgeesubstantia nigra1.00infobox
Myelin basic proteinBioGPSMore reference expression data1.00infobox
Myelin basic proteinChr.Chromosome 18 (human)1.00infobox
Myelin basic proteinChr.Chromosome 18 (mouse)1.00infobox
Myelin basic proteinDatabasesNCBI: entry; OMA: entry1.00infobox
Myelin basic proteinEnd77,133,683 bp1.00infobox
Myelin basic proteinEnd82,603,762 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Myelin basic protein bring nearby vocabulary together. In this analysis, examples include Myelin, Protein and System. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Myelin basic protein
    • Myelin
    • Protein
    • System
    • Structure
    • Nervous
    • Membrane
    • External
    • Sheath
    • Expression
    • Location
    • Myelination
    • Mbp
  • myelin basic protein
    • Myelin
    • Protein
    • System
    • Structure
    • Nervous
    • Membrane
    • Chromosome
    • Proteins
    • Human
    • External
    • Sheath
    • Expression
  • protein
    • System
    • Chromosome
    • Human
    • Structure
    • External
    • Gene
    • Cns
    • Expression
    • Location
    • Bp
    • Chr
    • Cells
  • nervous system
    • Nervous
    • System
    • Sheath
    • Myelin
    • Immune
    • Membrane
    • Myelination
    • Protein
    • External
    • Basic
    • Expression
    • Location
  • myelin sheath
    • Protein
    • External
    • System
    • Structure
    • Expression
    • Location
    • Nervous
    • Membrane
    • Band
    • Positive
    • Sheath
    • Bp
  • gene
    • Chromosome
    • Expression
    • Human
    • Location
    • Bp
    • Chr
    • Mbp
    • Structure
    • External
    • Band
    • Golli
    • Protein
  • chromosome 18
    • Human
    • Bp
    • Chr
    • Location
    • Band
    • External
    • Gene
    • Expression
    • Protein
    • Cells
    • Structure
    • Sheath
  • central nervous system
    • Nervous
    • System
    • Sheath
    • Myelin
    • Immune
    • Membrane
    • Myelination
    • Protein
    • External
    • Basic
    • Expression
    • Location

Connections between topic areas Semantic bridges

For Myelin basic protein, one of the stronger structural bridges in this analysis connects Myelin basic protein with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Myelin basic protein — Overview · splits 39 ⟂ 26
Myelin basic protein — Gene expression · splits 55 ⟂ 10
Myelin basic protein — Interactions · splits 55 ⟂ 10
Myelin basic protein — Structure · splits 56 ⟂ 9
Myelin basic protein — Role in disease · splits 56 ⟂ 9

Map overview Semantic statistics

Myelin basic protein

Nodes65
Edges64
Triples120
Avg. degree1.97
Density0.030769
Components1

Source & methodology

TTTA analyzes the structure around Myelin basic protein to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Gene expression & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Myelin basic protein · EN edition · Analysis: TopicsToTalkAbout

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