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Melatonin is a naturally occurring hormone produced in the brain that is also used as a dietary supplement and medication. As a hormone, melatonin is released by the pineal gland and is involved in sleep–wake cycles. As a supplement and medication, it is often used for the short-term treatment of disrupted sleep patterns such as from jet lag or shift…
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Melatonin as a medication and supplement | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Melatonin as a medication and supplement | Addiction liability | None | 1.00 | infobox |
| Melatonin as a medication and supplement | AHFS/Drugs.com | Consumer Drug Information | 1.00 | infobox |
| Melatonin as a medication and supplement | AHFS/Drugs.com | MedFacts Natural Products | 1.00 | infobox |
| Melatonin as a medication and supplement | ATC code | N05CH01 (WHO) | 1.00 | infobox |
| Melatonin as a medication and supplement | Bioavailability | ~15% (range 2.5–50%) | 1.00 | infobox |
| Melatonin as a medication and supplement | CAS Number | 73-31-4 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | ChEBI | CHEBI:16796 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | ChEMBL | ChEMBL45 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | ChemSpider | 872 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | Dependence liability | Physical: Low Psychological: None | 1.00 | infobox |
| Melatonin as a medication and supplement | Drug class | Melatonin receptor agonist | 1.00 | infobox |
| Melatonin as a medication and supplement | DrugBank | DB01065 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | Duration of action | A few hours | 1.00 | infobox |
| Melatonin as a medication and supplement | Elimination half-life | IR: 20–60 minutes PR: 3.5–4 hours | 1.00 | infobox |
| Melatonin as a medication and supplement | Excretion | Kidney | 1.00 | infobox |
| Melatonin as a medication and supplement | Formula | C13H16N2O2 | 1.00 | infobox |
| Melatonin as a medication and supplement | IUPHAR/BPS | 224 | 1.00 | infobox |
| Melatonin as a medication and supplement | KEGG | D08170 Y | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | CA: OTC / Rx-only | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | US: OTC | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | EU: Rx, OTC | 1.00 | infobox |
| Melatonin as a medication and supplement | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Melatonin as a medication and supplement | License data | US DailyMed: Melatonin | 1.00 | infobox |
| Melatonin as a medication and supplement | Melting point | 117 °C (243 °F) | 1.00 | infobox |
| Melatonin as a medication and supplement | Metabolism | Liver via CYP1A2 mediated 6-hydroxylation | 1.00 | infobox |
| Melatonin as a medication and supplement | Metabolites | 6-Hydroxymelatonin, N-acetyl-5-hydroxytryptamine, 5-methoxytryptamine | 1.00 | infobox |
| Melatonin as a medication and supplement | Molar mass | 232.283 g·mol−1 | 1.00 | infobox |
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