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Misoprostol

Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. It is taken by mouth when used to prevent gastric ulcers in people taking nonsteroidal anti-inflammatory drugs (NSAID). For abortions it is…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A02BB01 (WHO) G02AD06 (WHO)
Bioavailability
extensively absorbed
CAS Number
59122-46-2 Y
ChEMBL
ChEMBL606 Y

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Overview

Medical uses

Adverse effects

Pharmacology

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Misoprostol

Nodes83
Edges82
Triples107
Avg. degree1.98
Density0.024096
Components1

How this topic connects Entity context

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Misoprostol

Top relations

related to Black market · 17
Misoprostol → As, Dobbs, Failed, Following, Illegal, Jackson Women's Health Organization, Latin America, Low-income, Many, Mexico, New York City, Texas, The, United States, United States Supreme Court, US, Use
related to Latin America · 10
Misoprostol → Argentina, Brazil, Green Wave, In, In Cuba, It, Latin America, Mexico, Misoprostol's, Uruguay
related to Society and culture · 10
Misoprostol → Essential Medicines, Gynecologists, In, In August, It, LLC, Obstetricians, Searle, The American College, World Health Organization's List
has prevention · 8
Misoprostol → AMP, Arthrotec, G-protein, However, It, Misoprostol-induced, NSAID-induced, NSAIDs
Legal status · 6
Misoprostol → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances) Hospital use only, CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Abortion · 6
Misoprostol → It, Medical, Mifepristone, RU-486, The World Health Organization, WHO
related to Mechanism of action · 6
Misoprostol → E2, EP1, EP2, EP3, EP4, This
related to Postpartum bleeding · 4
Misoprostol → It, Orally, Oxytocin, Rectally
Pregnancy category · 2
Misoprostol → AU: X (High risk), Used for terminating pregnancy
has effect · 2
Misoprostol → In, The

Important terminology Word statistics

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Important terminology

abortion used use mifepristone labor ulcers abortions also women induction pregnancy uterine treatment gastric may medication bleeding cervix effective medical

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Misoprostol3D model (JSmol)Interactive image1.00infobox
MisoprostolAHFS/Drugs.comMonograph1.00infobox
MisoprostolATC codeA02BB01 (WHO) G02AD06 (WHO)1.00infobox
MisoprostolBioavailabilityextensively absorbed1.00infobox
MisoprostolCAS Number59122-46-2 Y1.00infobox
MisoprostolChEMBLChEMBL606 Y1.00infobox
MisoprostolChemSpider4445541 Y1.00infobox
MisoprostolCompTox Dashboard (EPA)DTXSID70208971.00infobox
MisoprostolDrugBankDB00929 Y1.00infobox
MisoprostolECHA InfoCard100.190.5211.00infobox
MisoprostolElimination half-life20–40 minutes1.00infobox
MisoprostolExcretionUrine (80%)1.00infobox
MisoprostolFormulaC22H38O51.00infobox
MisoprostolIUPHAR/BPS19361.00infobox
MisoprostolKEGGD00419 Y1.00infobox
MisoprostolLegal statusAU: S4 (Prescription only)1.00infobox
MisoprostolLegal statusBR: Class C1 (Other controlled substances) Hospital use only1.00infobox
MisoprostolLegal statusCA: ℞-only1.00infobox
MisoprostolLegal statusUK: POM (Prescription only)1.00infobox
MisoprostolLegal statusUS: ℞-only1.00infobox
MisoprostolLegal statusEU: Rx-only1.00infobox
MisoprostolLicense dataUS DailyMed: Misoprostol1.00infobox
MisoprostolMedlinePlusa6890091.00infobox
MisoprostolMetabolismLiver (extensive to misoprostic acid)1.00infobox
MisoprostolMolar mass382.541 g·mol−11.00infobox
MisoprostolPregnancy categoryAU: X (High risk)1.00infobox
MisoprostolPregnancy categoryUsed for terminating pregnancy1.00infobox
MisoprostolProtein binding80–90% (active metabolite, misoprostol acid)1.00infobox
MisoprostolPubChem CID52823811.00infobox
MisoprostolRoutes of administrationBy mouth, rectal, intravaginal, sublingual1.00infobox

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