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The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 α (IRE1α) is an enzyme that in humans is encoded by the ERN1 gene.
Specific roles in the brain, Signaling & Clinical significance
Explore the main themes, entities and connections around ERN1. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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ire1α gene kinase bp protein human chr band activity chromosome 17 enzyme ire1 endoplasmic rnase domain signaling unfolded response stress
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ERN1 | 2.7.11.1 | ↗ | 1.00 | infobox |
| ERN1 | Aliases | ERN1, IRE1, IRE1P, IRE1a, hIRE1p, endoplasmic reticulum to nucleus signaling 1 | 1.00 | infobox |
| ERN1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HZ6, 3P23, 4U6R, 4Z7G, 4Z7H, 4YZC, 4YZ9, 4YZD, 5HGI | 1.00 | infobox |
| ERN1 | Band | 17q23.3 | 1.00 | infobox |
| ERN1 | Band | 11|11 E1 | 1.00 | infobox |
| ERN1 | Bgee | parotid gland | 1.00 | infobox |
| ERN1 | Bgee | decidua | 1.00 | infobox |
| ERN1 | Bgee | amniotic fluid | 1.00 | infobox |
| ERN1 | Bgee | secondary oocyte | 1.00 | infobox |
| ERN1 | Bgee | right adrenal cortex | 1.00 | infobox |
| ERN1 | Bgee | seminal vesicula | 1.00 | infobox |
| ERN1 | Bgee | left adrenal cortex | 1.00 | infobox |
| ERN1 | Bgee | body of pancreas | 1.00 | infobox |
| ERN1 | Bgee | caput epididymis | 1.00 | infobox |
| ERN1 | Bgee | germinal epithelium | 1.00 | infobox |
| ERN1 | Bgee | primary oocyte | 1.00 | infobox |
| ERN1 | Bgee | gastrula | 1.00 | infobox |
| ERN1 | Bgee | lacrimal gland | 1.00 | infobox |
| ERN1 | Bgee | submandibular gland | 1.00 | infobox |
| ERN1 | Bgee | adrenal gland | 1.00 | infobox |
| ERN1 | Bgee | zygote | 1.00 | infobox |
| ERN1 | BioGPS | More reference expression data | 1.00 | infobox |
| ERN1 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| ERN1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| ERN1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ERN1 | End | 64,130,819 bp | 1.00 | infobox |
| ERN1 | End | 106,378,678 bp | 1.00 | infobox |
| ERN1 | Ensembl | ENSG00000178607 | 1.00 | infobox |
| ERN1 | Entrez | 2081 | 1.00 | infobox |
| ERN1 | Enzyme activity | Enzyme activityEC #BRENDAExPASyKEGGMetaCyc2.7.11.1↗↗↗↗ | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
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