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SATB2: Regions & Products

Special AT-rich sequence-binding protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is encoded by the SATB2 gene. SATB2 is a DNA-binding protein that specifically binds nuclear matrix attachment regions and is involved in transcriptional regulation and chromatin remodeling. SATB2 shows a restricted mode of expression…

Language: English [EN]
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SATB2 topic overview

The analysis highlights Regions and Products as prominent areas in the source structure around SATB2.

Related topics
18
Source areas
4
Connected nodes
22
Extracted relationships
107
Concept neighborhoods
13
Bridge connections
22

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics
Clinical significance · 5 topics
Function · 5 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SATB2, GLSS, SATB homeobox 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WI3, 1WIZ, 2CSF
Band
2q33.1 · 1|1 C1.3
Bgee
periodontal fiber · mucosa of sigmoid colon · tibia · rectum · mucosa of ileum
BioGPS
n/a
Chr.
Chromosome 2 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Structure

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SATB2 connects Entity context

The extracted context around SATB2 shows recurring relationship patterns in the source. For example, SATB2 → cartilage development, cellular response to organic substance, chromatin binding, chromatin organization, chromatin remodeling, commitment of neuronal cell to specific neuron type in forebrain, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic pattern specification, embryonic skeletal system morphogenesis, histone deacetylase complex, multicellular organism development, negative regulation of transcription by RNA polymerase II, neuron migration, nuclear matrix, nucleoplasm, nucleus, osteoblast development, positive regulation of transcription by RNA polymerase II Another extracted example is SATB2 → barrel cortex, body of femur, Brodmann area 46, Dermatocranium, facial skeleton, left colon, mandible, maxilla, membranous bone, middle temporal gyrus, molar, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, periodontal fiber, postcentral gyrus, rectum, rib, superior frontal gyrus, tibia. Use these groups to spot repeated connection types before inspecting the individual relationships.

SATB2

Top relations

Gene ontology · 31
SATB2 → cartilage development, cellular response to organic substance, chromatin binding, chromatin organization, chromatin remodeling, commitment of neuronal cell to specific neuron type in forebrain, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic pattern specification, embryonic skeletal system morphogenesis, histone deacetylase complex, multicellular organism development, negative regulation of transcription by RNA polymerase II, neuron migration, nuclear matrix, nucleoplasm, nucleus, osteoblast development, positive regulation of transcription by RNA polymerase II
Bgee · 20
SATB2 → barrel cortex, body of femur, Brodmann area 46, Dermatocranium, facial skeleton, left colon, mandible, maxilla, membranous bone, middle temporal gyrus, molar, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, periodontal fiber, postcentral gyrus, rectum, rib, superior frontal gyrus, tibia
RNA expression pattern · 20
SATB2 → barrel cortex, body of femur, Brodmann area 46, Dermatocranium, facial skeleton, left colon, mandible, maxilla, membranous bone, middle temporal gyrus, molar, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, periodontal fiber, postcentral gyrus, rectum, rib, superior frontal gyrus, tibia
related to Structure · 6
SATB2 → A590T, CUT, I481V, I730T, The, There
Band · 2
SATB2 → 1|1 C1.3, 2q33.1
Chr. · 2
SATB2 → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
SATB2 → 199,471,266 bp, 57,017,809 bp
is a · 2
SATB2 → DNA-binding protein that specifically binds nuclear matrix attachment regions and is involved in transcriptional regulation and chromatin remodeling, protein that in humans is encoded by the SATB2 gene
related to External links · 2
SATB2 → Registry, UCSC Genome Browser
Aliases · 1
SATB2 → SATB2, GLSS, SATB homeobox 2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein human gene bp chr band chromosome mouse location dna-binding expressed oral cleft expression also nuclei specific development ucsc nuclear

SATB2 relationships Subject–Predicate–Object triples

TTTA extracted 107 structured relationships around SATB2. Examples in this analysis include SATB2 → Aliases → SATB2, GLSS, SATB homeobox 2 and SATB2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WI3, 1WIZ, 2CSF. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SATB2AliasesSATB2, GLSS, SATB homeobox 21.00infobox
SATB2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WI3, 1WIZ, 2CSF1.00infobox
SATB2Band2q33.11.00infobox
SATB2Band1|1 C1.31.00infobox
SATB2Bgeeperiodontal fiber1.00infobox
SATB2Bgeemucosa of sigmoid colon1.00infobox
SATB2Bgeetibia1.00infobox
SATB2Bgeerectum1.00infobox
SATB2Bgeemucosa of ileum1.00infobox
SATB2Bgeemucosa of transverse colon1.00infobox
SATB2Bgeemiddle temporal gyrus1.00infobox
SATB2BgeeBrodmann area 461.00infobox
SATB2Bgeesuperior frontal gyrus1.00infobox
SATB2Bgeepostcentral gyrus1.00infobox
SATB2Bgeefacial skeleton1.00infobox
SATB2BgeeDermatocranium1.00infobox
SATB2Bgeemembranous bone1.00infobox
SATB2Bgeemandible1.00infobox
SATB2Bgeemaxilla1.00infobox
SATB2Bgeerib1.00infobox
SATB2Bgeebody of femur1.00infobox
SATB2Bgeebarrel cortex1.00infobox
SATB2Bgeeleft colon1.00infobox
SATB2Bgeemolar1.00infobox
SATB2BioGPSn/a1.00infobox
SATB2Chr.Chromosome 2 (human)1.00infobox
SATB2Chr.Chromosome 1 (mouse)1.00infobox
SATB2DatabasesNCBI: entry; OMA: entry1.00infobox
SATB2End199,471,266 bp1.00infobox
SATB2End57,017,809 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SATB2 bring nearby vocabulary together. In this analysis, examples include Ucsc, Cleft and Apparently. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Dna-binding
    • Chromatin
    • Colon
    • Matrix
    • Nuclear
    • Rectum
    • Regulation
    • Remodeling
    • Expressed
    • Gene
    • Human
    • Satb2
  • gene
    • Human
    • Location
    • Ucsc
    • Satb2
    • Bp
    • Chr
    • Chromosome
    • Function
    • Protein
    • Band
    • Mouse
    • External
  • dna-binding protein
    • Chromatin
    • Matrix
    • Nuclear
    • Regulation
    • Remodeling
    • Dna-binding
    • Protein
    • Colon
    • Rectum
    • Cell
    • Expressed
    • Function
  • nuclear matrix
    • Chromatin
    • Matrix
    • Nuclear
    • Regulation
    • Remodeling
    • Cell
    • Colon
    • Function
    • Rectum
    • Protein
    • Clefts
    • Development
  • chromatin remodeling
    • Matrix
    • Nuclear
    • Regulation
    • Remodeling
    • Dna-binding
    • Cell
    • Colon
    • Function
    • Rectum
    • Protein
    • Clefts
    • Development
  • chromosome translocations
    • Bp
    • Band
    • Location
    • Human
    • Function
    • Gene
    • Mouse
    • External
    • Colon
    • Matrix
    • Nuclear
    • Rectum
  • transcriptional regulation
    • Chromatin
    • Remodeling
    • Cell
    • Colon
    • Function
    • Rectum
    • Clefts
    • Development
    • Expressed
    • Expression
    • Specific
    • Ucsc
  • function
    • Location
    • Bp
    • Chr
    • Chromosome
    • Matrix
    • Nuclear
    • Rectum
    • Regulation
    • Remodeling
    • Clefts
    • Development
    • Gene

Connections between topic areas Semantic bridges

For SATB2, one of the stronger structural bridges in this analysis connects SATB2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SATB2Overview · splits 16 ⟂ 7
SATB2Function · splits 17 ⟂ 6
SATB2Clinical significance · splits 17 ⟂ 6
SATB2Structure · splits 20 ⟂ 3

Map overview Semantic statistics

SATB2

Nodes23
Edges22
Triples107
Avg. degree1.91
Density0.086957
Components1

Source & methodology

TTTA analyzes the structure around SATB2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SATB2 · EN edition · Analysis: TopicsToTalkAbout

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