GPER

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GPER topic overview

The analysis highlights Ligands, Role in normal tissues and Discovery as prominent areas in the source structure around GPER.

Related topics: 99
Source areas: 5
Connected nodes: 104
Extracted relationships: 230
Concept neighborhoods: 23
Bridge connections: 104

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Ligands · 45 topics

Role in normal tissues · 33 topics

Discovery · 11 topics

Function · 7 topics

Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: GPER1, Gper1, 6330420K13Rik, CMKRL2, Ceprl, FEG-1, GPCR-Br, Gper, Gpr30, CEPR, DRY12, LERGU, LERGU2, LyGPR, mER, G protein-coupled estrogen receptor 1
Band: 7p22.3 · 5|5 G2
Bgee: body of stomach · middle frontal gyrus · fundus · frontal pole · paraflocculus of cerebellum
BioGPS: More reference expression data
Chr.: Chromosome 7 (human) · Chromosome 5 (mouse)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GPER connects Entity context

The extracted context around GPER shows recurring relationship patterns in the source. For example, GPER → adenylate cyclase-activating G protein-coupled receptor signaling pathway, apoptotic chromosome condensation, apoptotic process, axon, axon terminus, cell cycle, cell differentiation, cell junction, cell projection, cellular response to estradiol stimulus, cellular response to glucose stimulus, cellular response to mineralocorticoid stimulus, cellular response to peptide hormone stimulus, cellular response to tumor necrosis factor, chromatin binding, cytoplasm, cytoplasmic vesicle, cytoplasmic vesicle membrane, cytoskeleton, dendrite Another extracted example is GPER → apex of heart, body of stomach, condyle, epithelium of stomach, external carotid artery, fossa, frontal pole, fundus, hand, internal carotid artery, middle frontal gyrus, otolith organ, paraflocculus of cerebellum, right adrenal cortex, right lobe of liver, substantia nigra, tendon of biceps brachii, testicle, trigeminal ganglion, utricle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 102

GPER → adenylate cyclase-activating G protein-coupled receptor signaling pathway, apoptotic chromosome condensation, apoptotic process, axon, axon terminus, cell cycle, cell differentiation, cell junction, cell projection, cellular response to estradiol stimulus, cellular response to glucose stimulus, cellular response to mineralocorticoid stimulus, cellular response to peptide hormone stimulus, cellular response to tumor necrosis factor, chromatin binding, cytoplasm, cytoplasmic vesicle, cytoplasmic vesicle membrane, cytoskeleton, dendrite

Bgee · 20

GPER → apex of heart, body of stomach, condyle, epithelium of stomach, external carotid artery, fossa, frontal pole, fundus, hand, internal carotid artery, middle frontal gyrus, otolith organ, paraflocculus of cerebellum, right adrenal cortex, right lobe of liver, substantia nigra, tendon of biceps brachii, testicle, trigeminal ganglion, utricle

RNA expression pattern · 20

related to External links · 14

GPER → Basic, Clinical Pharmacology, Estrogen, International Union, Ion Channels, IUPHAR Database, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Receptor, Receptors, This, United States National Library

related to Agonists · 11

GPER → DDE, DDT, Diarylpropionitrile, DPN, EquolEstradiolEthynylestradiolFulvestrant, G-1GenisteinGPER-L1GPER-L2HydroxytyrosolKeponeLNS8801NiacinNicotinamideNonylphenolOleuropeinProtocatechuic, ICI-182780, Methoxyestradiol2, PCB-4-OHAfimoxifeneAldosteroneAtrazineBisphenol ADaidzeinDDT, PPT, QuercetinRaloxifeneResveratrolSTXTamoxifenTectoridin

related to Discovery · 9

GPER → Based, GPCR, GPR30, However, In, RNA, Since, The, These

related to Ligands · 7

GPER → Although, CCL18, G-1, G15, G36, GPER-selective, Niacin

related to Reproductive tissue · 7

GPER → ERα, ERβ, Estradiol, GnRH, However, HPG, This

related to Central nervous system activity · 6

GPER → Contrarily, ERα, ERβ, Estradiol, It, There

related to Role in cancer · 6

GPER → Additionally, Although GPER, Consistent, In, Leydig, Many

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

estradiol receptor protein estrogen effects activation bp gene cancer also human protein-coupled erβ hormone chr band expression breast system found

GPER relationships Subject–Predicate–Object triples

TTTA extracted 230 structured relationships around GPER. Examples in this analysis include GPER → Aliases → GPER1, Gper1, 6330420K13Rik, CMKRL2, Ceprl, FEG-1, GPCR-Br, Gper, Gpr30, CEPR, DRY12, LERGU, LERGU2, LyGPR, mER, G protein-coupled estrogen receptor 1 and GPER → Band → 7p22.3. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
GPER	Aliases	GPER1, Gper1, 6330420K13Rik, CMKRL2, Ceprl, FEG-1, GPCR-Br, Gper, Gpr30, CEPR, DRY12, LERGU, LERGU2, LyGPR, mER, G protein-coupled estrogen receptor 1	1.00	infobox
GPER	Band	7p22.3	1.00	infobox
GPER	Band	5\|5 G2	1.00	infobox
GPER	Bgee	body of stomach	1.00	infobox
GPER	Bgee	middle frontal gyrus	1.00	infobox
GPER	Bgee	fundus	1.00	infobox
GPER	Bgee	frontal pole	1.00	infobox
GPER	Bgee	paraflocculus of cerebellum	1.00	infobox
GPER	Bgee	tendon of biceps brachii	1.00	infobox
GPER	Bgee	right lobe of liver	1.00	infobox
GPER	Bgee	apex of heart	1.00	infobox
GPER	Bgee	testicle	1.00	infobox
GPER	Bgee	right adrenal cortex	1.00	infobox
GPER	Bgee	external carotid artery	1.00	infobox
GPER	Bgee	otolith organ	1.00	infobox
GPER	Bgee	utricle	1.00	infobox
GPER	Bgee	internal carotid artery	1.00	infobox
GPER	Bgee	condyle	1.00	infobox
GPER	Bgee	fossa	1.00	infobox
GPER	Bgee	trigeminal ganglion	1.00	infobox
GPER	Bgee	epithelium of stomach	1.00	infobox
GPER	Bgee	substantia nigra	1.00	infobox
GPER	Bgee	hand	1.00	infobox
GPER	BioGPS	More reference expression data	1.00	infobox
GPER	Chr.	Chromosome 7 (human)	1.00	infobox
GPER	Chr.	Chromosome 5 (mouse)	1.00	infobox
GPER	Databases	NCBI: entry; OMA: entry	1.00	infobox
GPER	End	1,093,815 bp	1.00	infobox
GPER	End	139,413,555 bp	1.00	infobox
GPER	Ensembl	ENSG00000164850	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GPER bring nearby vocabulary together. In this analysis, examples include Cancer, Activation and Estradiol. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

GPER
- Cancer
- Activation
- Estradiol
- Erβ
- Found
- Effects
- Also
- Receptor
- Hypothalamus
- Breast
- Expression
- System
gper
- Cancer
- Activation
- Estradiol
- Erβ
- Found
- Effects
- Also
- Receptor
- Hypothalamus
- Breast
- Expression
- System
protein
- Membrane
- Receptors
- Protein-coupled
- Estradiol
- Receptor
- Cells
- Nucleus
- Human
- Signaling
- Gene
- External
- Location
gene
- Location
- Chromosome
- Bp
- Chr
- Human
- External
- Protein-coupled
- Receptor
- Mouse
- Band
- Function
- Gpr30
estradiol
- Rapid
- Protein-coupled
- Effects
- Activation
- Protein
- Cells
- Gper
- Nucleus
- Receptor
- Responsible
- Found
- Expressed
estrogen receptors
- Protein-coupled
- Receptor
- Gpr30
- Protein
- Receptors
- Gene
- External
- Location
- Chromosome
- Function
- Membrane
- Bp
interior of cells
- Expressed
- Rapid
- Signaling
- Hormone
- Estradiol
- External
- Protein
- Location
- Mouse
- Band
- Chromosome
- Function
nuclear hormone receptor
- Tumor
- System
- Signaling
- Location
- Cancer
- Growth
- Membrane
- Responsible
- Tissue
- Activation
- Expression
- Human

Connections between topic areas Semantic bridges

For GPER, one of the stronger structural bridges in this analysis connects GPER with Ligands. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

GPER — Ligands · splits 59 ⟂ 46

GPER — Role in normal tissues · splits 71 ⟂ 34

GPER — Discovery · splits 93 ⟂ 12

GPER — Function · splits 97 ⟂ 8

GPER — Overview · splits 101 ⟂ 4

Map overview Semantic statistics

GPER

Nodes105

Edges104

Triples230

Avg. degree1.98

Density0.019048

Components1

Source & methodology

TTTA analyzes the structure around GPER to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Ligands, Role in normal tissues & Discovery, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GPER · EN edition · Analysis: TopicsToTalkAbout