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Nicotinamide: Applications & Research

Nicotinamide (INN, BAN UK) or niacinamide (USAN US) (IUPAC name: 3-pyridinecarboxoamide) is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used orally (swallowed by mouth) to prevent and treat pellagra (niacin deficiency). While nicotinic acid (niacin) may be used for this purpose, nicotinamide…

Language: English [EN]
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Nicotinamide topic overview

The analysis highlights Applications and Research as prominent areas in the source structure around Nicotinamide.

Related topics
84
Source areas
6
Connected nodes
90
Extracted relationships
69
Concept neighborhoods
30
Bridge connections
90

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Chemistry · 34 topics
Overview · 34 topics
Medical uses · 9 topics
Research · 4 topics
Compendial status · 2 topics
Side effects · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
A11HA01 (WHO)
Boiling point
334 °C (633 °F)
CAS Number
98-92-0 Y
ChEBI
CHEBI:17154

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Chemistry

Compendial status

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Nicotinamide connects Entity context

The extracted context around Nicotinamide shows recurring relationship patterns in the source. For example, Nicotinamide → ATP, However, If, In, In NAD, NAD, NADH, NADP, The, This, When Another extracted example is Nicotinamide → American Academy, Current, Exceeding, Niacin B3, Normal, NOT, Ophthalmology, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Nicotinamide

Top relations

related to Biochemistry · 11
Nicotinamide → ATP, However, If, In, In NAD, NAD, NADH, NADP, The, This, When
related to Eye health · 8
Nicotinamide → American Academy, Current, Exceeding, Niacin B3, Normal, NOT, Ophthalmology, The
related to Biological role · 6
Nicotinamide → B3, It, N-substituted, NAD, NADH, The NADPH/NADP
related to Chemistry · 6
Nicotinamide → As, Examples, It, N-oxide, Organic Syntheses, The
related to Industrial production · 6
Nicotinamide → According, Industrial Chemistry, J1, Rhodococcus, The, Ullmann's Encyclopedia
related to Acne · 3
Nicotinamide → Cutibacterium, It, The
related to Food sources · 3
Nicotinamide → B3, It, Many
has effect · 2
Nicotinamide → At, Normal
3D model (JSmol) · 1
Nicotinamide → Interactive image
AHFS/Drugs.com · 1
Nicotinamide → Consumer Drug Information

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

acid nicotinic liver skin niacin nad vitamin may used b3 doses amide health high research eye effects acne reactions form

Nicotinamide relationships Subject–Predicate–Object triples

TTTA extracted 69 structured relationships around Nicotinamide. Examples in this analysis include Nicotinamide → 3D model (JSmol) → Interactive image and Nicotinamide → AHFS/Drugs.com → Consumer Drug Information. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Nicotinamide3D model (JSmol)Interactive image1.00infobox
NicotinamideAHFS/Drugs.comConsumer Drug Information1.00infobox
NicotinamideATC codeA11HA01 (WHO)1.00infobox
NicotinamideBoiling point334 °C (633 °F)1.00infobox
NicotinamideCAS Number98-92-0 Y1.00infobox
NicotinamideChEBICHEBI:171541.00infobox
NicotinamideChEMBLChEMBL11401.00infobox
NicotinamideChemSpider9111.00infobox
NicotinamideCompTox Dashboard (EPA)DTXSID20209291.00infobox
NicotinamideDensity1.40 g/cm3 g/cm31.00infobox
NicotinamideDrugBankDB027011.00infobox
NicotinamideECHA InfoCard100.002.4671.00infobox
NicotinamideFormulaC6H6N2O1.00infobox
NicotinamideKEGGD000361.00infobox
NicotinamideLegal statusUS: OTC1.00infobox
NicotinamideLicense dataUS DailyMed: Niacinamide1.00infobox
NicotinamideMelting point129.5 °C (265.1 °F)1.00infobox
NicotinamideMolar mass122.127 g·mol−11.00infobox
NicotinamideOther namesNAM, 3-pyridinecarboxamide niacinamide (USAN US) nicotinic acid amide vitamin PP nicotinic amide vitamin B31.00infobox
NicotinamidePronunciation/ˌnaɪəˈsɪnəmaɪd/, /ˌnɪkəˈtɪnəmaɪd/1.00infobox
NicotinamidePubChem CID9361.00infobox
NicotinamideRoutes of administrationoral, topical1.00infobox
NicotinamideUNII25X51I8RD41.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Nicotinamide bring nearby vocabulary together. In this analysis, examples include Skin, Acid and B3. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Nicotinamide
    • Skin
    • Acid
    • B3
    • Niacin
    • Nicotinic
    • Nad
    • Found
    • Role
    • Treatment
    • Vitamin
    • Potential
    • Acne
  • nicotinamide
    • Skin
    • Acid
    • B3
    • Niacin
    • Nicotinic
    • Nad
    • Found
    • Role
    • Treatment
    • Vitamin
    • Potential
    • Acne
  • vitamin b3
    • B3
    • Vitamin
    • Usan
    • Niacin
    • Nicotinic
    • Acid
    • Deficiency
    • Side
    • Nicotinamide
    • Acne
    • Also
    • Effects
  • nicotinic acid
    • Nicotinic
    • Niacin
    • Amide
    • B3
    • Skin
    • Nicotinamide
    • Nad
    • Usan
    • Nicotinonitrile
    • Side
    • Acne
    • Also
  • vitamin b3 complex
    • B3
    • Vitamin
    • Usan
    • Niacin
    • Nicotinic
    • Acid
    • Deficiency
    • Side
    • Nicotinamide
    • Acne
    • Also
    • Effects
  • citric acid cycle
    • Nicotinic
    • Niacin
    • Amide
    • B3
    • Nicotinamide
    • Skin
    • Nad
    • Deficiency
    • Usan
    • Nicotinonitrile
    • Side
    • Acne
  • amino acid
    • Nicotinic
    • Niacin
    • Amide
    • B3
    • Nicotinamide
    • Skin
    • Nad
    • Deficiency
    • Usan
    • Nicotinonitrile
    • Side
    • Acne
  • water-soluble vitamin
    • B3
    • Usan
    • Deficiency
    • Side
    • Acne
    • Also
    • Effects
    • Eye
    • Found
    • Health
    • Role
    • Amide

Connections between topic areas Semantic bridges

For Nicotinamide, one of the stronger structural bridges in this analysis connects Nicotinamide with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Nicotinamide — Overview · splits 56 ⟂ 35
Nicotinamide — Chemistry · splits 56 ⟂ 35
Nicotinamide — Medical uses · splits 81 ⟂ 10
Nicotinamide — Research · splits 86 ⟂ 5
Nicotinamide — Compendial status · splits 88 ⟂ 3

Map overview Semantic statistics

Nicotinamide

Nodes91
Edges90
Triples69
Avg. degree1.98
Density0.021978
Components1

Source & methodology

TTTA analyzes the structure around Nicotinamide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Nicotinamide · EN edition · Analysis: TopicsToTalkAbout

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