CCL18

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CCL18 topic overview

The analysis highlights Receptor, Gene and protein structure and Involvement in disease as prominent areas in the source structure around CCL18.

Related topics: 41
Source areas: 6
Connected nodes: 64
Extracted relationships: 150
Concept neighborhoods: 21
Bridge connections: 64

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Receptor · 13 topics

Gene and protein structure · 8 topics

Overview · 7 topics

Involvement in disease · 6 topics

Effector functions · 4 topics

Chemotactic functions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CCL18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18, C-C motif chemokine ligand 18
Available structures: Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4MHE
Band: 17q12
Bgee: lymph node · upper lobe of left lung · appendix · rectum · right lung
BioGPS: n/a
Chr.: Chromosome 17 (human)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Effector functions

Involvement in disease

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CCL18 connects Entity context

The extracted context around CCL18 shows recurring relationship patterns in the source. For example, CCL18 → antimicrobial humoral immune response mediated by antimicrobial peptide, CCR chemokine receptor binding, cell communication, cell-cell signaling, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, cytokine activity, extracellular region, extracellular space, G protein-coupled receptor signaling pathway, immune response, inflammatory response, lymphocyte chemotaxis, monocyte chemotaxis, neutrophil chemotaxis, positive regulation of ERK1 and ERK2 cascade Another extracted example is CCL18 → B-cells, CCL1, CCL18's, CCL18-mediated, CCR8, CCR8's, CCR8-CCL18, CXCL12-dependent, Following, Further, Furthermore, G-protein, GPCR, GPCRs, GPR30, However, PITPNM3, PITPNM3-CCL8, Pyk2, Src. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 25

CCL18 → antimicrobial humoral immune response mediated by antimicrobial peptide, CCR chemokine receptor binding, cell communication, cell-cell signaling, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, cytokine activity, extracellular region, extracellular space, G protein-coupled receptor signaling pathway, immune response, inflammatory response, lymphocyte chemotaxis, monocyte chemotaxis, neutrophil chemotaxis, positive regulation of ERK1 and ERK2 cascade

related to Receptor · 24

CCL18 → B-cells, CCL1, CCL18's, CCL18-mediated, CCR8, CCR8's, CCR8-CCL18, CXCL12-dependent, Following, Further, Furthermore, G-protein, GPCR, GPCRs, GPR30, However, PITPNM3, PITPNM3-CCL8, Pyk2, Src

related to Sources · 12

CCL18 → B-cells, Finally, Furthermore, IFN-gamma, IL-10, IL-13, IL-4, Its, Neither T-cells, T-helper, The, These

Bgee · 10

CCL18 → appendix, duodenum, gallbladder, left coronary artery, lymph node, rectum, right coronary artery, right lung, spleen, upper lobe of left lung

RNA expression pattern · 10

CCL18 → appendix, duodenum, gallbladder, left coronary artery, lymph node, rectum, right coronary artery, right lung, spleen, upper lobe of left lung

related to Chemotactic functions · 10

CCL18 → B-cells, Chemokines, Dendritic Cells, FoxP3, IL-10, It, T-cells, T-helper, T-regulatory, The T-regulatory

related to Immune activation · 10

CCL18 → B-cells, Coupled, Finally, Furthermore, IL-13, IL-4, Perhaps, T-helper, Th2, The

related to Immunosuppression · 7

CCL18 → Furthermore, IL-10, In, M2, T-cell, T-cells, T-regulatory

related to Autoimmunity and hypersensitivity · 6

CCL18 → Allergic, Furthermore, However, In, T-cells, T-helper

related to Breast cancer · 5

CCL18 → Perhaps CCL18, PITPNM3, T-cells, T-regulatory, The

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells immune receptor t-helper gene expressed dendritic t-cells cytokine functions protein involved chemokine binding human also role system effects effector

CCL18 relationships Subject–Predicate–Object triples

TTTA extracted 150 structured relationships around CCL18. Examples in this analysis include CCL18 → Aliases → CCL18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18, C-C motif chemokine ligand 18 and CCL18 → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4MHE. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CCL18	Aliases	CCL18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18, C-C motif chemokine ligand 18	1.00	infobox
CCL18	Available structures	Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes4MHE	1.00	infobox
CCL18	Band	17q12	1.00	infobox
CCL18	Bgee	lymph node	1.00	infobox
CCL18	Bgee	upper lobe of left lung	1.00	infobox
CCL18	Bgee	appendix	1.00	infobox
CCL18	Bgee	rectum	1.00	infobox
CCL18	Bgee	right lung	1.00	infobox
CCL18	Bgee	duodenum	1.00	infobox
CCL18	Bgee	spleen	1.00	infobox
CCL18	Bgee	gallbladder	1.00	infobox
CCL18	Bgee	right coronary artery	1.00	infobox
CCL18	Bgee	left coronary artery	1.00	infobox
CCL18	BioGPS	n/a	1.00	infobox
CCL18	Chr.	Chromosome 17 (human)	1.00	infobox
CCL18	Databases	NCBI: entry; OMA: entry	1.00	infobox
CCL18	End	36,072,032 bp	1.00	infobox
CCL18	Ensembl	ENSG00000275385 ENSG00000278167 ENSG00000278006	1.00	infobox
CCL18	Entrez	6362	1.00	infobox
CCL18	External IDs	OMIM: 603757; GeneCards: CCL18	1.00	infobox
CCL18	Gene location (Human)	Gene location (Human)Chr.Chromosome 17 (human)Band17q12Start36,064,272 bpEnd36,072,032 bp	1.00	infobox
CCL18	Gene ontology	cytokine activity	1.00	infobox
CCL18	Gene ontology	protein binding	1.00	infobox
CCL18	Gene ontology	CCR chemokine receptor binding	1.00	infobox
CCL18	Gene ontology	chemokine activity	1.00	infobox
CCL18	Gene ontology	extracellular region	1.00	infobox
CCL18	Gene ontology	extracellular space	1.00	infobox
CCL18	Gene ontology	G protein-coupled receptor signaling pathway	1.00	infobox
CCL18	Gene ontology	monocyte chemotaxis	1.00	infobox
CCL18	Gene ontology	chemokine-mediated signaling pathway	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CCL18 bring nearby vocabulary together. In this analysis, examples include Cells, Expressed and Immune. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CCL18
- Cells
- Expressed
- Immune
- Binding
- Functions
- T-cells
- T-helper
- Diseases
- Effector
- Furthermore
- Gene
- Immunosuppressive
ccl18
- Cells
- Expressed
- Immune
- Binding
- Functions
- T-cells
- T-helper
- Diseases
- Effector
- Furthermore
- Gene
- Immunosuppressive
cytokine
- Cell
- Immune
- Response
- Type
- Bp
- Chr
- Inflammatory
- Ligand
- Breast
- Cancer
- Chromosome
- Function
innate immune system
- System
- Bp
- Chr
- Breast
- Cancer
- Cell
- Chromosome
- Human
- Effector
- Gene
- Protein
- Involved
adaptive immune system
- System
- Bp
- Chr
- Breast
- Cancer
- Cell
- Chromosome
- Human
- Effector
- Gene
- Protein
- Involved
dendritic cells
- Cells
- Dendritic
- Effector
- Immunosuppressive
- T-cells
- B-cells
- Expressed
- Also
- Involved
- T-helper
- Immune
- Inflammatory
breast cancer
- Cancer
- Effector
- Binding
- Functions
- T-cells
- Receptor
- Immune
- Bp
- Cells
- Chr
- Ligand
- B-cells
effector functions
- Immunosuppressive
- T-cells
- Breast
- Cancer
- Immune
- Cells
- Effector
- Functions
- Protein
- System
- T-helper
- Bp

Connections between topic areas Semantic bridges

For CCL18, one of the stronger structural bridges in this analysis connects CCL18 with Sources. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CCL18 — Sources · splits 48 ⟂ 17

CCL18 — Receptor · splits 51 ⟂ 14

CCL18 — Gene and protein structure · splits 56 ⟂ 9

CCL18 — Overview · splits 57 ⟂ 8

CCL18 — Involvement in disease · splits 58 ⟂ 7

CCL18 — Effector functions · splits 60 ⟂ 5

CCL18 — Chemotactic functions · splits 61 ⟂ 4

Map overview Semantic statistics

CCL18

Nodes65

Edges64

Triples150

Avg. degree1.97

Density0.030769

Components1

Source & methodology

TTTA analyzes the structure around CCL18 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Receptor, Gene and protein structure & Involvement in disease, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CCL18 · EN edition · Analysis: TopicsToTalkAbout