Gla domain

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Gla domain topic overview

The analysis highlights Human proteins containing this domain, Functions and Subfamilies as prominent areas in the source structure around Gla domain. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics: 39
Source areas: 4
Connected nodes: 44
Extracted relationships: 27
Concept neighborhoods: 23
Bridge connections: 44

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Human proteins containing this domain · 24 topics

Overview · 11 topics

Functions · 3 topics

Subfamilies · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold: IPR000294 · PF00594
Available protein structures:: IPR000294 · PF00594
InterPro: IPR000294
Membranome: 342
OPM protein: 1pfx
OPM superfamily: 89

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Functions

Human proteins containing this domain

Thrombin
Coagulation
Factor VII
Factor IX
Factor X
Protein C
Anticoagulation
Inflammation
Cell death
Permeability of blood vessel walls Vascular permeability
Protein S
Bone mineralization
Matrix gla protein
Calcification
Transthyretin
Inter-alpha-trypsin inhibitor
ITIH2
Embryonic development Embryogenesis
Immune responses Immune system
Epithelial cells Epithelium
PRRG1 PRRG1?action=edit&redlink=1
PRRG2 PRRG2?action=edit&redlink=1
PRRG3 PRRG3?action=edit&redlink=1
PRRG4 PRRG4?action=edit&redlink=1

Subfamilies

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Gla domain connects Entity context

The extracted context around Gla domain shows recurring relationship patterns in the source. For example, Gla domain → Ciona, Despite, Gla, It, IX, Jagged1, PRGP1 Another extracted example is Gla domain → FVII, Gla, In, The, The Gla, There. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to In invertebrates · 7

Gla domain → Ciona, Despite, Gla, It, IX, Jagged1, PRGP1

related to Coagulation and anticoagulation proteins · 6

Gla domain → FVII, Gla, In, The, The Gla, There

AlphaFold · 2

Gla domain → IPR000294, PF00594

Available protein structures: · 2

Gla domain → IPR000294, PF00594

InterPro · 1

Gla domain → IPR000294

Membranome · 1

Gla domain → 342

OPM protein · 1

Gla domain → 1pfx

OPM superfamily · 1

Gla domain → 89

PDB · 1

Gla domain → IPR000294 PF00594 (ECOD; PDBsum)

Pfam · 1

Gla domain → PF00594

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gla coagulation domain proteins protein residues factor blood cell calcium ions bone matrix domains membrane calcification ix form known necessary

Gla domain relationships Subject–Predicate–Object triples

TTTA extracted 27 structured relationships around Gla domain. Examples in this analysis include Gla domain → AlphaFold → IPR000294 and Gla domain → AlphaFold → PF00594. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Gla domain	AlphaFold	IPR000294	1.00	infobox
Gla domain	AlphaFold	PF00594	1.00	infobox
Gla domain	Available protein structures:	IPR000294	1.00	infobox
Gla domain	Available protein structures:	PF00594	1.00	infobox
Gla domain	InterPro	IPR000294	1.00	infobox
Gla domain	Membranome	342	1.00	infobox
Gla domain	OPM protein	1pfx	1.00	infobox
Gla domain	OPM superfamily	89	1.00	infobox
Gla domain	PDB	IPR000294 PF00594 (ECOD; PDBsum)	1.00	infobox
Gla domain	Pfam	PF00594	1.00	infobox
Gla domain	PROSITE	PDOC00011	1.00	infobox
Gla domain	SCOP2	1cfi / SCOPe / SUPFAM	1.00	infobox
Gla domain	Symbol	Gla	1.00	infobox
Gla domain	causes	a binding affinity to phosphatidylserine	0.90	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Gla domain bring nearby vocabulary together. In this analysis, examples include Proteins, Gla and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Gla domain
- Proteins
- Gla
- Protein
- Coagulation
- Found
- Residues
- Blood
- Bone
- Factor
- Matrix
- Calcification
- Calcium
gla domain
- Proteins
- Gla
- Protein
- Coagulation
- Found
- Residues
- Membrane
- Blood
- Bone
- Factor
- Matrix
- Calcification
protein domain
- Bone
- Factor
- Matrix
- Proteins
- Gla
- Calcification
- Coagulation
- Blood
- Found
- Ix
- Mgp
- Mineralization
protein z
- Bone
- Factor
- Matrix
- Calcification
- Coagulation
- Blood
- Ix
- Mgp
- Mineralization
- Osteocalcin
- Cell
- Vertebrate
matrix gla protein
- Mgp
- Osteocalcin
- Bone
- Calcification
- Factor
- Matrix
- Protein
- Proteins
- Periostin
- Prothrombin
- Regulating
- Vii
cell growth
- Mgp
- Blood
- Bone
- Factor
- Gas6
- Ii
- Matrix
- Periostin
- Prothrombin
- Regulating
- Vii
- Ix
coagulation
- Factor
- Proteins
- Domain
- Protein
- Gla
- Ix
- Mgp
- Calcification
- Membrane
- Bone
- Matrix
- Anticoagulation
factor vii
- Ii
- Prothrombin
- Regulating
- Ix
- Mgp
- Osteocalcin
- Calcification
- Cell
- Protein
- Bone
- Matrix
- Anticoagulation

Connections between topic areas Semantic bridges

For Gla domain, one of the stronger structural bridges in this analysis connects Gla domain with Human proteins containing this domain. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Gla domain — Human proteins containing this domain · splits 20 ⟂ 25

Gla domain — Overview · splits 33 ⟂ 12

Gla domain — Functions · splits 41 ⟂ 4

Gla domain — Subfamilies · splits 42 ⟂ 3

Map overview Semantic statistics

Gla domain

Nodes45

Edges44

Triples27

Avg. degree1.96

Density0.044444

Components1

Source & methodology

TTTA analyzes the structure around Gla domain to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Human proteins containing this domain, Functions & Subfamilies, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Gla domain · EN edition · Analysis: TopicsToTalkAbout