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GAS6: Interactions, Function & Overview

Growth arrest – specific 6, also known as GAS6, is both a human gene and the protein it codes for. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts.

Language: English [EN]
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GAS6 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around GAS6.

Related topics
11
Source areas
3
Connected nodes
14
Extracted relationships
159
Concept neighborhoods
9
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 8 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GAS6, AXLLG, AXSF, growth arrest specific 6
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H30, 2C5D, 4RA0
Band
13q34 · 8 A1.1|8 6.06 cM
Bgee
ascending aorta · Descending thoracic aorta · right uterine tube · right coronary artery · canal of the cervix
BioGPS
n/a
Chr.
Chromosome 13 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GAS6 connects Entity context

The extracted context around GAS6 shows recurring relationship patterns in the source. For example, GAS6 → activation of protein kinase B activity, animal organ regeneration, apoptotic cell clearance, apoptotic process, B cell chemotaxis, blood coagulation, calcium ion binding, calcium ion transmembrane transport, cell adhesion, cell migration, cell population proliferation, cell-substrate adhesion, cellular response to glucose stimulus, cellular response to growth factor stimulus, cellular response to interferon-alpha, cellular response to starvation, cellular response to vitamin K, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytoplasm, dendritic cell differentiation Another extracted example is GAS6 → ankle, apex of heart, ascending aorta, body of uterus, calvaria, canal of the cervix, choroid plexus of fourth ventricle, Descending thoracic aorta, epithelium of stomach, gallbladder, left uterine tube, lip, popliteal artery, right coronary artery, right kidney, right lung, right uterine tube, skin of external ear, stroma of bone marrow, tibial arteries. Use these groups to spot repeated connection types before inspecting the individual relationships.

GAS6

Top relations

Gene ontology · 89
GAS6 → activation of protein kinase B activity, animal organ regeneration, apoptotic cell clearance, apoptotic process, B cell chemotaxis, blood coagulation, calcium ion binding, calcium ion transmembrane transport, cell adhesion, cell migration, cell population proliferation, cell-substrate adhesion, cellular response to glucose stimulus, cellular response to growth factor stimulus, cellular response to interferon-alpha, cellular response to starvation, cellular response to vitamin K, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytoplasm, dendritic cell differentiation
Bgee · 20
GAS6 → ankle, apex of heart, ascending aorta, body of uterus, calvaria, canal of the cervix, choroid plexus of fourth ventricle, Descending thoracic aorta, epithelium of stomach, gallbladder, left uterine tube, lip, popliteal artery, right coronary artery, right kidney, right lung, right uterine tube, skin of external ear, stroma of bone marrow, tibial arteries
RNA expression pattern · 20
GAS6 → ankle, apex of heart, ascending aorta, body of uterus, calvaria, canal of the cervix, choroid plexus of fourth ventricle, Descending thoracic aorta, epithelium of stomach, gallbladder, left uterine tube, lip, popliteal artery, right coronary artery, right kidney, right lung, right uterine tube, skin of external ear, stroma of bone marrow, tibial arteries
related to Interactions · 6
GAS6 → AXL, Gla, K-dependent, MerTK, The, TYRO3
Band · 2
GAS6 → 13q34, 8 A1.1|8 6.06 cM
Chr. · 2
GAS6 → Chromosome 13 (human), Chromosome 8 (mouse)
End · 2
GAS6 → 113,864,076 bp, 13,544,490 bp
Aliases · 1
GAS6 → GAS6, AXLLG, AXSF, growth arrest specific 6
Available structures · 1
GAS6 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H30, 2C5D, 4RA0
BioGPS · 1
GAS6 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human gene bp protein chr band growth chromosome 13 location function mouse vitamin arrest specific codes acid external search 864

GAS6 relationships Subject–Predicate–Object triples

TTTA extracted 159 structured relationships around GAS6. Examples in this analysis include GAS6 → Aliases → GAS6, AXLLG, AXSF, growth arrest specific 6 and GAS6 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H30, 2C5D, 4RA0. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GAS6AliasesGAS6, AXLLG, AXSF, growth arrest specific 61.00infobox
GAS6Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H30, 2C5D, 4RA01.00infobox
GAS6Band13q341.00infobox
GAS6Band8 A1.1|8 6.06 cM1.00infobox
GAS6Bgeeascending aorta1.00infobox
GAS6BgeeDescending thoracic aorta1.00infobox
GAS6Bgeeright uterine tube1.00infobox
GAS6Bgeeright coronary artery1.00infobox
GAS6Bgeecanal of the cervix1.00infobox
GAS6Bgeeapex of heart1.00infobox
GAS6Bgeebody of uterus1.00infobox
GAS6Bgeeleft uterine tube1.00infobox
GAS6Bgeepopliteal artery1.00infobox
GAS6Bgeetibial arteries1.00infobox
GAS6Bgeestroma of bone marrow1.00infobox
GAS6Bgeecalvaria1.00infobox
GAS6Bgeechoroid plexus of fourth ventricle1.00infobox
GAS6Bgeegallbladder1.00infobox
GAS6Bgeeankle1.00infobox
GAS6Bgeeskin of external ear1.00infobox
GAS6Bgeeright kidney1.00infobox
GAS6Bgeelip1.00infobox
GAS6Bgeeepithelium of stomach1.00infobox
GAS6Bgeeright lung1.00infobox
GAS6BioGPSn/a1.00infobox
GAS6Chr.Chromosome 13 (human)1.00infobox
GAS6Chr.Chromosome 8 (mouse)1.00infobox
GAS6DatabasesNCBI: entry; OMA: entry1.00infobox
GAS6End113,864,076 bp1.00infobox
GAS6End13,544,490 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GAS6 bring nearby vocabulary together. In this analysis, examples include Function, Growth and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GAS6
    • Function
    • Growth
    • Gene
    • Human
    • Codes
    • External
    • Kinase
    • Receptor
    • Search
    • Specific
    • Tyrosine
    • Location
  • gas6
    • Function
    • Growth
    • Gene
    • Human
    • Codes
    • External
    • Kinase
    • Receptor
    • Search
    • Specific
    • Tyrosine
    • Location
  • gene
    • Growth
    • Human
    • Location
    • Chromosome
    • Bp
    • Chr
    • A1
    • Codes
    • End
    • External
    • Mouse
    • Search
  • protein s
    • Acid
    • Endoplasmic
    • Gla
    • Production
    • Reticulum
    • Vitamin
    • Cell
    • Involved
    • Proliferation
    • A1
    • End
    • External
  • gamma-carboxyglutamic acid (gla) domain
    • Production
    • Reticulum
    • Vitamin
    • Cell
    • Involved
    • Proliferation
    • Protein
    • A1
    • End
    • Endoplasmic
    • External
    • Gla
  • vitamin k
    • Endoplasmic
    • Gla
    • Production
    • Reticulum
    • Function
    • Protein
    • Cell
    • Gas6
    • Involved
    • Proliferation
    • A1
    • Acid
  • function
    • External
    • Search
    • Gas6
    • Location
    • Vitamin
    • Chromosome
    • Growth
    • Bp
    • Cell
    • Chr
    • Gene
    • Human
  • endoplasmic reticulum
    • Gla
    • Production
    • Reticulum
    • Vitamin
    • Involved
    • Proliferation
    • Protein
    • External
    • Kinase
    • Mouse
    • Receptor
    • Search

Connections between topic areas Semantic bridges

For GAS6, one of the stronger structural bridges in this analysis connects GAS6 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GAS6 — Interactions · splits 6 ⟂ 9
GAS6 — Overview · splits 12 ⟂ 3

Map overview Semantic statistics

GAS6

Nodes15
Edges14
Triples159
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around GAS6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GAS6 · EN edition · Analysis: TopicsToTalkAbout

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