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Genome editing: Technology, History, Applications & Research

Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions to site-specific locations.

Language: English [EN]
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Genome editing topic overview

The analysis highlights Technology, History, Applications and Research as prominent areas in the source structure around Genome editing. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
156
Source areas
11
Connected nodes
168
Extracted relationships
234
Concept neighborhoods
44
Bridge connections
168

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 59 topics
History · 26 topics
Applications · 17 topics
Research · 17 topics
Prospects and limitations · 13 topics
Risks · 9 topics
Process · 5 topics
Background · 3 topics
Multiplex Automated Genomic Engineering (MAGE) · 3 topics
Nobel prize · 3 topics
Precision and efficiency of engineered nucleases · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Background

Process

Precision and efficiency of engineered nucleases

Multiplex Automated Genomic Engineering (MAGE)

Applications

Research

Prospects and limitations

Risks

Nobel prize

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Genome editing connects Entity context

The extracted context around Genome editing shows recurring relationship patterns in the source. For example, Genome editing → Academic Press, April, B978-0-443-19045-2, Bioethics, Chapter, Clinical Ethics At, Connor, Crop Improvement, Crossroads, Customized Human Genes, Daniela, From, Genetic, Genomic, Human Germline Editing, Iancu, In Hostiuc, ISBN, March, New Promises Another extracted example is Genome editing → Arabidopsis, Calyxt, CRISPR/Cas9, For, Genome, In, In Arabidopsis, In Zea, IPK1, Meganuclease, Musa, NHEJ, PAT, Progress, Such, SuR, SuRA, SuRB, TALEN, TALEN-based. Use these groups to spot repeated connection types before inspecting the individual relationships.

Genome editing

Top relations

related to Further reading · 33
Genome editing → Academic Press, April, B978-0-443-19045-2, Bioethics, Chapter, Clinical Ethics At, Connor, Crop Improvement, Crossroads, Customized Human Genes, Daniela, From, Genetic, Genomic, Human Germline Editing, Iancu, In Hostiuc, ISBN, March, New Promises
related to Targeted gene modification in plants · 25
Genome editing → Arabidopsis, Calyxt, CRISPR/Cas9, For, Genome, In, In Arabidopsis, In Zea, IPK1, Meganuclease, Musa, NHEJ, PAT, Progress, Such, SuR, SuRA, SuRB, TALEN, TALEN-based
related to Risks · 23
Genome editing → According, Australia, Australian, Bioethics, Clapper, CRISPR, For, Furthermore, Ian Ramshaw, In, James, Journal, National Intelligence, Nuffield Council, Ronald Jackson, September, Such, The, United States Director, US Intelligence Community
related to Human enhancement · 16
Genome editing → According, Alzheimer's, Australian, Bioethics, February, Genetics David Andrew Sinclair, George Church, Many, Medicine, National Academy, Nuffield Council, Professor, Sciences, September, The American National Academy, They
related to Multiplex Automated Genomic Engineering (MAGE) · 14
Genome editing → By, Chemically, DNA, Each, Experiments, Harvard University, It, MAGE, Prior, The, There, Therefore, Those, Wyss Institute
related to history · 13
Genome editing → All, As, Breakthrough, CRISPR-Cas, Genome, In, Method, Nature Methods, Nine, Science, TALEN, Year, ZFNs
related to Targeted gene modification in animals · 13
Genome editing → Atlantic, Cas9, CDI, CRISPR/Cas9, Furthermore, Gene, In, Knockouts, KO, RNA-guided, RNAs, Selecting, The
related to Engineered nucleases · 11
Genome editing → Clustered, Commonly, CRISPR/Cas9, DNA, DSB, MeganucleasesZinc, TALEN, The, To, Transcription-activator, ZFNs
related to Nobel prize · 10
Genome editing → Chemistry, Emmanuelle Charpentier, In, Jennifer Doudna, Mario Capecchi, Martin Evans, Medicine, Nobel Prize, Oliver Smithies, Physiology
has application · 8
Genome editing → As, For, Genome, In, Listed, TALEN-based, The, ZFN-mediated

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

genome dna editing gene crispr nucleases used specific sequence talen proteins sequences genetic zinc human engineered genes cells one methods

Genome editing relationships Subject–Predicate–Object triples

TTTA extracted 234 structured relationships around Genome editing. Examples in this analysis include Zinc finger nuclease → instance of → a severe monogenic disorder that predisposes the patients to skin cancer and burns whenever their skin is exposed to UV rays.Meganucleases have the benefit of causing less toxic… and transcription factors → instance of → Cys2-His2 Zinc fingers typically happen in repeats that are 3 bp apart and are found in diverse combinations in a variety of nucleic acid interacting proteins. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Zinc finger nucleaseinstance ofa severe monogenic disorder that predisposes the patients to skin cancer and burns whenever their skin is exposed to UV rays.Meganucleases have the benefit of causing less toxic…0.80text
transcription factorsinstance ofCys2-His2 Zinc fingers typically happen in repeats that are 3 bp apart and are found in diverse combinations in a variety of nucleic acid interacting proteins0.80text
modular assemblyinstance ofZinc fingers have been more established in these terms and approaches0.80text
sequence insertioninstance offor gene editing applications that enable to perform targeted genome modifications0.80text
deletioninstance offor gene editing applications that enable to perform targeted genome modifications0.80text
repairinstance offor gene editing applications that enable to perform targeted genome modifications0.80text
replacement in living cellsinstance offor gene editing applications that enable to perform targeted genome modifications0.80text
zinc fingersinstance ofwhich can then be linked to specific DNA sequence recognizing peptides0.80text
transcription activator-like effectorsinstance ofwhich can then be linked to specific DNA sequence recognizing peptides0.80text
Atlantic salmoninstance ofgene editing can be applied to certain types of fish in aquaculture0.80text
Down syndromeinstance ofand to evade detection by the host immune system after introduction.Extensive research has been done in cells and animals using CRISPR-Cas9 to attempt to correct genetic mutatio…0.80text
spina bifidainstance ofand to evade detection by the host immune system after introduction.Extensive research has been done in cells and animals using CRISPR-Cas9 to attempt to correct genetic mutatio…0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Genome editing bring nearby vocabulary together. In this analysis, examples include Genome, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Genome editing
    • Genome
    • Gene
    • Human
    • Engineering
    • Engineered
    • Genetic
    • Genes
    • Also
    • Targeted
    • Nucleases
    • Crispr
    • Specific
  • genome editing
    • Genome
    • Gene
    • Human
    • Engineering
    • Engineered
    • Genetic
    • Genes
    • Also
    • Crispr
    • Targeted
    • Using
    • Nucleases
  • genetic engineering
    • Genetic
    • Targeted
    • Genome
    • Also
    • Cells
    • Efficiency
    • Research
    • Method
    • Nucleases
    • Using
    • Finger
    • Homologous
  • dna
    • Sequence
    • Sequences
    • Proteins
    • Talen
    • Targeted
    • Cells
    • Zinc
    • Specific
    • Zfns
    • Genome
    • Nucleases
    • Meganucleases
  • genome
    • Human
    • Engineered
    • Genes
    • Targeted
    • Nucleases
    • Crispr
    • Specific
    • Research
    • Methods
    • One
    • Cells
    • Used
  • genetic engineering techniques
    • Genetic
    • Targeted
    • Genome
    • Also
    • Cells
    • Efficiency
    • Research
    • Method
    • Nucleases
    • Using
    • Finger
    • Homologous
  • crispr gene editing
    • Genome
    • Gene
    • Human
    • Cells
    • Genes
    • Proteins
    • Talen
    • Targeting
    • Using
    • Engineering
    • Research
    • Also
  • base editing
    • Genome
    • Gene
    • Human
    • Engineering
    • Genetic
    • Also
    • Crispr
    • Engineered
    • Using
    • Nucleases
    • Methods
    • Specific

Connections between topic areas Semantic bridges

For Genome editing, one of the stronger structural bridges in this analysis connects Genome editing with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Genome editingOverview · splits 109 ⟂ 60
Genome editingHistory · splits 142 ⟂ 27
Genome editingApplications · splits 151 ⟂ 18
Genome editingResearch · splits 151 ⟂ 18
Genome editingProspects and limitations · splits 155 ⟂ 14
Genome editingRisks · splits 159 ⟂ 10
Genome editingProcess · splits 163 ⟂ 6
Genome editingBackground · splits 165 ⟂ 4
Genome editingMultiplex Automated Genomic Engineering (MAGE) · splits 165 ⟂ 4
Genome editingNobel prize · splits 165 ⟂ 4
Genome editingPrecision and efficiency of engineered nucleases · splits 166 ⟂ 3

Map overview Semantic statistics

Genome editing

Nodes169
Edges168
Triples234
Avg. degree1.99
Density0.011834
Components1

Source & methodology

TTTA analyzes the structure around Genome editing to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Technology, History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Genome editing · EN edition · Analysis: TopicsToTalkAbout

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