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FokI: Exploitation & Overview

The restriction endonuclease Fok1, naturally found in Flavobacterium okeanokoites, is a bacterial type IIS restriction endonuclease consisting of an N-terminal DNA-binding domain and a non sequence-specific DNA cleavage domain at the C-terminal. Once the protein is bound to duplex DNA via its DNA-binding domain at the 5'-GGATG-3' recognition site, the…

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FokI topic overview

The analysis highlights Exploitation and Overview as prominent areas in the source structure around FokI.

Related topics
16
Source areas
2
Connected nodes
18
Extracted relationships
11
Concept neighborhoods
12
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics
Exploitation · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR015334 · PF09254
Available protein structures:
IPR015334 · PF09254
InterPro
IPR015334
PDB
IPR015334 PF09254 (ECOD; PDBsum)
Pfam
PF09254
Pfam clan
CL0415

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Exploitation

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FokI connects Entity context

The extracted context around FokI shows recurring relationship patterns in the source. For example, FokI → IPR015334, PF09254 Another extracted example is FokI → IPR015334. Use these groups to spot repeated connection types before inspecting the individual relationships.

FokI

Top relations

AlphaFold · 2
FokI → IPR015334, PF09254
Available protein structures: · 2
FokI → IPR015334, PF09254
InterPro · 1
FokI → IPR015334
PDB · 1
FokI → IPR015334 PF09254 (ECOD; PDBsum)
Pfam · 1
FokI → PF09254
Pfam clan · 1
FokI → CL0415
SCOP2 · 1
FokI → 2fok / SCOPe / SUPFAM
Symbol · 1
FokI → Endonuc-Fok1_C

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

domain dna dna-binding cleavage endonuclease protein recognition two fok1 bound site cut restriction nuclease nucleotide see also flavobacterium n-terminal c-terminal

FokI relationships Subject–Predicate–Object triples

TTTA extracted 11 structured relationships around FokI. Examples in this analysis include FokI → AlphaFold → IPR015334 and FokI → AlphaFold → PF09254. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FokIAlphaFoldIPR0153341.00infobox
FokIAlphaFoldPF092541.00infobox
FokIAvailable protein structures:IPR0153341.00infobox
FokIAvailable protein structures:PF092541.00infobox
FokIInterProIPR0153341.00infobox
FokIPDBIPR015334 PF09254 (ECOD; PDBsum)1.00infobox
FokIPfamPF092541.00infobox
FokIPfam clanCL04151.00infobox
FokISCOP22fok / SCOPe / SUPFAM1.00infobox
FokISymbolEndonuc-Fok1_C1.00infobox
the zinc fingerinstance ofafter combination with a variety of DNA-binding domains0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around FokI bring nearby vocabulary together. In this analysis, examples include Bacterial, C-terminal and Consisting. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • restriction endonuclease
    • Dna-binding
    • Fok1
    • C-terminal
    • Consisting
    • Domain
    • Gene
    • Iis
    • N-terminal
    • Non
    • Restriction
    • See
    • Sequence-specific
  • dna-binding domain
    • Endonuclease
    • Cleavage
    • Domain
    • Fok1
    • Dna
    • Recognition
    • Gene
    • Nucleotide
    • Restriction
    • See
    • Bound
    • Site
  • dna-binding domains
    • Endonuclease
    • Domain
    • Fok1
    • Dna
    • Recognition
    • Gene
    • Nucleotide
    • Restriction
    • See
    • Bound
    • Nuclease
    • Protein
  • flavobacterium
    • Bacterial
    • C-terminal
    • Consisting
    • Found
    • Iis
    • N-terminal
    • Naturally
    • Non
    • Okeanokoites
    • Sequence-specific
    • Type
    • Restriction
  • c-terminal
    • Consisting
    • Flavobacterium
    • Found
    • Iis
    • N-terminal
    • Naturally
    • Non
    • Okeanokoites
    • Sequence-specific
    • Type
    • Restriction
    • Fok1
  • zinc finger nuclease
    • Finger
    • Zinc
    • Nuclease
    • Gene
    • Nucleotide
    • See
    • Fok1
    • Protein
    • Upon
    • Endonuclease
    • Site
    • Dna-binding
  • n-terminal
    • C-terminal
    • Naturally
    • Non
    • Okeanokoites
    • Sequence-specific
    • Type
    • Restriction
    • Cleavage
    • Dna-binding
    • Dna
    • Domain
  • duplex
    • 5'-ggatg-3'
    • Activated
    • Cleaves
    • Locations
    • Via
    • Cut
    • Nucleotide
    • Protein
    • Site
    • Two
    • Recognition

Connections between topic areas Semantic bridges

For FokI, one of the stronger structural bridges in this analysis connects FokI with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FokIOverview · splits 8 ⟂ 11
FokIExploitation · splits 12 ⟂ 7

Map overview Semantic statistics

FokI

Nodes19
Edges18
Triples11
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around FokI to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Exploitation & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FokI · EN edition · Analysis: TopicsToTalkAbout

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