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Connexon

In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells. This channel allows for bidirectional flow of ions and signaling molecules. The connexon is the hemichannel supplied by a cell on one side of the junction; two…

Structure, Cellular functions & Related diseases

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Latin
connexona
TH
H1.00.01.1.02025

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Structure

Cellular functions

Overall functions

Related diseases

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Map overview Semantic statistics

Connexon

Nodes70
Edges69
Triples76
Avg. degree1.97
Density0.028571
Components1

How this topic connects Entity context

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Connexon

Top relations

related to Modulation · 12
Connexon → Another, C-terminal, Ca2, Chemical, Communication, Golgi Apparatus, Humoral, It, Neurotransmitters, Protein Phosphorylation, The, These
related to Overall functions · 11
Connexon → Along, ATP, CNS, Connexons, Further, In, Many, Other, Recent, Specifically, The
related to Related diseases · 11
Connexon → Additionally, Cardiovascular, Cx43, Gap, However, II, In, Overall, Some, The, This
related to General · 10
Connexon → Connexin, Connexins, Connexons, Cx, During, Early, In, Since, Structurally, Subsequently
related to Degradation · 7
Connexon → Connexons, In, It, Lysosomes, Now, Research, This
related to Properties · 4
Connexon → Channels, Gates, Research, The
related to Assembly · 3
Connexon → Connexons, The, These
Latin · 1
Connexon → connexona
TH · 1
Connexon → H1.00.01.1.02025
is a · 1
Connexon → hemichannel supplied by a cell on one side of the junction

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Important terminology

connexons gap junction cells connexins cell connexin membrane channel heart role diabetes type signaling channels also form hemichannel junctions disease

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ConnexonLatinconnexona1.00infobox
ConnexonTHH1.00.01.1.020251.00infobox
Connexonis ahemichannel supplied by a cell on one side of the junction0.90text
charge selectivityinstance ofThe permeability and selectivity of the channels is determined by its width as well as the molecular selectivity of connexins0.80text
neurotransmittersinstance ofhumoral modulation of gap junction communication is done through many biomolecules0.80text
growth factorsinstance ofhumoral modulation of gap junction communication is done through many biomolecules0.80text
and various bioactive compoundsinstance ofhumoral modulation of gap junction communication is done through many biomolecules0.80text
epinephrineinstance ofNeurotransmitters0.80text
norepinephrine work in neuronal gap-junctions causing propagation of action potentials down neuronsinstance ofNeurotransmitters0.80text
epilepsyinstance ofconnexons play a major role in conditions0.80text
ischemiainstance ofconnexons play a major role in conditions0.80text
inflammationinstance ofconnexons play a major role in conditions0.80text

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