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GJD2: Function & Overview

Gap junction delta-2 protein (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9), is a protein that in humans is encoded by the GJD2 gene.

Language: English [EN]
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GJD2 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around GJD2.

Related topics
3
Source areas
2
Connected nodes
5
Extracted relationships
77
Related term clusters
5
Bridge connections
5

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GJD2, CX36, GJA9, gap junction protein delta 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2N6A
Band
15q14 · 2|2 E4
Bgee
islet of Langerhans · gonad · pituitary gland · anterior pituitary · prefrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 2 (mouse)

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GJD2
3Protein · Gene · GJB2

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How GJD2 connects Entity context

The extracted context around GJD2 shows recurring relationship patterns in the source. For example, GJD2 → anterior horn of spinal cord, anterior pituitary, body of pancreas, Brodmann area 9, dorsolateral prefrontal cortex, facial motor nucleus, gonad, islet of Langerhans, lumbar subsegment of spinal cord, neural layer of retina, occipital lobe, olfactory bulb, pineal gland, pituitary gland, prefrontal cortex, retinal pigment epithelium, right auricle of heart, stellate ganglion, thoracic ganglia Another extracted example is GJD2 → action potential, cell communication, cell junction, cell-cell signaling, chemical synaptic transmission, connexin complex, gap junction, gap junction channel activity, integral component of membrane, membrane, plasma membrane, transmembrane transport, visual perception. Use these groups to spot repeated connection types before inspecting the individual relationships.

GJD2

Top relations

Bgee · 19
GJD2 → anterior horn of spinal cord, anterior pituitary, body of pancreas, Brodmann area 9, dorsolateral prefrontal cortex, facial motor nucleus, gonad, islet of Langerhans, lumbar subsegment of spinal cord, neural layer of retina, occipital lobe, olfactory bulb, pineal gland, pituitary gland, prefrontal cortex, retinal pigment epithelium, right auricle of heart, stellate ganglion, thoracic ganglia
RNA expression pattern · 19
GJD2 → anterior horn of spinal cord, anterior pituitary, body of pancreas, Brodmann area 9, dorsolateral prefrontal cortex, facial motor nucleus, gonad, islet of Langerhans, lumbar subsegment of spinal cord, neural layer of retina, occipital lobe, olfactory bulb, pineal gland, pituitary gland, prefrontal cortex, retinal pigment epithelium, right auricle of heart, stellate ganglion, thoracic ganglia
Gene ontology · 13
GJD2 → action potential, cell communication, cell junction, cell-cell signaling, chemical synaptic transmission, connexin complex, gap junction, gap junction channel activity, integral component of membrane, membrane, plasma membrane, transmembrane transport, visual perception
related to Function · 3
GJD2 → Connexins, CX36, See GJB2
Band · 2
GJD2 → 15q14, 2|2 E4
Chr. · 2
GJD2 → Chromosome 15 (human), Chromosome 2 (mouse)
End · 2
GJD2 → 113,844,100 bp, 34,754,998 bp
Aliases · 1
GJD2 → GJD2, CX36, GJA9, gap junction protein delta 2
Available structures · 1
GJD2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2N6A
BioGPS · 1
GJD2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band gap junction protein chromosome 15 cx36 location mouse gja9 function external pdb uniprot q9ukl4 delta-2

GJD2 relationships Subject–Predicate–Object triples

TTTA extracted 77 structured relationships around GJD2. Examples in this analysis include GJD2 → Aliases → GJD2, CX36, GJA9, gap junction protein delta 2 and GJD2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2N6A. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GJD2AliasesGJD2, CX36, GJA9, gap junction protein delta 21.00infobox
GJD2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2N6A1.00infobox
GJD2Band15q141.00infobox
GJD2Band2|2 E41.00infobox
GJD2Bgeeislet of Langerhans1.00infobox
GJD2Bgeegonad1.00infobox
GJD2Bgeepituitary gland1.00infobox
GJD2Bgeeanterior pituitary1.00infobox
GJD2Bgeeprefrontal cortex1.00infobox
GJD2Bgeeright auricle of heart1.00infobox
GJD2Bgeebody of pancreas1.00infobox
GJD2Bgeeoccipital lobe1.00infobox
GJD2Bgeedorsolateral prefrontal cortex1.00infobox
GJD2BgeeBrodmann area 91.00infobox
GJD2Bgeethoracic ganglia1.00infobox
GJD2Bgeeneural layer of retina1.00infobox
GJD2Bgeelumbar subsegment of spinal cord1.00infobox
GJD2Bgeestellate ganglion1.00infobox
GJD2Bgeeanterior horn of spinal cord1.00infobox
GJD2Bgeefacial motor nucleus1.00infobox
GJD2Bgeepineal gland1.00infobox
GJD2Bgeeolfactory bulb1.00infobox
GJD2Bgeeretinal pigment epithelium1.00infobox
GJD2BioGPSMore reference expression data1.00infobox
GJD2Chr.Chromosome 15 (human)1.00infobox
GJD2Chr.Chromosome 2 (mouse)1.00infobox
GJD2DatabasesNCBI: entry; OMA: entry1.00infobox
GJD2End34,754,998 bp1.00infobox
GJD2End113,844,100 bp1.00infobox
GJD2EnsemblENSG000001592481.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around GJD2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GJD2
    • Gene
    • Protein
    • Function
    • Gja9
    • Search
    • Junction
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Connexin
  • gjd2
    • Gene
    • Protein
    • Function
    • Gja9
    • Search
    • Junction
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Connexin
  • gene
    • Gjd2
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • End
    • Function
    • Gja9
    • Junction
    • Mouse
  • function
    • Search
    • Gjd2
    • Location
    • Chromosome
    • Connexin
    • Expressed
    • Gene
    • Human
    • Protein
    • Bp
    • Chr
    • Gap
  • protein
    • Pdb
    • Q9ukl4
    • Search
    • Uniprot
    • Location
    • Connexin
    • Expressed
    • Channel
    • End
    • Information
    • Mouse
    • Band

Connections between topic areas Semantic bridges

For GJD2, one of the stronger structural bridges in this analysis connects GJD2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GJD2 — Overview · splits 3 ⟂ 3

Map overview Semantic statistics

GJD2

Nodes6
Edges5
Triples77
Avg. degree1.67
Density0.333333
Components1

Source & methodology

TTTA analyzes the structure around GJD2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GJD2 · EN edition · Analysis: TopicsToTalkAbout

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