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Frequency (gene): Regulation, Discovery & Structure and function

The frequency (frq) gene encodes the protein frequency (FRQ) that functions in the Neurospora crassa circadian clock. The FRQ protein plays a key role in circadian oscillator, serving to nucleate the negative element complex in the auto regulatory transcription-translation negative feedback-loop (TTFL) that is responsible for circadian rhythms in N.…

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Frequency (gene) topic overview

The analysis highlights Regulation, Discovery and Structure and function as prominent areas in the source structure around Frequency (gene).

Related topics
59
Source areas
6
Connected nodes
65
Extracted relationships
11
Concept neighborhoods
24
Bridge connections
65

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Regulation · 16 topics
Discovery · 13 topics
Structure and function · 13 topics
Evolution · 7 topics
Overview · 6 topics
FRQ-less oscillator (FLO) · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR018554 · PF09421
Available protein structures:
IPR018554 · PF09421
InterPro
IPR018554
PDB
IPR018554 PF09421 (ECOD; PDBsum)
Pfam
PF09421
Symbol
FRQ

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Structure and function

Regulation

FRQ-less oscillator (FLO)

Evolution

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Frequency (gene) connects Entity context

The extracted context around Frequency (gene) shows recurring relationship patterns in the source. For example, Frequency (gene) → IPR018554, PF09421 Another extracted example is Frequency (gene) → IPR018554. Use these groups to spot repeated connection types before inspecting the individual relationships.

Frequency (gene)

Top relations

AlphaFold · 2
Frequency (gene) → IPR018554, PF09421
Available protein structures: · 2
Frequency (gene) → IPR018554, PF09421
InterPro · 1
Frequency (gene) → IPR018554
PDB · 1
Frequency (gene) → IPR018554 PF09421 (ECOD; PDBsum)
Pfam · 1
Frequency (gene) → PF09421
Symbol · 1
Frequency (gene) → FRQ

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

frq circadian clock neurospora protein gene wcc expression period crassa oscillator element complex transcription function drosophila although feedback proteins kinase

Frequency (gene) relationships Subject–Predicate–Object triples

TTTA extracted 11 structured relationships around Frequency (gene). Examples in this analysis include Frequency (gene) → AlphaFold → IPR018554 and Frequency (gene) → AlphaFold → PF09421. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Frequency (gene)AlphaFoldIPR0185541.00infobox
Frequency (gene)AlphaFoldPF094211.00infobox
Frequency (gene)Available protein structures:IPR0185541.00infobox
Frequency (gene)Available protein structures:PF094211.00infobox
Frequency (gene)InterProIPR0185541.00infobox
Frequency (gene)PDBIPR018554 PF09421 (ECOD; PDBsum)1.00infobox
Frequency (gene)PfamPF094211.00infobox
Frequency (gene)SymbolFRQ1.00infobox
casein kinase 1ainstance ofwith some phosphorylations serving to lengthen period and others to shorten period.FRQ recruits kinases0.80text
temperature compensationinstance ofAlthough this FRQ-less rhythm lost certain clock characteristics0.80text
temperature pulses were sufficient to reset the clockinstance ofAlthough this FRQ-less rhythm lost certain clock characteristics0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Frequency (gene) bring nearby vocabulary together. In this analysis, examples include Transcription, Expression and Neurospora. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • circadian rhythms
    • Clock
    • Gene
    • Neurospora
    • Oscillator
    • Temperature
    • Strains
    • Frq
    • Crassa
    • Drosophila
    • Found
    • Light
    • Similar
  • circadian clock
    • Clock
    • Gene
    • Neurospora
    • Oscillator
    • Strains
    • Frq
    • Crassa
    • Protein
    • Function
    • Used
    • Expression
    • Drosophila
  • gene expression
    • Transcription
    • Expression
    • Gene
    • Wcc
    • Strains
    • Shown
    • Two
    • Neurospora
    • Negative
    • Element
    • Feedback
    • Protein
  • circadian
    • Clock
    • Gene
    • Neurospora
    • Oscillator
    • Strains
    • Frq
    • Crassa
    • Used
    • Protein
    • Expression
    • Found
    • Rhythms
  • Frequency (gene)
    • Transcription
    • Expression
    • Neurospora
    • Negative
    • Shown
    • Element
    • Feedback
    • Protein
    • Function
    • Wcc
    • Codon
    • Drosophila
  • frequency (gene)
    • Transcription
    • Expression
    • Neurospora
    • Negative
    • Shown
    • Element
    • Feedback
    • Protein
    • Function
    • Wcc
    • Codon
    • Drosophila
  • gene
    • Transcription
    • Expression
    • Neurospora
    • Negative
    • Shown
    • Element
    • Feedback
    • Protein
    • Function
    • Wcc
    • Codon
    • Drosophila
  • frq-less oscillator (flo)
    • Temperature
    • Although
    • Frq-less
    • Negative
    • Oscillator
    • Feedback
    • Protein
    • Structure
    • Mechanism
    • Also
    • Rhythms
    • Function

Connections between topic areas Semantic bridges

For Frequency (gene), one of the stronger structural bridges in this analysis connects Frequency (gene) with Regulation. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Frequency (gene) — Regulation · splits 49 ⟂ 17
Frequency (gene) — Discovery · splits 52 ⟂ 14
Frequency (gene) — Structure and function · splits 52 ⟂ 14
Frequency (gene) — Evolution · splits 58 ⟂ 8
Frequency (gene) — Overview · splits 59 ⟂ 7
Frequency (gene) — FRQ-less oscillator (FLO) · splits 61 ⟂ 5

Map overview Semantic statistics

Frequency (gene)

Nodes66
Edges65
Triples11
Avg. degree1.97
Density0.030303
Components1

Source & methodology

TTTA analyzes the structure around Frequency (gene) to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regulation, Discovery & Structure and function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Frequency (gene) · EN edition · Analysis: TopicsToTalkAbout

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