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Formins: Structure and interactions, Overview & Diversity

Formins (formin homology proteins) are a group of proteins that are involved in the polymerization of actin and associate with the fast-growing end (barbed end) of actin filaments. Most formins are Rho-GTPase effector proteins. Formins regulate the actin and microtubule cytoskeleton and are involved in various cellular functions such as cell polarity…

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Formins topic overview

The analysis highlights Structure and interactions, Overview and Diversity as prominent areas in the source structure around Formins.

Related topics
47
Source areas
3
Connected nodes
50
Extracted relationships
49
Concept neighborhoods
24
Bridge connections
50

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure and interactions · 29 topics
Overview · 16 topics
Diversity · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
LD, FMN
Domains
InterPro
HGNC
3768
Locus
Chr. 15 q13-q14
NCBI gene
342184
OMIM
136535

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Diversity

Structure and interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Formins connects Entity context

The extracted context around Formins shows recurring relationship patterns in the source. For example, Formins → Another, ARR, C-terminal, Cdc42, CRIB-like, DAD, Dia-autoregulatory, Drf3, FH, FH1, FH2, FH3, FHA, GBD, GTP-bound Rho, GTPase-binding, GTPases, In, Mammalian Drf3, N-terminal GBD Another extracted example is Formins → By, In. Use these groups to spot repeated connection types before inspecting the individual relationships.

Formins

Top relations

related to Structure and interactions · 32
Formins → Another, ARR, C-terminal, Cdc42, CRIB-like, DAD, Dia-autoregulatory, Drf3, FH, FH1, FH2, FH3, FHA, GBD, GTP-bound Rho, GTPase-binding, GTPases, In, Mammalian Drf3, N-terminal GBD
related to Diversity · 2
Formins → By, In
Alt. symbols · 1
Formins → LD, FMN
Domains · 1
Formins → InterPro
HGNC · 1
Formins → 3768
Locus · 1
Formins → Chr. 15 q13-q14
NCBI gene · 1
Formins → 342184
OMIM · 1
Formins → 136535
RefSeq · 1
Formins → NM_001103184
Search for · 1
Formins → Search forStructuresSwiss-modelDomainsInterPro

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin proteins domain formin domains microtubules fh2 also dad required gbd homology 15 involved functions q13-q14 polymerization srf contain fh3

Formins relationships Subject–Predicate–Object triples

TTTA extracted 49 structured relationships around Formins. Examples in this analysis include Formins → Alt. symbols → LD, FMN and Formins → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ForminsAlt. symbolsLD, FMN1.00infobox
ForminsDomainsInterPro1.00infobox
ForminsHGNC37681.00infobox
ForminsLocusChr. 15 q13-q141.00infobox
ForminsNCBI gene3421841.00infobox
ForminsOMIM1365351.00infobox
ForminsRefSeqNM_0011031841.00infobox
ForminsSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
ForminsStructuresSwiss-model1.00infobox
ForminsSymbolFMN11.00infobox
ForminsUniProtQ68DA71.00infobox
cell polarityinstance ofFormins regulate the actin and microtubule cytoskeleton and are involved in various cellular functions0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Formins bring nearby vocabulary together. In this analysis, examples include Actin, Contain and Domain. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Formins
    • Actin
    • Contain
    • Domain
    • Fh2
    • Proteins
    • Activity
    • Although
    • Cellular
    • Conserved
    • Filaments
    • Functions
    • Involved
  • formins
    • Actin
    • Contain
    • Domain
    • Fh2
    • Proteins
    • Activity
    • Although
    • Cellular
    • Conserved
    • Filaments
    • Functions
    • Involved
  • actin
    • Formin
    • Activity
    • Cell
    • Filaments
    • Formins
    • Involved
    • Mammalian
    • Polymerization
    • Srf
    • Also
    • Microtubules
    • Required
  • actin filament
    • Formin
    • Activity
    • Cell
    • Filaments
    • Formins
    • Involved
    • Mammalian
    • Polymerization
    • Srf
    • Also
    • Microtubules
    • Required
  • srf
    • Cytokinesis
    • Cytoskeleton
    • Microtubule
    • Activity
    • Cell
    • Cells
    • Cellular
    • Functions
    • Involved
    • Mammalian
    • Actin
    • Addition
  • ww domain
    • Fh2
    • Required
    • Formins
    • Conserved
    • Fh3
    • Rho
    • Gbd
    • Proteins
    • Binding
    • Interactions
    • Polymerization
    • Homology
  • cell polarity
    • Cytokinesis
    • Cytoskeleton
    • Microtubule
    • Activity
    • Binding
    • Cellular
    • Functions
    • Involved
    • Mammalian
    • Srf
    • Within
    • Gbd
  • cell migration
    • Cytokinesis
    • Cytoskeleton
    • Microtubule
    • Activity
    • Binding
    • Cellular
    • Functions
    • Involved
    • Mammalian
    • Srf
    • Within
    • Gbd

Connections between topic areas Semantic bridges

For Formins, one of the stronger structural bridges in this analysis connects Formins with Structure and interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ForminsStructure and interactions · splits 21 ⟂ 30
ForminsOverview · splits 34 ⟂ 17
ForminsDiversity · splits 48 ⟂ 3

Map overview Semantic statistics

Formins

Nodes51
Edges50
Triples49
Avg. degree1.96
Density0.039216
Components1

Source & methodology

TTTA analyzes the structure around Formins to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure and interactions, Overview & Diversity, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Formins · EN edition · Analysis: TopicsToTalkAbout

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