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Profilin: Allergen, Regulation of actin dynamics & Sources and distribution

Profilin is an actin-binding protein involved in the dynamic turnover and reconstruction of the actin cytoskeleton. It is found in most eukaryotic organisms. Profilin is important for spatially and temporally controlled growth of actin microfilaments, which is an essential process in cellular locomotion and cell shape changes. This restructuring of the…

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Profilin topic overview

The analysis highlights Allergen, Regulation of actin dynamics and Sources and distribution as prominent areas in the source structure around Profilin.

Related topics
77
Source areas
5
Connected nodes
82
Extracted relationships
56
Concept neighborhoods
23
Bridge connections
82

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Allergen · 29 topics
Overview · 16 topics
Regulation of actin dynamics · 16 topics
Sources and distribution · 11 topics
Human genes · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR002097 · PF00235
Available protein structures:
IPR002097 · PF00235
CDD
cd00148
InterPro
IPR002097
PDB
2btf​ IPR002097 PF00235 (ECOD; PDBsum)
Pfam
PF00235

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Sources and distribution

Regulation of actin dynamics

Allergen

Human genes

  • PFN1
  • PFN2
  • PFN3 PFN3?action=edit&redlink=1
  • PFN4 PFN4?action=edit&redlink=1
  • PFN5 PFN5?action=edit&redlink=1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Profilin connects Entity context

The extracted context around Profilin shows recurring relationship patterns in the source. For example, Profilin → ADP, ADP-actin, ATP, ATP-actin, FH1-domains, However, On, Profilin-actin, This, Thus, Vasodilator-stimulated, Wiskott-Aldrich Another extracted example is Profilin → After, As, Europe, How, Mercurialis, Spanish, Swedish. Use these groups to spot repeated connection types before inspecting the individual relationships.

Profilin

Top relations

related to Regulation of actin dynamics · 12
Profilin → ADP, ADP-actin, ATP, ATP-actin, FH1-domains, However, On, Profilin-actin, This, Thus, Vasodilator-stimulated, Wiskott-Aldrich
related to Allergen · 7
Profilin → After, As, Europe, How, Mercurialis, Spanish, Swedish
related to Sources and distribution · 6
Profilin → Asgard, II, In, Multiple, Profilins, They
is a · 4
Profilin → actin-binding protein involved in the dynamic turnover and reconstruction of the actin cytoskeleton, major allergen, major allergen of certain food plants, specific pathogen-associated molecular pattern
related to External links · 4
Profilin → Medicine Medical Subject Headings, MeSH, National Library, Profilins
related to history · 3
Profilin → It, Lars Carlsson, Uno Lindberg
AlphaFold · 2
Profilin → IPR002097, PF00235
Available protein structures: · 2
Profilin → IPR002097, PF00235
CDD · 1
Profilin → cd00148
InterPro · 1
Profilin → IPR002097

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin profilins proteins essential cell also protein monomers grass citation needed allergen cytoskeleton birch pollen allergy growth cells binds involved

Profilin relationships Subject–Predicate–Object triples

TTTA extracted 56 structured relationships around Profilin. Examples in this analysis include Profilin → AlphaFold → IPR002097 and Profilin → AlphaFold → PF00235. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ProfilinAlphaFoldIPR0020971.00infobox
ProfilinAlphaFoldPF002351.00infobox
ProfilinAvailable protein structures:IPR0020971.00infobox
ProfilinAvailable protein structures:PF002351.00infobox
ProfilinCDDcd001481.00infobox
ProfilinInterProIPR0020971.00infobox
ProfilinPDB2btf​ IPR002097 PF00235 (ECOD; PDBsum)1.00infobox
ProfilinPfamPF002351.00infobox
ProfilinPROSITEPS004141.00infobox
ProfilinSCOP22btf / SCOPe / SUPFAM1.00infobox
ProfilinSMARTPROF1.00infobox
ProfilinSymbolProfilin1.00infobox
Profilinis aactin-binding protein involved in the dynamic turnover and reconstruction of the actin cytoskeleton0.90text
Profilinis amajor allergen0.90text
Profilinis aspecific pathogen-associated molecular pattern0.90text
Profilinis amajor allergen of certain food plants0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Profilin bring nearby vocabulary together. In this analysis, examples include Actin, Monomers and Proteins. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Profilin
    • Actin
    • Monomers
    • Proteins
    • Allergy
    • Cell
    • Citation
    • Grass
    • Needed
    • Protein
    • Action
    • Binds
    • Birch
  • profilin
    • Actin
    • Monomers
    • Proteins
    • Allergy
    • Cell
    • Citation
    • Grass
    • Needed
    • Protein
    • Action
    • Binds
    • Birch
  • actin
    • Profilin
    • Protein
    • Proteins
    • Growth
    • Citation
    • Essential
    • Needed
    • Monomers
    • Binding
    • Cytoskeleton
    • Involved
    • Regulation
  • regulation of actin dynamics
    • Ige
    • Splicing
    • Profilin
    • Allergen
    • Genes
    • Major
    • Molecular
    • Present
    • Protein
    • Proteins
    • Birch
    • Pollen
  • allergen
    • Major
    • Ige
    • Genes
    • Molecular
    • Present
    • Regulation
    • Birch
    • Pollen
    • Allergy
    • Citation
    • Grass
    • Needed
  • birch
    • Grass
    • Pollen
    • Ige
    • Profilins
    • Development
    • Genes
    • Major
    • Molecular
    • Present
    • Regulation
    • Allergy
    • Citation
  • ige
    • Genes
    • Major
    • Molecular
    • Present
    • Regulation
    • Birch
    • Pollen
    • Citation
    • Grass
    • Needed
    • Protein
    • Profilins
  • human genes
    • Present
    • Ige
    • Major
    • Many
    • Molecular
    • Organisms
    • Regulation
    • Pollen
    • Grass
    • Needed
    • Protein
    • Profilins

Connections between topic areas Semantic bridges

For Profilin, one of the stronger structural bridges in this analysis connects Profilin with Allergen. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ProfilinAllergen · splits 53 ⟂ 30
ProfilinOverview · splits 66 ⟂ 17
ProfilinRegulation of actin dynamics · splits 66 ⟂ 17
ProfilinSources and distribution · splits 71 ⟂ 12
ProfilinHuman genes · splits 77 ⟂ 6

Map overview Semantic statistics

Profilin

Nodes83
Edges82
Triples56
Avg. degree1.98
Density0.024096
Components1

Source & methodology

TTTA analyzes the structure around Profilin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Allergen, Regulation of actin dynamics & Sources and distribution, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Profilin · EN edition · Analysis: TopicsToTalkAbout

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