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FKBP5

FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene.

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5.2.1.8
Aliases
FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10, FK506 binding protein 5, FKBP prolyl isomerase 5
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KT0, 3O5D, 3O5E, 3O5F, 3O5G, 3O5I, 3O5J, 3O5K, 3O5L, 3O5M, 3O5O, 3O5P, 3O5Q, 3O5R, 4DRH, 4DRI, 4DRK, 4DRM,…
Band
6p21.31 · 17 A3.3|17 14.66 cM
Bgee
gastric mucosa · pericardium · Skeletal muscle tissue of biceps brachii · right lung · skin of hip
BioGPS
More reference expression data

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Overview

Function

Structure

Clinical significance

FKBP51 Ligands

Interactions

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Map overview Semantic statistics

FKBP5

Nodes30
Edges29
Triples126
Avg. degree1.93
Density0.066667
Components1

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FKBP5

Top relations

Bgee · 20
FKBP5 → corpus epididymis, gastric mucosa, gastrocnemius muscle, gastrula, Gonadal ridge, lacrimal gland, left uterine tube, muscle of thigh, pericardium, primary oocyte, right lung, secondary oocyte, seminal vesicula, Skeletal muscle tissue of biceps brachii, skin of hip, skin of thigh, stroma of bone marrow, synovial joint, thymus, zygote
RNA expression pattern · 20
FKBP5 → corpus epididymis, gastric mucosa, gastrocnemius muscle, gastrula, Gonadal ridge, lacrimal gland, left uterine tube, muscle of thigh, pericardium, primary oocyte, right lung, secondary oocyte, seminal vesicula, Skeletal muscle tissue of biceps brachii, skin of hip, skin of thigh, stroma of bone marrow, synovial joint, thymus, zygote
Gene ontology · 15
FKBP5 → chaperone-mediated protein folding, cytoplasm, cytosol, extracellular exosome, FK506 binding, heat shock protein binding, isomerase activity, membrane, nucleoplasm, nucleus, peptidyl-prolyl cis-trans isomerase activity, protein binding, protein folding, protein peptidyl-prolyl isomerization, response to bacterium
related to Structure · 14
FKBP5 → C-terminal, FK1, FK2, FKBP, FKBP-like, FKBP-type, Hsp90, In, Instead, It, PPIase, The FK1, The TPR, TPR
related to Function · 9
FKBP5 → As, FK506, FKBP51, Hsp90-associated, It, P23, PTGES3, The, This
related to AKT phosphorylation · 6
FKBP5 → AKT, FK1, PHLPP, Ser473, TPR, Without FKBP51
related to Steroid hormone regulation · 6
FKBP5 → AR, GR, In, Interestingly, PR, These
related to FKBP51 Ligands · 4
FKBP5 → As, FKBP51, Macrocyclic FKBP51-selective, SAFit2
see also · 3
FKBP5 → DNA, FKBP, FKBP4
Band · 2
FKBP5 → 17 A3.3|17 14.66 cM, 6p21.31

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Important terminology

protein gene bp fkbp51 activity chr human band binding fk506 chromosome akt isomerase also ppiase location function receptors domain fk1

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FKBP55.2.1.81.00infobox
FKBP5AliasesFKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10, FK506 binding protein 5, FKBP prolyl isomerase 51.00infobox
FKBP5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KT0, 3O5D, 3O5E, 3O5F, 3O5G, 3O5I, 3O5J, 3O5K, 3O5L, 3O5M, 3O5O, 3O5P, 3O5Q, 3O5R, 4DRH, 4DRI, 4DRK, 4DRM,…1.00infobox
FKBP5Band6p21.311.00infobox
FKBP5Band17 A3.3|17 14.66 cM1.00infobox
FKBP5Bgeegastric mucosa1.00infobox
FKBP5Bgeepericardium1.00infobox
FKBP5BgeeSkeletal muscle tissue of biceps brachii1.00infobox
FKBP5Bgeeright lung1.00infobox
FKBP5Bgeeskin of hip1.00infobox
FKBP5Bgeeskin of thigh1.00infobox
FKBP5Bgeegastrocnemius muscle1.00infobox
FKBP5Bgeeleft uterine tube1.00infobox
FKBP5Bgeecorpus epididymis1.00infobox
FKBP5Bgeesynovial joint1.00infobox
FKBP5Bgeestroma of bone marrow1.00infobox
FKBP5Bgeelacrimal gland1.00infobox
FKBP5Bgeemuscle of thigh1.00infobox
FKBP5Bgeesecondary oocyte1.00infobox
FKBP5Bgeethymus1.00infobox
FKBP5Bgeegastrula1.00infobox
FKBP5Bgeezygote1.00infobox
FKBP5Bgeeprimary oocyte1.00infobox
FKBP5BgeeGonadal ridge1.00infobox
FKBP5Bgeeseminal vesicula1.00infobox
FKBP5BioGPSMore reference expression data1.00infobox
FKBP5Chr.Chromosome 6 (human)1.00infobox
FKBP5Chr.Chromosome 17 (mouse)1.00infobox
FKBP5DatabasesNCBI: entry; OMA: entry1.00infobox
FKBP5End35,728,583 bp1.00infobox

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