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FKBP3: Interactions, Function & Overview

FK506-binding protein 3 also known as FKBP25 is a protein that in humans is encoded by the FKBP3 gene.

Language: English [EN]
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FKBP3 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around FKBP3.

Related topics
12
Source areas
3
Connected nodes
15
Extracted relationships
90
Concept neighborhoods
8
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Function · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

5.2.1.8
Aliases
FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FK506 binding protein 3, FKBP prolyl isomerase 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PBK, 2KFV, 2MPH, 5D75
Band
14q21.2 · 12|12 C1
Bgee
Skeletal muscle tissue of biceps brachii · vastus lateralis muscle · Skeletal muscle tissue of rectus abdominis · Brodmann area 23 · body of tongue
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FKBP3 connects Entity context

The extracted context around FKBP3 shows recurring relationship patterns in the source. For example, FKBP3 → body of tongue, Brodmann area 23, deep cerebellar nuclei, dorsomedial hypothalamic nucleus, gastrocnemius muscle, intercostal muscle, lateral hypothalamus, lateral septal nucleus, mammillary body, medial vestibular nucleus, muscle of thigh, paraventricular nucleus of hypothalamus, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sperm, tail of embryo, thoracic diaphragm, vastus lateralis muscle, ventromedial nucleus Another extracted example is FKBP3 → chaperone-mediated protein folding, cytoplasm, FK506 binding, isomerase activity, nucleus, peptidyl-prolyl cis-trans isomerase activity, protein binding, protein peptidyl-prolyl isomerization, RNA binding, signaling receptor activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

FKBP3

Top relations

Bgee · 20
FKBP3 → body of tongue, Brodmann area 23, deep cerebellar nuclei, dorsomedial hypothalamic nucleus, gastrocnemius muscle, intercostal muscle, lateral hypothalamus, lateral septal nucleus, mammillary body, medial vestibular nucleus, muscle of thigh, paraventricular nucleus of hypothalamus, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sperm, tail of embryo, thoracic diaphragm, vastus lateralis muscle, ventromedial nucleus
RNA expression pattern · 20
FKBP3 → body of tongue, Brodmann area 23, deep cerebellar nuclei, dorsomedial hypothalamic nucleus, gastrocnemius muscle, intercostal muscle, lateral hypothalamus, lateral septal nucleus, mammillary body, medial vestibular nucleus, muscle of thigh, paraventricular nucleus of hypothalamus, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sperm, tail of embryo, thoracic diaphragm, vastus lateralis muscle, ventromedial nucleus
Gene ontology · 10
FKBP3 → chaperone-mediated protein folding, cytoplasm, FK506 binding, isomerase activity, nucleus, peptidyl-prolyl cis-trans isomerase activity, protein binding, protein peptidyl-prolyl isomerization, RNA binding, signaling receptor activity
related to Interactions · 10
FKBP3 → Both, DNA, FK506, FKBP25, HDAC1, Histone, Mdm2, NMR, PDB ID, YY1
related to External links · 5
FKBP3 → FKBP3PDBe-KB, Human Peptidyl-prolyl, Mouse Peptidyl-prolyl, PDB, PDBe-KB
Band · 2
FKBP3 → 12|12 C1, 14q21.2
Chr. · 2
FKBP3 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
FKBP3 → 45,135,319 bp, 65,120,781 bp
5.2.1.8 · 1
FKBP3 → ↗
Aliases · 1
FKBP3 → FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FK506 binding protein 3, FKBP prolyl isomerase 3

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human gene chr protein band fk506 chromosome 14 isomerase mouse fkbp25 location encoded pdb cis-trans function external binding search

FKBP3 relationships Subject–Predicate–Object triples

TTTA extracted 90 structured relationships around FKBP3. Examples in this analysis include FKBP3 → 5.2.1.8 → ↗ and FKBP3 → Aliases → FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FK506 binding protein 3, FKBP prolyl isomerase 3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FKBP35.2.1.81.00infobox
FKBP3AliasesFKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FK506 binding protein 3, FKBP prolyl isomerase 31.00infobox
FKBP3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PBK, 2KFV, 2MPH, 5D751.00infobox
FKBP3Band14q21.21.00infobox
FKBP3Band12|12 C11.00infobox
FKBP3BgeeSkeletal muscle tissue of biceps brachii1.00infobox
FKBP3Bgeevastus lateralis muscle1.00infobox
FKBP3BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
FKBP3BgeeBrodmann area 231.00infobox
FKBP3Bgeebody of tongue1.00infobox
FKBP3Bgeemuscle of thigh1.00infobox
FKBP3Bgeegastrocnemius muscle1.00infobox
FKBP3Bgeesperm1.00infobox
FKBP3Bgeethoracic diaphragm1.00infobox
FKBP3Bgeeright ventricle1.00infobox
FKBP3Bgeemedial vestibular nucleus1.00infobox
FKBP3Bgeemammillary body1.00infobox
FKBP3Bgeelateral hypothalamus1.00infobox
FKBP3Bgeeintercostal muscle1.00infobox
FKBP3Bgeeventromedial nucleus1.00infobox
FKBP3Bgeetail of embryo1.00infobox
FKBP3Bgeedeep cerebellar nuclei1.00infobox
FKBP3Bgeelateral septal nucleus1.00infobox
FKBP3Bgeedorsomedial hypothalamic nucleus1.00infobox
FKBP3Bgeeparaventricular nucleus of hypothalamus1.00infobox
FKBP3BioGPSMore reference expression data1.00infobox
FKBP3Chr.Chromosome 14 (human)1.00infobox
FKBP3Chr.Chromosome 12 (mouse)1.00infobox
FKBP3DatabasesNCBI: entry; OMA: entry1.00infobox
FKBP3End45,135,319 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around FKBP3 bring nearby vocabulary together. In this analysis, examples include Gene, Isomerase and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • FKBP3
    • Gene
    • Isomerase
    • Protein
    • Human
    • Activity
    • Available
    • Binding
    • Function
    • Peptidyl-prolyl
    • Search
    • Cis-trans
    • Location
  • fkbp3
    • Gene
    • Isomerase
    • Protein
    • Human
    • Activity
    • Available
    • Binding
    • Function
    • Peptidyl-prolyl
    • Search
    • Cis-trans
    • Location
  • gene
    • Location
    • Chromosome
    • Protein
    • Activity
    • Binding
    • Bp
    • Chr
    • End
    • Function
    • Human
    • Search
    • Mouse
  • function
    • Activity
    • Search
    • Location
    • Cellular
    • Chromosome
    • Folding
    • Gene
    • Isomerase
    • Protein
    • Bp
    • Chr
    • Human
  • cis-trans prolyl isomerase
    • Cis-trans
    • Isomerase
    • Peptidyl-prolyl
    • Protein
    • Encoded
    • Human
    • Mouse
    • Prolyl
    • Search
    • Location
    • Pdb
    • Fk506
  • protein folding
    • Function
    • Peptidyl-prolyl
    • Search
    • Cis-trans
    • Location
    • Mouse
    • Human
    • Cellular
    • Folding
    • Gene
    • Isomerase
    • Protein
  • protein
    • Search
    • Cis-trans
    • Location
    • Human
    • Cellular
    • Folding
    • End
    • Id
    • Peptidyl-prolyl
    • Rapamycin
    • Mouse
    • Pdb
  • rapamycin
    • Fk506
    • Prolyl
    • Cis-trans
    • Encoded
    • Isomerase
    • Protein

Connections between topic areas Semantic bridges

For FKBP3, one of the stronger structural bridges in this analysis connects FKBP3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FKBP3Interactions · splits 9 ⟂ 7
FKBP3Function · splits 11 ⟂ 5
FKBP3Overview · splits 13 ⟂ 3

Map overview Semantic statistics

FKBP3

Nodes16
Edges15
Triples90
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around FKBP3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FKBP3 · EN edition · Analysis: TopicsToTalkAbout

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