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FK1012

FK1012 is a dimer consisting of two molecules of tacrolimus (FK506) linked via their vinyl groups. It is used as a research tool in chemically induced dimerization applications. FK1012 is a chemical inducer of dimerization (CID) which makes the protein capable of dimerization or oligomerization of fusion proteins containing one or more FKBP12 domains. It…

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FK1012

Nodes8
Edges7
Triples2
Avg. degree1.75
Density0.25
Components1

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FK1012

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is a · 2
FK1012 → chemical inducer of dimerization, dimer consisting of two molecules of tacrolimus

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Important terminology

fk506 used proteins dimer dimerization protein fkbps chemical cid references standard state 10 97 tacrolimus vinyl blood 11 3662 consisting

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FK1012is adimer consisting of two molecules of tacrolimus0.90text
FK1012is achemical inducer of dimerization0.90text

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