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FANCL

E3 ubiquitin-protein ligase FANCL is an enzyme that in humans is encoded by the FANCL gene.

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2.3.2.27
Aliases
FANCL, FAAP43, PHF9, POG, Fanconi anemia complementation group L, FA complementation group L
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ZQS, 4CCG
Band
2p16.1 · 11|11 A3.3
Bgee
pituitary gland · anterior pituitary · Achilles tendon · right adrenal cortex · corpus callosum
BioGPS
More reference expression data

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Function

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Map overview Semantic statistics

FANCL

Nodes38
Edges37
Triples107
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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FANCL

Top relations

related to Structure · 21
FANCL → Activated FANCD2, BRCA1, DNA, E2, ELF, FA, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCM, ICL, In, N-terminal E2-like, RING, RING E3, The ELF
Bgee · 20
FANCL → abdominal wall, Achilles tendon, anterior pituitary, C1 segment, corpus callosum, endocardial cushion, epiblast, fetal liver hematopoietic progenitor cell, fossa, interventricular septum, left adrenal cortex, mandibular prominence, maxillary prominence, Paneth cell, pituitary gland, primitive streak, right adrenal cortex, right uterine tube, secondary oocyte, tibia
Gene ontology · 20
FANCL → cellular response to DNA damage stimulus, cytoplasm, DNA repair, Fanconi anaemia nuclear complex, gamete generation, interstrand cross-link repair, intracellular membrane-bounded organelle, metal ion binding, nuclear body, nuclear envelope, nucleoplasm, nucleus, protein binding, protein monoubiquitination, protein ubiquitination, regulation of cell population proliferation, transferase activity, ubiquitin protein ligase activity, ubiquitin protein ligase binding, ubiquitin-protein transferase activity
RNA expression pattern · 20
FANCL → abdominal wall, Achilles tendon, anterior pituitary, C1 segment, corpus callosum, endocardial cushion, epiblast, fetal liver hematopoietic progenitor cell, fossa, interventricular septum, left adrenal cortex, mandibular prominence, maxillary prominence, Paneth cell, pituitary gland, primitive streak, right adrenal cortex, right uterine tube, secondary oocyte, tibia
Band · 2
FANCL → 11|11 A3.3, 2p16.1
Chr. · 2
FANCL → Chromosome 11 (mouse), Chromosome 2 (human)
End · 2
FANCL → 26,421,876 bp, 58,241,410 bp
2.3.2.27 · 1
FANCL → ↗
Aliases · 1
FANCL → FANCL, FAAP43, PHF9, POG, Fanconi anemia complementation group L, FA complementation group L
Available structures · 1
FANCL → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ZQS, 4CCG

Important terminology Word statistics

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Important terminology

dna fancd2 bp gene chr human band fa complex brca1 rad51 fanconi chromosome anemia protein damage ligase location function ubiquitin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FANCL2.3.2.271.00infobox
FANCLAliasesFANCL, FAAP43, PHF9, POG, Fanconi anemia complementation group L, FA complementation group L1.00infobox
FANCLAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ZQS, 4CCG1.00infobox
FANCLBand2p16.11.00infobox
FANCLBand11|11 A3.31.00infobox
FANCLBgeepituitary gland1.00infobox
FANCLBgeeanterior pituitary1.00infobox
FANCLBgeeAchilles tendon1.00infobox
FANCLBgeeright adrenal cortex1.00infobox
FANCLBgeecorpus callosum1.00infobox
FANCLBgeeleft adrenal cortex1.00infobox
FANCLBgeeC1 segment1.00infobox
FANCLBgeetibia1.00infobox
FANCLBgeesecondary oocyte1.00infobox
FANCLBgeeright uterine tube1.00infobox
FANCLBgeePaneth cell1.00infobox
FANCLBgeeprimitive streak1.00infobox
FANCLBgeeabdominal wall1.00infobox
FANCLBgeemandibular prominence1.00infobox
FANCLBgeefetal liver hematopoietic progenitor cell1.00infobox
FANCLBgeeepiblast1.00infobox
FANCLBgeeendocardial cushion1.00infobox
FANCLBgeemaxillary prominence1.00infobox
FANCLBgeeinterventricular septum1.00infobox
FANCLBgeefossa1.00infobox
FANCLBioGPSMore reference expression data1.00infobox
FANCLChr.Chromosome 2 (human)1.00infobox
FANCLChr.Chromosome 11 (mouse)1.00infobox
FANCLDatabasesNCBI: entry; OMA: entry1.00infobox
FANCLEnd58,241,410 bp1.00infobox

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