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Fanconi anemia, complementation group M, also known as FANCM, is a human gene. It is an emerging target in cancer therapy, in particular cancers with specific genetic deficiencies.
The analysis highlights Art, Function and Clinical significance as prominent areas in the source structure around FANCM.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FANCM shows recurring relationship patterns in the source. For example, FANCM → 3'-5' DNA helicase activity, ATP binding, cellular response to DNA damage stimulus, chromatin binding, DNA binding, DNA duplex unwinding, DNA repair, FANCM-MHF complex, Fanconi anaemia nuclear complex, helicase activity, hydrolase activity, interstrand cross-link repair, nuclease activity, nucleic acid phosphodiester bond hydrolysis, nucleoplasm, nucleotide binding, nucleus, positive regulation of protein monoubiquitination, protein binding, replication fork processing Another extracted example is FANCM → ALT, ALT-associated, ALT-cells, Alternative Lengthening, An, As, Bloom Syndrome, DNA, Ectopic MM2, Expression, In, MM2, MM2-RMI1, PIP-199, RMI1, RMI2, Several, Telomeres, There, This. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna human gene recombination bp protein chr band also activity fanconi chromosome co cancer 14 helicase nco meiosis complex anemia
TTTA extracted 134 structured relationships around FANCM. Examples in this analysis include FANCM → 3.6.4.13 → ↗ and FANCM → Aliases → FANCM, FAAP250, KIAA1596, Fanconi anemia complementation group M, FA complementation group M, POF15, SPGF28. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FANCM | 3.6.4.13 | ↗ | 1.00 | infobox |
| FANCM | Aliases | FANCM, FAAP250, KIAA1596, Fanconi anemia complementation group M, FA complementation group M, POF15, SPGF28 | 1.00 | infobox |
| FANCM | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4BXO, 4DAY, 4DRB, 4E45, 4M6W | 1.00 | infobox |
| FANCM | Band | 14q21.2 | 1.00 | infobox |
| FANCM | Band | 12 C1|12 27.21 cM | 1.00 | infobox |
| FANCM | Bgee | sperm | 1.00 | infobox |
| FANCM | Bgee | oocyte | 1.00 | infobox |
| FANCM | Bgee | testicle | 1.00 | infobox |
| FANCM | Bgee | secondary oocyte | 1.00 | infobox |
| FANCM | Bgee | ventricular zone | 1.00 | infobox |
| FANCM | Bgee | gonad | 1.00 | infobox |
| FANCM | Bgee | right testis | 1.00 | infobox |
| FANCM | Bgee | left testis | 1.00 | infobox |
| FANCM | Bgee | Achilles tendon | 1.00 | infobox |
| FANCM | Bgee | ganglionic eminence | 1.00 | infobox |
| FANCM | Bgee | tail of embryo | 1.00 | infobox |
| FANCM | Bgee | blastocyst | 1.00 | infobox |
| FANCM | Bgee | genital tubercle | 1.00 | infobox |
| FANCM | Bgee | morula | 1.00 | infobox |
| FANCM | Bgee | zygote | 1.00 | infobox |
| FANCM | Bgee | epiblast | 1.00 | infobox |
| FANCM | Bgee | spermatocyte | 1.00 | infobox |
| FANCM | BioGPS | n/a | 1.00 | infobox |
| FANCM | Chr. | Chromosome 14 (human) | 1.00 | infobox |
| FANCM | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| FANCM | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FANCM | End | 45,200,890 bp | 1.00 | infobox |
| FANCM | End | 65,178,832 bp | 1.00 | infobox |
| FANCM | Ensembl | ENSG00000187790 | 1.00 | infobox |
| FANCM | Entrez | 57697 | 1.00 | infobox |
The concept neighborhoods around FANCM bring nearby vocabulary together. In this analysis, examples include Fanconi, Helicase and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FANCM, one of the stronger structural bridges in this analysis connects FANCM with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FANCM to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FANCM · EN edition · Analysis: TopicsToTalkAbout