ICAM3

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ICAM3 topic overview

The analysis highlights Art, Function and Interactions as prominent areas in the source structure around ICAM3.

Related topics: 27
Source areas: 4
Connected nodes: 31
Extracted relationships: 82
Concept neighborhoods: 23
Bridge connections: 31

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 10 topics

Overview · 8 topics

Interactions · 5 topics

Protein structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ICAM3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3
Available structures: Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1T0P
Band: 19p13.2
Bgee: blood · granulocyte · monocyte · bone marrow cell · trabecular bone
BioGPS: More reference expression data
Chr.: Chromosome 19 (human)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Interactions

LFA-1 Lymphocyte function-associated antigen 1
Interact Protein-protein interaction
ERM proteins ERM protein family
Ezrin
Moesin

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ICAM3 connects Entity context

The extracted context around ICAM3 shows recurring relationship patterns in the source. For example, ICAM3 → cell adhesion, cell-cell adhesion, extracellular exosome, extracellular matrix organization, integral component of membrane, integral component of plasma membrane, integrin binding, membrane, phagocytosis, plasma membrane, protein binding, regulation of immune response, signaling receptor binding, stimulatory C-type lectin receptor signaling pathway Another extracted example is ICAM3 → appendix, blood, bone marrow cell, granulocyte, lymph node, monocyte, periodontal fiber, right lobe of liver, spleen, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 14

ICAM3 → cell adhesion, cell-cell adhesion, extracellular exosome, extracellular matrix organization, integral component of membrane, integral component of plasma membrane, integrin binding, membrane, phagocytosis, plasma membrane, protein binding, regulation of immune response, signaling receptor binding, stimulatory C-type lectin receptor signaling pathway

Bgee · 10

ICAM3 → appendix, blood, bone marrow cell, granulocyte, lymph node, monocyte, periodontal fiber, right lobe of liver, spleen, trabecular bone

RNA expression pattern · 10

ICAM3 → appendix, blood, bone marrow cell, granulocyte, lymph node, monocyte, periodontal fiber, right lobe of liver, spleen, trabecular bone

related to Dendritic and T cell binding · 6

ICAM3 → Binding, DC-SIGN, MHC, Resting, TCR, This

related to External links · 6

ICAM3 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library

related to Apoptosis · 5

ICAM3 → Apoptotic, CD14, Interactions, These, This

related to Additional interactions · 2

ICAM3 → ERM, EZR

related to Integrins · 2

ICAM3 → LFA-1, To

related to Mast cells · 2

ICAM3 → HMC-1, Mast

related to Protein structure · 2

ICAM3 → ICAM, Like

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells also binding cell adhesion protein integrin interactions dendritic expressed macrophages human surface apoptotic phagocytosis immune gene receptor process bp

ICAM3 relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around ICAM3. Examples in this analysis include ICAM3 → Aliases → ICAM3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3 and ICAM3 → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1T0P. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
ICAM3	Aliases	ICAM3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3	1.00	infobox
ICAM3	Available structures	Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1T0P	1.00	infobox
ICAM3	Band	19p13.2	1.00	infobox
ICAM3	Bgee	blood	1.00	infobox
ICAM3	Bgee	granulocyte	1.00	infobox
ICAM3	Bgee	monocyte	1.00	infobox
ICAM3	Bgee	bone marrow cell	1.00	infobox
ICAM3	Bgee	trabecular bone	1.00	infobox
ICAM3	Bgee	periodontal fiber	1.00	infobox
ICAM3	Bgee	spleen	1.00	infobox
ICAM3	Bgee	lymph node	1.00	infobox
ICAM3	Bgee	right lobe of liver	1.00	infobox
ICAM3	Bgee	appendix	1.00	infobox
ICAM3	BioGPS	More reference expression data	1.00	infobox
ICAM3	Chr.	Chromosome 19 (human)	1.00	infobox
ICAM3	Databases	NCBI: entry; OMA: entry	1.00	infobox
ICAM3	End	10,339,661 bp	1.00	infobox
ICAM3	Ensembl	ENSG00000076662	1.00	infobox
ICAM3	Entrez	3385	1.00	infobox
ICAM3	External IDs	OMIM: 146631; GeneCards: ICAM3	1.00	infobox
ICAM3	Gene location (Human)	Gene location (Human)Chr.Chromosome 19 (human)Band19p13.2Start10,333,776 bpEnd10,339,661 bp	1.00	infobox
ICAM3	Gene ontology	integrin binding	1.00	infobox
ICAM3	Gene ontology	signaling receptor binding	1.00	infobox
ICAM3	Gene ontology	protein binding	1.00	infobox
ICAM3	Gene ontology	integral component of membrane	1.00	infobox
ICAM3	Gene ontology	plasma membrane	1.00	infobox
ICAM3	Gene ontology	integral component of plasma membrane	1.00	infobox
ICAM3	Gene ontology	extracellular exosome	1.00	infobox
ICAM3	Gene ontology	membrane	1.00	infobox
ICAM3	Gene ontology	cell adhesion	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ICAM3 bring nearby vocabulary together. In this analysis, examples include Cells, Also and Binding. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

ICAM3
- Cells
- Also
- Binding
- Cell
- Integrin
- Apoptotic
- Expressed
- Interactions
- Extracellular
- Gene
- Mast
- Phagocytosis
icam3
- Cells
- Also
- Binding
- Cell
- Integrin
- Apoptotic
- Expressed
- Interactions
- Extracellular
- Gene
- Mast
- Phagocytosis
gene
- Intercellular
- Molecule
- Protein
- Uniprot
- Bp
- Chr
- Chromosome
- Function
- Human
- Expressed
- Binding
- Cell
t cells
- Icam3
- Apoptotic
- Interactions
- Cell
- Dendritic
- Mast
- Macrophages
- Binding
- Apoptosis
- Immune
- Phagocytosis
- Proteins
dendritic cells
- Icam3
- Interactions
- Apoptotic
- Function
- Response
- Cell
- Immune
- Dendritic
- Receptor
- Mast
- Macrophages
- Binding
apoptosis
- Phagocytosis
- Cell
- Macrophages
- Apoptotic
- Mediates
- Uniprot
- Binding
- Bp
- Chr
- Chromosome
- Function
- Intercellular
intercellular adhesion molecule
- Molecule
- Gene
- Uniprot
- Protein
- Bp
- Chr
- Chromosome
- Function
- Intercellular
- Binding
- Human
- Integrin
t cell receptor
- Surface
- Dendritic
- Apoptosis
- Cd14
- Function
- Phagocytes
- Response
- Immune
- Phagocytosis
- Process
- Human
- Macrophages

Connections between topic areas Semantic bridges

For ICAM3, one of the stronger structural bridges in this analysis connects ICAM3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

ICAM3 — Function · splits 21 ⟂ 11

ICAM3 — Overview · splits 23 ⟂ 9

ICAM3 — Interactions · splits 26 ⟂ 6

ICAM3 — Protein structure · splits 27 ⟂ 5

Map overview Semantic statistics

ICAM3

Nodes32

Edges31

Triples82

Avg. degree1.94

Density0.0625

Components1

Source & methodology

TTTA analyzes the structure around ICAM3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ICAM3 · EN edition · Analysis: TopicsToTalkAbout