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Halothane: History, Community, Culture & Applications

Halothane (bromochlorotrifluoroethane), sold under the brand name Fluothane among others, is a halocarbon with the chemical formula CF3CHBrCl. It is used as a general anaesthetic given by inhalation. It can be used to induce or maintain anaesthesia. Its use in developed countries has been mostly replaced by newer anesthetic agents such as sevoflurane.…

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Halothane topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Halothane.

Related topics
79
Source areas
9
Connected nodes
88
Extracted relationships
94
Concept neighborhoods
22
Bridge connections
88

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 20 topics
Society and culture · 13 topics
History · 10 topics
Pharmacology · 10 topics
Side effects · 9 topics
Chemical and physical properties · 7 topics
Medical uses · 4 topics
Synthesis · 4 topics
Related substances · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
FDA Professional Drug Information
ATC code
N01AB01 (WHO)
Boiling point
50.2 °C (122.4 °F)
CAS Number
151-67-7 Y
ChEBI
CHEBI:5615 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Pharmacology

Chemical and physical properties

Synthesis

Related substances

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Halothane connects Entity context

The extracted context around Halothane shows recurring relationship patterns in the source. For example, Halothane → British, But, ICI Widnes Laboratory, Imperial Chemical Industries, In, Initially, It, Its, Johnstone, Manchester, National Health Service, Suckling, United States Another extracted example is Halothane → About, By, C-section, Concern, However, In, It, Side, Since, The, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Halothane

Top relations

related to history · 13
Halothane → British, But, ICI Widnes Laboratory, Imperial Chemical Industries, In, Initially, It, Its, Johnstone, Manchester, National Health Service, Suckling, United States
has effect · 11
Halothane → About, By, C-section, Concern, However, In, It, Side, Since, The, This
related to Occupational safety · 6
Halothane → Health, NIOSH, Occupational Safety, People, REL, The National Institute
related to Pharmacology · 6
Halothane → AMPA, GABAA, HT3, It, NMDA, The
related to Greenhouse gas · 4
Halothane → Despite, GWP, However, Owing
related to Related substances · 4
Halothane → Attempts, Isoflurane, Small, The
related to Chemical and physical properties · 3
Halothane → Chemically, It, The
related to Medical uses · 3
Halothane → It, Its, MAC
related to Ozone depletion · 3
Halothane → Montreal Protocol, ODP, Unlike
Legal status · 2
Halothane → BR: Class C1 (Other controlled substances), US: ℞-only

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

used agents use anesthetic volatile inhalation isoflurane sevoflurane many replaced anesthetics ozone liver hepatitis potent induction anaesthetic newer one united

Halothane relationships Subject–Predicate–Object triples

TTTA extracted 94 structured relationships around Halothane. Examples in this analysis include Halothane → 3D model (JSmol) → Interactive image and Halothane → AHFS/Drugs.com → FDA Professional Drug Information. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Halothane3D model (JSmol)Interactive image1.00infobox
HalothaneAHFS/Drugs.comFDA Professional Drug Information1.00infobox
HalothaneATC codeN01AB01 (WHO)1.00infobox
HalothaneBoiling point50.2 °C (122.4 °F)1.00infobox
HalothaneCAS Number151-67-7 Y1.00infobox
HalothaneChEBICHEBI:5615 Y1.00infobox
HalothaneChEMBLChEMBL931 Y1.00infobox
HalothaneChemSpider3441 Y1.00infobox
HalothaneCompTox Dashboard (EPA)DTXSID40253711.00infobox
HalothaneDensity1.871 g/cm3 (at 20 °C)1.00infobox
HalothaneDrug classVolatile anesthetic1.00infobox
HalothaneDrugBankDB01159 Y1.00infobox
HalothaneECHA InfoCard100.005.2701.00infobox
HalothaneExcretionKidney, respiratory1.00infobox
HalothaneFormulaC2HBrClF31.00infobox
HalothaneIUPHAR/BPS24011.00infobox
HalothaneKEGGD00542 Y1.00infobox
HalothaneLegal statusBR: Class C1 (Other controlled substances)1.00infobox
HalothaneLegal statusUS: ℞-only1.00infobox
HalothaneLicense dataUS DailyMed: Halothane1.00infobox
HalothaneMelting point−118 °C (−180 °F)1.00infobox
HalothaneMetabolismHepatic (CYP2E1)1.00infobox
HalothaneMolar mass197.38 g·mol−11.00infobox
HalothanePubChem CID35621.00infobox
HalothaneRoutes of administrationInhalation1.00infobox
HalothaneTrade namesFluothane, Somnothane, Rhodialothan1.00infobox
HalothaneUNIIUQT9G45D1P1.00infobox
Halothaneis achiral molecule that is used as a racemic mixture.Halothane was discovered in 19510.90text
Halothaneis aalkyl halide0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Halothane bring nearby vocabulary together. In this analysis, examples include Depletion, Gas and Hepatitis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Halothane
    • Depletion
    • Gas
    • Hepatitis
    • Liver
    • Metabolism
    • Ozone
    • Inhalation
    • Many
    • Volatile
    • People
    • Induction
    • Isoflurane
  • halothane
    • Depletion
    • Gas
    • Hepatitis
    • Liver
    • Metabolism
    • Ozone
    • Inhalation
    • Many
    • Volatile
    • People
    • Induction
    • Isoflurane
  • volatile anesthetics
    • Anesthetics
    • Volatile
    • Like
    • Isoflurane
    • Anesthetic
    • Used
    • General
    • People
    • Substances
    • Chemical
    • Depletion
    • Developed
  • inhalational anesthetic
    • Countries
    • Developed
    • Newer
    • Sevoflurane
    • Replaced
    • Volatile
    • Use
    • Agents
    • Substances
    • Chemical
    • Depletion
    • Effects
  • inhalation
    • Induction
    • Used
    • Substances
    • Depletion
    • Effects
    • Respiratory
    • Side
    • Gas
    • Hepatitis
    • Lower
    • Metabolism
    • Ozone
  • chemical formula
    • Substances
    • Depletion
    • Effects
    • Respiratory
    • Side
    • Gas
    • Metabolism
    • Ozone
    • Inhalation
    • Potent
    • Anesthetic
    • Volatile
  • imperial chemical industries
    • Substances
    • Depletion
    • Effects
    • Respiratory
    • Side
    • Gas
    • Metabolism
    • Ozone
    • Inhalation
    • Potent
    • Anesthetic
    • Volatile
  • chemical and physical properties
    • Substances
    • Depletion
    • Effects
    • Respiratory
    • Side
    • Gas
    • Metabolism
    • Ozone
    • Inhalation
    • Potent
    • Anesthetic
    • Volatile

Connections between topic areas Semantic bridges

For Halothane, one of the stronger structural bridges in this analysis connects Halothane with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HalothaneOverview · splits 68 ⟂ 21
HalothaneSociety and culture · splits 75 ⟂ 14
HalothanePharmacology · splits 78 ⟂ 11
HalothaneHistory · splits 78 ⟂ 11
HalothaneSide effects · splits 79 ⟂ 10
HalothaneChemical and physical properties · splits 81 ⟂ 8
HalothaneMedical uses · splits 84 ⟂ 5
HalothaneSynthesis · splits 84 ⟂ 5
HalothaneRelated substances · splits 86 ⟂ 3

Map overview Semantic statistics

Halothane

Nodes89
Edges88
Triples94
Avg. degree1.98
Density0.022472
Components1

Source & methodology

TTTA analyzes the structure around Halothane to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Halothane · EN edition · Analysis: TopicsToTalkAbout

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