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Dedicator of cytokinesis protein 1 (Dock1), also (DOCK180), is a large (~180 kDa) protein encoded in the human by the DOCK1 gene, involved in intracellular signalling networks. It is the mammalian ortholog of the C. elegans protein CED-5 and belongs to the DOCK family of guanine nucleotide exchange factors (GEFs).
Structure and function, Regulation of DOCK180 Activity & Signalling Downstream of DOCK180
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dock180 protein human bp chr band proteins signalling dock1 exchange gene chromosome 10 domain binding small involved crk elmo activity
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Dedicator of cytokinesis protein 1 | Aliases | DOCK1, DOCK180, ced5, Dock180, dedicator of cytokinesis 1 | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3L4C | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Band | 10q26.2 | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Band | 7|7 F3 | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | corpus callosum | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | internal globus pallidus | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | olfactory bulb | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | sural nerve | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | Achilles tendon | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | C1 segment | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | amygdala | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | subthalamic nucleus | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | Paneth cell | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | molar | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | vas deferens | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | mandibular prominence | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | ureter | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | stria vascularis | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | maxillary prominence | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Bgee | adrenal gland | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | BioGPS | n/a | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | End | 127,452,517 bp | 1.00 | infobox |
| Dedicator of cytokinesis protein 1 | End | 134,775,368 bp | 1.00 | infobox |
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