DNAJA3

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DNAJA3 topic overview

The analysis highlights Clinical significance, Function and Structure as prominent areas in the source structure around DNAJA3.

Related topics: 61
Source areas: 5
Connected nodes: 66
Extracted relationships: 165
Concept neighborhoods: 18
Bridge connections: 66

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 20 topics

Function · 18 topics

Overview · 12 topics

Structure · 6 topics

Interactions · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: DNAJA3, HCA57, TID1, hTID-1, DnaJ heat shock protein family (Hsp40) member A3
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CTT, 2DN9
Band: 16p13.3 · 16 A1|16 2.46 cM
Bgee: gastrocnemius muscle · skeletal muscle tissue · muscle of thigh · right adrenal gland · right adrenal cortex
BioGPS: More reference expression data
Chr.: Chromosome 16 (human) · Chromosome 16 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Interact Protein-protein interaction
ErbB-2 receptor
HSPA8
JAK2 Janus kinase 2
RASA1 RAS p21 protein activator 1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DNAJA3 connects Entity context

The extracted context around DNAJA3 shows recurring relationship patterns in the source. For example, DNAJA3 → actin filament, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation-induced cell death of T cells, apoptotic process, ATP binding, cell junction, cytoplasm, cytosol, extrinsic component of plasma membrane, GTPase regulator activity, heat shock protein binding, Hsp70 protein binding, I-kappaB/NF-kappaB complex, IkappaB kinase complex, interferon-gamma receptor binding, intracellular membrane-bounded organelle, membrane, metal ion binding, mitochondrial DNA replication, mitochondrial matrix Another extracted example is DNAJA3 → apex of heart, brown adipose tissue, digastric muscle, extensor digitorum longus muscle, gastrocnemius muscle, Ileal epithelium, interventricular septum, left adrenal cortex, left adrenal gland, left ventricle, muscle of thigh, myocardium of ventricle, plantaris muscle, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 54

DNAJA3 → actin filament, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation-induced cell death of T cells, apoptotic process, ATP binding, cell junction, cytoplasm, cytosol, extrinsic component of plasma membrane, GTPase regulator activity, heat shock protein binding, Hsp70 protein binding, I-kappaB/NF-kappaB complex, IkappaB kinase complex, interferon-gamma receptor binding, intracellular membrane-bounded organelle, membrane, metal ion binding, mitochondrial DNA replication, mitochondrial matrix

Bgee · 20

DNAJA3 → apex of heart, brown adipose tissue, digastric muscle, extensor digitorum longus muscle, gastrocnemius muscle, Ileal epithelium, interventricular septum, left adrenal cortex, left adrenal gland, left ventricle, muscle of thigh, myocardium of ventricle, plantaris muscle, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle

RNA expression pattern · 20

related to Clinical significance · 16

DNAJA3 → Additionally, AKT, Another, EGFR, ErbB2, HNSCC, HSP27, In, It, MDM2, MK5, Moreover, Parkinson's, This, Thus, Under

related to Structure · 11

DNAJA3 → As, C-terminal, DnaJ, DNAJ/Hsp40, G/F, HPD, Hsp70, In, N-terminal, The, The DnaJ

related to Function · 10

DNAJA3 → ATPase, Before, DNAJ/Hsp40, DRP1, However, Hsp70, In, The, These, This

Band · 2

DNAJA3 → 16 A1|16 2.46 cM, 16p13.3

Chr. · 2

DNAJA3 → Chromosome 16 (human), Chromosome 16 (mouse)

End · 2

DNAJA3 → 4,456,775 bp, 4,525,559 bp

related to Interactions · 2

DNAJA3 → ErbB-2, JAK2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein mitochondrial dnaj bp chromosome 16 hsp70 cell chr human band membrane gene complex hsp40 function member family isoform also

DNAJA3 relationships Subject–Predicate–Object triples

TTTA extracted 165 structured relationships around DNAJA3. Examples in this analysis include DNAJA3 → Aliases → DNAJA3, HCA57, TID1, hTID-1, DnaJ heat shock protein family (Hsp40) member A3 and DNAJA3 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CTT, 2DN9. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
DNAJA3	Aliases	DNAJA3, HCA57, TID1, hTID-1, DnaJ heat shock protein family (Hsp40) member A3	1.00	infobox
DNAJA3	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CTT, 2DN9	1.00	infobox
DNAJA3	Band	16p13.3	1.00	infobox
DNAJA3	Band	16 A1\|16 2.46 cM	1.00	infobox
DNAJA3	Bgee	gastrocnemius muscle	1.00	infobox
DNAJA3	Bgee	skeletal muscle tissue	1.00	infobox
DNAJA3	Bgee	muscle of thigh	1.00	infobox
DNAJA3	Bgee	right adrenal gland	1.00	infobox
DNAJA3	Bgee	right adrenal cortex	1.00	infobox
DNAJA3	Bgee	right lobe of liver	1.00	infobox
DNAJA3	Bgee	left adrenal gland	1.00	infobox
DNAJA3	Bgee	left ventricle	1.00	infobox
DNAJA3	Bgee	left adrenal cortex	1.00	infobox
DNAJA3	Bgee	apex of heart	1.00	infobox
DNAJA3	Bgee	interventricular septum	1.00	infobox
DNAJA3	Bgee	Ileal epithelium	1.00	infobox
DNAJA3	Bgee	extensor digitorum longus muscle	1.00	infobox
DNAJA3	Bgee	brown adipose tissue	1.00	infobox
DNAJA3	Bgee	right kidney	1.00	infobox
DNAJA3	Bgee	plantaris muscle	1.00	infobox
DNAJA3	Bgee	soleus muscle	1.00	infobox
DNAJA3	Bgee	digastric muscle	1.00	infobox
DNAJA3	Bgee	myocardium of ventricle	1.00	infobox
DNAJA3	Bgee	sternocleidomastoid muscle	1.00	infobox
DNAJA3	BioGPS	More reference expression data	1.00	infobox
DNAJA3	Chr.	Chromosome 16 (human)	1.00	infobox
DNAJA3	Chr.	Chromosome 16 (mouse)	1.00	infobox
DNAJA3	Databases	NCBI: entry; OMA: entry	1.00	infobox
DNAJA3	End	4,456,775 bp	1.00	infobox
DNAJA3	End	4,525,559 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DNAJA3 bring nearby vocabulary together. In this analysis, examples include Cell, Mitochondrial and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

DNAJA3
- Cell
- Mitochondrial
- Function
- Member
- Complex
- Family
- Gene
- Hsp40
- Hsp70
- Mitochondria
- Protein
- Apoptosis
dnaja3
- Cell
- Mitochondrial
- Function
- Member
- Complex
- Family
- Gene
- Hsp40
- Hsp70
- Mitochondria
- Protein
- Apoptosis
mitochondrial dna
- Cellular
- Protein
- Membrane
- Cell
- Death
- Growth
- Involved
- Maintaining
- Mtdna
- Hsp70
- Potential
- Mouse
mitochondrial
- Cellular
- Protein
- Membrane
- Cell
- Death
- Growth
- Involved
- Maintaining
- Mtdna
- Hsp70
- Potential
- Mouse
mitochondrial matrix
- Cellular
- Protein
- Membrane
- Cell
- Death
- Growth
- Involved
- Maintaining
- Mtdna
- Hsp70
- Potential
- Mouse
protein folding
- Hsp40
- Hsp70
- Complex
- Assembly
- Member
- Folding
- Protein
- Death
- Known
- Mouse
- Membrane
- Cellular
multiprotein complex
- Assembly
- Folding
- Family
- Hsp40
- Hsp70
- Dnaj
- Member
- Membrane
- Protein
- Dnaja3
- Death
- Known
mitochondrial fission
- Cellular
- Protein
- Membrane
- Cell
- Death
- Growth
- Involved
- Maintaining
- Mtdna
- Hsp70
- Potential
- Mouse

Connections between topic areas Semantic bridges

For DNAJA3, one of the stronger structural bridges in this analysis connects DNAJA3 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

DNAJA3 — Clinical significance · splits 46 ⟂ 21

DNAJA3 — Function · splits 48 ⟂ 19

DNAJA3 — Overview · splits 54 ⟂ 13

DNAJA3 — Structure · splits 60 ⟂ 7

DNAJA3 — Interactions · splits 61 ⟂ 6

Map overview Semantic statistics

DNAJA3

Nodes67

Edges66

Triples165

Avg. degree1.97

Density0.029851

Components1

Source & methodology

TTTA analyzes the structure around DNAJA3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DNAJA3 · EN edition · Analysis: TopicsToTalkAbout