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DNAJA3

DnaJ homolog subfamily A member 3, mitochondrial, also known as Tumorous imaginal disc 1 (TID1), is a protein that in humans is encoded by the DNAJA3 gene on chromosome 16. This protein belongs to the DNAJ/Hsp40 protein family, which is known for binding and activating Hsp70 chaperone proteins to perform protein folding, degradation, and complex…

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Aliases
DNAJA3, HCA57, TID1, hTID-1, DnaJ heat shock protein family (Hsp40) member A3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CTT, 2DN9
Band
16p13.3 · 16 A1|16 2.46 cM
Bgee
gastrocnemius muscle · skeletal muscle tissue · muscle of thigh · right adrenal gland · right adrenal cortex
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 16 (mouse)

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DNAJA3

Nodes67
Edges66
Triples165
Avg. degree1.97
Density0.029851
Components1

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DNAJA3

Top relations

Gene ontology · 54
DNAJA3 → actin filament, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation-induced cell death of T cells, apoptotic process, ATP binding, cell junction, cytoplasm, cytosol, extrinsic component of plasma membrane, GTPase regulator activity, heat shock protein binding, Hsp70 protein binding, I-kappaB/NF-kappaB complex, IkappaB kinase complex, interferon-gamma receptor binding, intracellular membrane-bounded organelle, membrane, metal ion binding, mitochondrial DNA replication, mitochondrial matrix
Bgee · 20
DNAJA3 → apex of heart, brown adipose tissue, digastric muscle, extensor digitorum longus muscle, gastrocnemius muscle, Ileal epithelium, interventricular septum, left adrenal cortex, left adrenal gland, left ventricle, muscle of thigh, myocardium of ventricle, plantaris muscle, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle
RNA expression pattern · 20
DNAJA3 → apex of heart, brown adipose tissue, digastric muscle, extensor digitorum longus muscle, gastrocnemius muscle, Ileal epithelium, interventricular septum, left adrenal cortex, left adrenal gland, left ventricle, muscle of thigh, myocardium of ventricle, plantaris muscle, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle
related to Clinical significance · 16
DNAJA3 → Additionally, AKT, Another, EGFR, ErbB2, HNSCC, HSP27, In, It, MDM2, MK5, Moreover, Parkinson's, This, Thus, Under
related to Structure · 11
DNAJA3 → As, C-terminal, DnaJ, DNAJ/Hsp40, G/F, HPD, Hsp70, In, N-terminal, The, The DnaJ
related to Function · 10
DNAJA3 → ATPase, Before, DNAJ/Hsp40, DRP1, However, Hsp70, In, The, These, This
Band · 2
DNAJA3 → 16 A1|16 2.46 cM, 16p13.3
Chr. · 2
DNAJA3 → Chromosome 16 (human), Chromosome 16 (mouse)
End · 2
DNAJA3 → 4,456,775 bp, 4,525,559 bp
related to Interactions · 2
DNAJA3 → ErbB-2, JAK2

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Important terminology

protein mitochondrial dnaj bp chromosome 16 hsp70 cell chr human band membrane gene complex hsp40 function member family isoform also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DNAJA3AliasesDNAJA3, HCA57, TID1, hTID-1, DnaJ heat shock protein family (Hsp40) member A31.00infobox
DNAJA3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CTT, 2DN91.00infobox
DNAJA3Band16p13.31.00infobox
DNAJA3Band16 A1|16 2.46 cM1.00infobox
DNAJA3Bgeegastrocnemius muscle1.00infobox
DNAJA3Bgeeskeletal muscle tissue1.00infobox
DNAJA3Bgeemuscle of thigh1.00infobox
DNAJA3Bgeeright adrenal gland1.00infobox
DNAJA3Bgeeright adrenal cortex1.00infobox
DNAJA3Bgeeright lobe of liver1.00infobox
DNAJA3Bgeeleft adrenal gland1.00infobox
DNAJA3Bgeeleft ventricle1.00infobox
DNAJA3Bgeeleft adrenal cortex1.00infobox
DNAJA3Bgeeapex of heart1.00infobox
DNAJA3Bgeeinterventricular septum1.00infobox
DNAJA3BgeeIleal epithelium1.00infobox
DNAJA3Bgeeextensor digitorum longus muscle1.00infobox
DNAJA3Bgeebrown adipose tissue1.00infobox
DNAJA3Bgeeright kidney1.00infobox
DNAJA3Bgeeplantaris muscle1.00infobox
DNAJA3Bgeesoleus muscle1.00infobox
DNAJA3Bgeedigastric muscle1.00infobox
DNAJA3Bgeemyocardium of ventricle1.00infobox
DNAJA3Bgeesternocleidomastoid muscle1.00infobox
DNAJA3BioGPSMore reference expression data1.00infobox
DNAJA3Chr.Chromosome 16 (human)1.00infobox
DNAJA3Chr.Chromosome 16 (mouse)1.00infobox
DNAJA3DatabasesNCBI: entry; OMA: entry1.00infobox
DNAJA3End4,456,775 bp1.00infobox
DNAJA3End4,525,559 bp1.00infobox

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