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Cyproterone acetate

Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing horm…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Micromedex Detailed Consumer Information
ATC code
G03HA01 (WHO)
Bioavailability
Oral: 68–100%
CAS Number
427-51-0 Y 2098-66-0 (free alcohol)
ChEBI
CHEBI:50743 Y

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Pharmacology

Chemistry

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Cyproterone acetate

Nodes293
Edges292
Triples136
Avg. degree1.99
Density0.006826
Components1

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Cyproterone acetate

Top relations

related to Generic names · 22
Cyproterone acetate → BANTooltip British Approved Name, CPA, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, Dutch, French, German, INNTooltip International Nonproprietary Name, Italian, JANTooltip Japanese Accepted Name, Latin, Name, SH-714, SH-80714, SH-80881, SH-881, Spanish, The, The English, These
related to External links · 16
Cyproterone acetate → Arznei-Telegramm, Contraceptive, Die Geschichte, Empfängnisschutz, From, German, Google Translate, Hautpflegemittel, Mann, Men, Pill, Pille, Skin Care Product, The History, Von, Wirkstoffs Cyproteronazetat
related to Synthesis · 12
Cyproterone acetate → C1, C2, C6, C7, Chemical, CID, CPA, Dehydrogenation, Reacting, Selective, The, This
related to Pharmacokinetics · 3
Cyproterone acetate → CPA, It, OH-CPA
3D model (JSmol) · 1
Cyproterone acetate → Interactive image
AHFS/Drugs.com · 1
Cyproterone acetate → Micromedex Detailed Consumer Information
ATC code · 1
Cyproterone acetate → G03HA01 (WHO)
Bioavailability · 1
Cyproterone acetate → Oral: 68–100%
CAS Number · 1
Cyproterone acetate → 427-51-0 Y 2098-66-0 (free alcohol)
ChEBI · 1
Cyproterone acetate → CHEBI:50743 Y

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Important terminology

cpa used treatment antiandrogen combination effects prostate cancer birth control women mg androgen men also high cyproterone day use ethinylestradiol

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cyproterone acetate3D model (JSmol)Interactive image1.00infobox
Cyproterone acetateAHFS/Drugs.comMicromedex Detailed Consumer Information1.00infobox
Cyproterone acetateATC codeG03HA01 (WHO)1.00infobox
Cyproterone acetateBioavailabilityOral: 68–100%1.00infobox
Cyproterone acetateCAS Number427-51-0 Y 2098-66-0 (free alcohol)1.00infobox
Cyproterone acetateChEBICHEBI:50743 Y1.00infobox
Cyproterone acetateChEMBLChEMBL139835 Y1.00infobox
Cyproterone acetateChemSpider9496 Y1.00infobox
Cyproterone acetateCompTox Dashboard (EPA)DTXSID50203661.00infobox
Cyproterone acetateDrug classSteroidal antiandrogen; Progestin; Progestogen ester; Antigonadotropin1.00infobox
Cyproterone acetateDrugBankDB048391.00infobox
Cyproterone acetateECHA InfoCard100.006.4091.00infobox
Cyproterone acetateElimination half-lifeOral: 1.6–4.3 days IM: 3–4.3 days1.00infobox
Cyproterone acetateExcretionFeces: 70% Urine: 30%1.00infobox
Cyproterone acetateFormulaC24H29ClO41.00infobox
Cyproterone acetateIUPHAR/BPS28651.00infobox
Cyproterone acetateKEGGD013681.00infobox
Cyproterone acetateLegal statusIn general: ℞ (Prescription only)1.00infobox
Cyproterone acetateMelting point200 to 201 °C (392 to 394 °F)1.00infobox
Cyproterone acetateMetabolismHepatic (CYP3A4)1.00infobox
Cyproterone acetateMetabolites• 15β-OH-CPATooltip 15β-Hydroxycyproterone acetate (major) • Cyproterone (minor) • Acetic acid (minor)1.00infobox
Cyproterone acetateMolar mass416.94 g·mol−11.00infobox
Cyproterone acetateOther namesSH-80714; SH-714; NSC-81430; 1α,2α-Methylene-6-chloro-17α-hydroxy-δ6-progesterone acetate; 1α,2α-Methylene-6-chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate1.00infobox
Cyproterone acetatePregnancy categoryX1.00infobox
Cyproterone acetateProtein bindingAlbumin: 93% Free: 7%1.00infobox
Cyproterone acetatePubChem CID98801.00infobox
Cyproterone acetateRoutes of administrationBy mouth, intramuscular1.00infobox
Cyproterone acetateTrade namesAndrocur, Androcur Depot, Cyprostat, Siterone, Procur, others1.00infobox
Cyproterone acetateUNII4KM2BN5JHF1.00infobox

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