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Leuprorelin

Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, for early puberty, as part of transgender hormone therapy, or to perform chemical castration of violent sex offenders. It is given by injection into a muscle or under the skin.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L02AE02 (WHO)
CAS Number
53714-56-0 Y 74381-53-6 (acetate)
ChEMBL
ChEMBL1201199 N
ChemSpider
571356 N

Topics to explore

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Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Society and culture

Research

Veterinary use

Advanced semantic analysis

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Map overview Semantic statistics

Leuprorelin

Nodes103
Edges102
Triples135
Avg. degree1.98
Density0.019417
Components1

How this topic connects Entity context

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Leuprorelin

Top relations

related to history · 26
Leuprorelin → Abbott Laboratories, Between, Douglas Durand, Durand, False Claims Act, FDA, Gerstein, In October, It, Joseph Gerstein, Justice, Lupron, Medicaid, Medicare, Prescription Drug Marketing Act, Since, TAP, TAP Pharmaceutical Products, The, The FDA
related to Names · 26
Leuprorelin → A-43818, Abbott Laboratories, Abbott-43818, BANMTooltip British Approved Name, BANTooltip British Approved Name, Bayer AG, DC-2-269, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, Eligard, Fensolvi, INNTooltip International Nonproprietary Name, It, JANTooltip Japanese Accepted Name, Leupromer, Lupron, Name, Previously, TAP Pharmaceuticals, TAP-144
related to Legal status · 13
Leuprorelin → Accord Healthcare, Camcevi, CHMP, Committee, EMA, European Medicines Agency, European Union, Human Use, March, May, Medicinal Products, On, The
related to Available forms · 10
Leuprorelin → Camcevi, Eligard, Fensolvi, Leuprolide, Long-acting, Lupaneta Pack, Lupron, Lupron Depot, Short-acting, Viadur
related to Mechanism of action · 7
Leuprorelin → Continuous, FSH, GnRH, However, HPG, LH, This
related to Research · 7
Leuprorelin → Alzheimer's, As, II, It, July, Ovarest, The
Legal status · 5
Leuprorelin → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
has effect · 4
Leuprorelin → Common, FDA, However, The
related to Medical uses · 4
Leuprorelin → It, IVF, Lupron, This
related to Veterinary use · 2
Leuprorelin → It, Its

Important terminology Word statistics

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Important terminology

treatment testosterone use used lupron hormone puberty prostate cancer approved may fda injection effects also side drug gnrh leuprolide agonist

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Leuprorelin3D model (JSmol)Interactive image1.00infobox
LeuprorelinAHFS/Drugs.comMonograph1.00infobox
LeuprorelinATC codeL02AE02 (WHO)1.00infobox
LeuprorelinCAS Number53714-56-0 Y 74381-53-6 (acetate)1.00infobox
LeuprorelinChEMBLChEMBL1201199 N1.00infobox
LeuprorelinChemSpider571356 N1.00infobox
LeuprorelinCompTox Dashboard (EPA)DTXSID508724111.00infobox
LeuprorelinDrug classGnRH analogue; GnRH agonist; Antigonadotropin1.00infobox
LeuprorelinDrugBankDB00007 Y1.00infobox
LeuprorelinECHA InfoCard100.161.4661.00infobox
LeuprorelinElimination half-life3 hours1.00infobox
LeuprorelinExcretionKidney1.00infobox
LeuprorelinFormulaC59H84N16O121.00infobox
LeuprorelinIUPHAR/BPS11751.00infobox
LeuprorelinKEGGD08113 Y1.00infobox
LeuprorelinLegal statusAU: S4 (Prescription only)1.00infobox
LeuprorelinLegal statusCA: ℞-only1.00infobox
LeuprorelinLegal statusUS: ℞-only1.00infobox
LeuprorelinLegal statusEU: Rx-only1.00infobox
LeuprorelinLegal statusIn general: ℞ (Prescription only)1.00infobox
LeuprorelinLicense dataUS DailyMed: Leuprolide1.00infobox
LeuprorelinMedlinePlusa6850401.00infobox
LeuprorelinMolar mass1209.421 g·mol−11.00infobox
LeuprorelinOther namesleuprolide, leuprolidine, A-43818, Abbott-43818, DC-2-269, TAP-1441.00infobox
LeuprorelinPregnancy categoryAU: D1.00infobox
LeuprorelinPubChem CID6571811.00infobox
LeuprorelinRoutes of administrationimplant, subcutaneous, intramuscular1.00infobox
LeuprorelinTrade namesLupron, Eligard, Lucrin, Lupaneta, others1.00infobox
LeuprorelinUNIIEFY6W0M8TG1.00infobox

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